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- W2065404469 abstract "Protein regions (genomic DNA) and cDNA sequences can be rapidly to help identify them. If a three-dimensional fold can also be identified, then modelling can provide an estimate of the protein's structure, which can both in drug design and in probing structure—function relationships. Methods linking one-dimensional information, represented by the sequence, to three-dimensional information of the protein fold are key to this progression of events. The major difficulty lies with the identification of related proteins whose sequences have diverged beyond recognition, while their folds remain similar enough to confirm their descent from a common ancestor." @default.
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- W2065404469 date "1995-07-01" @default.
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- W2065404469 title "Cornering and catching the common protein fold" @default.
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- W2065404469 doi "https://doi.org/10.1016/s1357-4310(95)91909-0" @default.
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