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- W2065458030 abstract "Estrone-6,7-3H was administered to a group of male dogs, which were then sacrificed at 10, 30 and 120 min. Samples of plasma, liver, kidney, heart, omentum and (in a separate experiment) urine were obtained and analyzed for specific radioactive estrogens. Identification was carried out by column partition chromatography and by co-crystallization with authentic nonradioactive estrogen standards. Estrone and estradiol-17β were found in all tissues, plasma and urine. Preferential concentration of estrone was observed in omentum. There was no preferential concentration of estradiol-17β in any tissue. No 2-methoxyestrone was found in any tissue, plasma or urine. There was some evidence for estradiol-17α in liver, but identification was incomplete. Estriol-16α, 17α was found in all urines in relatively high yield. Only traces of estriol were found in 2 of 4 urines. Small amounts of estriol-16α,17α were found in liver and kidney, but not in other tissues or plasma. No other estriol epimers were found in any tiss..." @default.
- W2065458030 created "2016-06-24" @default.
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- W2065458030 date "1968-03-01" @default.
- W2065458030 modified "2023-09-24" @default.
- W2065458030 title "Estrogen Metabolism in the Male Dog. Uptake and Disappearance of Specific Radioactive Estrogens in Tissues and Plasma Following Estrone-6,7-3H Administration. Identification of Estriol-16α, 17αin Tissues and Urine1" @default.
- W2065458030 doi "https://doi.org/10.1210/endo-82-3-500" @default.
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