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- W2065506462 abstract "Abstract #4028 Background: High quality of space and temporal resolution is demanded from the diagnosis for intraductal spreading area of breast cancer. In our hospital, from April 2007, 3-Tesra (T) MRI was transduced and high resolution dynamic studies for bilateral mammary have been performed. However, superiority of 3-T MRI to 1.5-T MRI remains almost unproven in the evaluation of intraductal spreading area of breast cancer. Methods: We assessed 46 patients with primary ductal carcinoma in situ who underwent the 3-T or 1.5-T breast MRI as pre-operative examination between July, 2007 and March, 2008. Concerning the diagnosis of intraductal spreading area of breast cancer, we weighed 3T MRI against conventional 1.5T MRI. Using 1.5-T or 3-T MRI (Achieva, Philips), we injected contrast medium (Magnepist) with 0.2ml/kg body weight in 1ml/sec and photographed five aspects before injection and after injection for every 90 seconds. We obtained fat-sat T1-weighted magnetic resonance image (T1WI), multi-planar reconstruction (MPR) image and standard maximum intensity projection (MIP) image based on T1WI by coronal section, and furthermore slab MIP image with Aquerius net (Terarecon), and we evaluated the enhanced area. Results: 32 cases were examed with 1.5-T MRI, and 14 cases with 3-T MRI. In 1.5-T group, 10 cases (31%) were underestimated, additional resection were required intraoperativelly with cancer-cells positive surgical margin in 7 cases, and surgical margin was positive with carcinoma cells by final pathological findings in 4 cases. In one patient we were forced to changes from breast-conserving surgery to mastectomy, and two cases underwent reoperation (mastectomy) with the diagnosis of widely positive surgical margin.In comparison with 1.5 T MRI group, three (21%) were underestimated in 3-T MRI group, intraoperative addition resection in two cases, and surgical margin positive by the final pathological findings in two cases, respectively. Conclusions: The concern to enhance an artifact is known because 3-T MRI has high resolution, but it may be more useful in the evaluation of intraductal spreading area of breast cancer. Citation Information: Cancer Res 2009;69(2 Suppl):Abstract nr 4028." @default.
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- W2065506462 date "2009-01-15" @default.
- W2065506462 modified "2023-09-27" @default.
- W2065506462 title "3-Tesla MRI for the evaluation of spreading area of ductal carcinoma in situ: a comparative study with 1.5-Tesla MRI." @default.
- W2065506462 doi "https://doi.org/10.1158/0008-5472.sabcs-4028" @default.
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