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- W2065425391 abstract "To better understand the long-term weight stability of postobese patients who underwent biliopancreatic diversion (BPD), we studied 24-h energy and nutrient balance in eight women at least 3 yr after surgery (PO) and compared the results to those obtained in eight normal never-obese control women (C), matched by age and weight. Body composition was measured by dual-energy x-ray absorptiometry (DXA). All the patients were on an ad libitum diet; 24-h energy and nutrient intake were measured on the experimental day. Twenty-four-hour energy expenditure (EE) and 24-h nutrient oxidation rates were measured in a respiratory chamber, and energy and nutrient balances were calculated after correcting for 24-h fecal nutrient loss. No differences in body composition were found between PO and C. PO had a higher gross energy intake than C (10.6 ± 3.4 vs. 8.0 ± 2.2 MJ/d; p < 0.05); however, due to the higher energy fecal loss in PO as compared to C (2.4 ± 1.3 vs. 0.09 ± 0.01 MJ/day; p < 0.01), 24-h metabolizable energy intake (MEI) was not different in the two groups. The energy fecal loss in the PO patients was mostly in the form of lipid. EE at 24 h was not different in PO as compared to C. Therefore energy balance, computed as the difference between 24-h MEI and 24-h EE, was similar in the two groups. Respiratory quotient was significantly higher in PO than in C (1.00 ± 0.08 vs. 0.83 ± 0.03; p < 0.01). Carbohydrate (−135 ± 37 g/d in PO vs. 63 ± 23 g/d in C; p < 0.001), and lipid (48 ± 14 g/d in PO vs. −23 ± 6 g/d in C; p < 0.001) balances were different in the two groups. We conclude that chronic lipid malabsorption was the main metabolic abnormality explaining the achievement of energy balance in postobese subjects after biliopancreatic diversion. A chronic reduction of lipid absorption seems to play a key role in the long-term weight stability of this group of postobese subjects." @default.
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- W2065425391 date "1996-04-01" @default.
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- W2065425391 title "Twenty-four-hour energy and nutrient balance in weight stable postobese patients after biliopancreatic diversion" @default.
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- W2065425391 doi "https://doi.org/10.1016/s0899-9007(96)90849-7" @default.
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