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• W2065362153 abstract "Abstract Alpha-lipoic acid (LA) as a dietary supplement strongly scavenges free radicals. The negative relationship between oxidative stress and bone formation has recently been reported. Here, we investigated the protective effects of LA on the hydrogen peroxide-induced oxidative stress and impaired calcification in MC3T3-E1 osteoblast-like cells. After exposure to H 2 O 2 , there was a decrease in the levels of calcification and reduced glutathione but an increase in thiobarbituric acid-reactive substances levels in the no LA-treated cells. The presence of LA attenuated oxidative stress and significantly enhanced calcification capacity at 0.1 and 1.0 mM ( P  2 O 2 -induced oxidative damage to mineralization." @default.
• W2065362153 created "2016-06-24" @default.
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• W2065362153 date "2012-07-01" @default.
• W2065362153 modified "2023-09-25" @default.
• W2065362153 title "Alpha-lipoic acid protects against hydrogen peroxide-induced oxidative stress in MC3T3-E1 osteoblast-like cells" @default.
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• W2065362153 doi "https://doi.org/10.1016/j.jff.2012.04.004" @default.
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