FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2065432922> ?p ?o ?g. }

• W2065432922 endingPage "242" @default.
• W2065432922 startingPage "237" @default.
• W2065432922 abstract "This study evaluated the effects of high-frequency oscillation (HFO) and conventional mechanical ventilation (CMV) on gas exchange and the pulmonary surfactant system in an acute lung injury model. Following induction of lung injury with N-nitroso-n-methylurethane, adult rabbits were anesthetized and randomized to one of the following ventilatory strategies: HFO for 120 min, CMV for 120 min, HFO for 60 min, followed by CMV for 60 min, CMV for 60 min followed by HFO for 60 min or CMV for 60 min. Separate animals were ventilated using CMV with a lower tidal volume and a positive end-expiratory pressure level that was increased throughout the experimental period. Oxygenation was significantly greater in animals ventilated with HFO compared with animals ventilated with CMV. The proportion of surfactant in large aggregate forms was significantly greater following ventilatory support with HFO compared with CMV. Surfactant aggregate conversion was also significantly lower during HFO compared with CMV. We conclude that in our model of acute lung injury, HFO was a superior mode of ventilation and reduced the conversion of alveolar surfactant large aggregates into small aggregate forms, resulting in a greater percentage of large aggregate forms in the alveolar space.Keywords: surfactant; mechanical ventilation; ARDS" @default.
• W2065432922 created "2016-06-24" @default.
• W2065432922 creator A5052883165 @default.
• W2065432922 creator A5065004521 @default.
• W2065432922 creator A5076681208 @default.
• W2065432922 date "2001-07-15" @default.
• W2065432922 modified "2023-10-18" @default.
• W2065432922 title "Effects of High-Frequency Oscillation on Endogenous Surfactant in an Acute Lung Injury Model" @default.
• W2065432922 cites W1775749144 @default.
• W2065432922 cites W1858048946 @default.
• W2065432922 cites W1910726787 @default.
• W2065432922 cites W1964459092 @default.
• W2065432922 cites W1969316633 @default.
• W2065432922 cites W1983843998 @default.
• W2065432922 cites W1987231766 @default.
• W2065432922 cites W1988708038 @default.
• W2065432922 cites W1996615948 @default.
• W2065432922 cites W2009478257 @default.
• W2065432922 cites W2010753913 @default.
• W2065432922 cites W2020821849 @default.
• W2065432922 cites W2050896066 @default.
• W2065432922 cites W2056802466 @default.
• W2065432922 cites W2067879188 @default.
• W2065432922 cites W2075621846 @default.
• W2065432922 cites W2087037775 @default.
• W2065432922 cites W2097359199 @default.
• W2065432922 cites W2127708759 @default.
• W2065432922 cites W2144964209 @default.
• W2065432922 cites W2152311269 @default.
• W2065432922 cites W2161328469 @default.
• W2065432922 cites W2166443939 @default.
• W2065432922 cites W2209748026 @default.
• W2065432922 cites W2219405260 @default.
• W2065432922 cites W3173074521 @default.
• W2065432922 cites W4285149548 @default.
• W2065432922 doi "https://doi.org/10.1164/ajrccm.164.2.2007144" @default.
• W2065432922 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11463594" @default.
• W2065432922 hasPublicationYear "2001" @default.
• W2065432922 type Work @default.
• W2065432922 sameAs 2065432922 @default.
• W2065432922 citedByCount "27" @default.
• W2065432922 countsByYear W20654329222012 @default.
• W2065432922 countsByYear W20654329222014 @default.
• W2065432922 countsByYear W20654329222017 @default.
• W2065432922 countsByYear W20654329222021 @default.
• W2065432922 crossrefType "journal-article" @default.
• W2065432922 hasAuthorship W2065432922A5052883165 @default.
• W2065432922 hasAuthorship W2065432922A5065004521 @default.
• W2065432922 hasAuthorship W2065432922A5076681208 @default.
• W2065432922 hasConcept C126322002 @default.
• W2065432922 hasConcept C127413603 @default.
• W2065432922 hasConcept C177713679 @default.
• W2065432922 hasConcept C185592680 @default.
• W2065432922 hasConcept C200457457 @default.
• W2065432922 hasConcept C27101514 @default.
• W2065432922 hasConcept C2776178081 @default.
• W2065432922 hasConcept C2776348555 @default.
• W2065432922 hasConcept C2776691311 @default.
• W2065432922 hasConcept C2777080012 @default.
• W2065432922 hasConcept C2777257755 @default.
• W2065432922 hasConcept C2777387402 @default.
• W2065432922 hasConcept C2777714996 @default.
• W2065432922 hasConcept C2778917391 @default.
• W2065432922 hasConcept C2987404301 @default.
• W2065432922 hasConcept C42219234 @default.
• W2065432922 hasConcept C534529494 @default.
• W2065432922 hasConcept C55493867 @default.
• W2065432922 hasConcept C58226133 @default.
• W2065432922 hasConcept C70289976 @default.
• W2065432922 hasConcept C71924100 @default.
• W2065432922 hasConcept C78519656 @default.
• W2065432922 hasConceptScore W2065432922C126322002 @default.
• W2065432922 hasConceptScore W2065432922C127413603 @default.
• W2065432922 hasConceptScore W2065432922C177713679 @default.
• W2065432922 hasConceptScore W2065432922C185592680 @default.
• W2065432922 hasConceptScore W2065432922C200457457 @default.
• W2065432922 hasConceptScore W2065432922C27101514 @default.
• W2065432922 hasConceptScore W2065432922C2776178081 @default.
• W2065432922 hasConceptScore W2065432922C2776348555 @default.
• W2065432922 hasConceptScore W2065432922C2776691311 @default.
• W2065432922 hasConceptScore W2065432922C2777080012 @default.
• W2065432922 hasConceptScore W2065432922C2777257755 @default.
• W2065432922 hasConceptScore W2065432922C2777387402 @default.
• W2065432922 hasConceptScore W2065432922C2777714996 @default.
• W2065432922 hasConceptScore W2065432922C2778917391 @default.
• W2065432922 hasConceptScore W2065432922C2987404301 @default.
• W2065432922 hasConceptScore W2065432922C42219234 @default.
• W2065432922 hasConceptScore W2065432922C534529494 @default.
• W2065432922 hasConceptScore W2065432922C55493867 @default.
• W2065432922 hasConceptScore W2065432922C58226133 @default.
• W2065432922 hasConceptScore W2065432922C70289976 @default.
• W2065432922 hasConceptScore W2065432922C71924100 @default.
• W2065432922 hasConceptScore W2065432922C78519656 @default.
• W2065432922 hasIssue "2" @default.
• W2065432922 hasLocation W20654329221 @default.
• W2065432922 hasLocation W20654329222 @default.
• W2065432922 hasOpenAccess W2065432922 @default.
• W2065432922 hasPrimaryLocation W20654329221 @default.

• next