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- W2065436482 endingPage "47" @default.
- W2065436482 startingPage "23" @default.
- W2065436482 abstract "A theoretical model for predicting intrinsic and induced DNA superstructures as well as their thermodynamic properties is presented. Intrinsic sequence-dependent superstructures are evaluated by integrating local deviations from the canonical B-DNA of the different dinucleotide steps. Induced superstructures are obtained by adopting the principle of minimum deformation free energy, evaluated in the Fourier space, in the framework of first-order elasticity. Finally dinucleotide stacking energies and melting temperatures are considered to account for local flexibility. In fact the two scales are strongly correlated. The model works very satisfactorily in predicting the sequence-dependent effects on the DNA experimental behavior, such as the gel electrophoresis retardation, the writhe transitions in topologically constrained domains, the thermodynamic constants of circularization reactions as well as the nucleosome thermodynamic stability constants." @default.
- W2065436482 created "2016-06-24" @default.
- W2065436482 creator A5012414509 @default.
- W2065436482 creator A5020121238 @default.
- W2065436482 creator A5025999301 @default.
- W2065436482 creator A5053933197 @default.
- W2065436482 creator A5088853430 @default.
- W2065436482 date "2002-01-01" @default.
- W2065436482 modified "2023-10-08" @default.
- W2065436482 title "From the sequence to the superstructural properties of DNAs" @default.
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