FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2065507917> ?p ?o ?g. }

• W2065507917 endingPage "27" @default.
• W2065507917 startingPage "17" @default.
• W2065507917 abstract "Multi Drug Resistance (MDR) in Acinetobacter baumannii is one of the major threats for emerging nosocomial infections in hospital environment. Multidrug-resistance in A. baumannii may be due to the implementation of multi-combination resistance mechanisms such as β-lactamase synthesis, Penicillin-Binding Proteins (PBPs) changes, alteration in porin proteins and in efflux pumps against various existing classes of antibiotics. Multiple antibiotic resistance genes are involved in MDR. These resistance genes are transferred through plasmids, which are responsible for the dissemination of antibiotic resistance among Acinetobacter spp. In addition, these resistance genes may also have a tendency to interact with each other or with their gene products. Therefore, it becomes necessary to understand the impact of these interactions in antibiotic resistance mechanism. Hence, our study focuses on protein and gene network analysis on various resistance genes, to elucidate the role of the interacting proteins and to study their functional contribution towards antibiotic resistance. From the search tool for the retrieval of interacting gene/protein (STRING), a total of 168 functional partners for 15 resistance genes were extracted based on the confidence scoring system. The network study was then followed up with functional clustering of associated partners using molecular complex detection (MCODE). Later, we selected eight efficient clusters based on score. Interestingly, the associated protein we identified from the network possessed greater functional similarity with known resistance genes. This network-based approach on resistance genes of A. baumannii could help in identifying new genes/proteins and provide clues on their association in antibiotic resistance." @default.
• W2065507917 created "2016-06-24" @default.
• W2065507917 creator A5010336878 @default.
• W2065507917 creator A5044438568 @default.
• W2065507917 creator A5087677407 @default.
• W2065507917 date "2014-05-01" @default.
• W2065507917 modified "2023-09-24" @default.
• W2065507917 title "Computational gene network study on antibiotic resistance genes of Acinetobacter baumannii" @default.
• W2065507917 cites W1479996560 @default.
• W2065507917 cites W1622147335 @default.
• W2065507917 cites W1836076697 @default.
• W2065507917 cites W1994183353 @default.
• W2065507917 cites W1998157707 @default.
• W2065507917 cites W2003473175 @default.
• W2065507917 cites W2008274231 @default.
• W2065507917 cites W2014408727 @default.
• W2065507917 cites W2022772561 @default.
• W2065507917 cites W2025605962 @default.
• W2065507917 cites W2026773629 @default.
• W2065507917 cites W2029078413 @default.
• W2065507917 cites W2030323881 @default.
• W2065507917 cites W2057545775 @default.
• W2065507917 cites W2059849208 @default.
• W2065507917 cites W2064740494 @default.
• W2065507917 cites W2066169311 @default.
• W2065507917 cites W2069248883 @default.
• W2065507917 cites W2073556554 @default.
• W2065507917 cites W2074948884 @default.
• W2065507917 cites W2096026358 @default.
• W2065507917 cites W2096898012 @default.
• W2065507917 cites W2097795961 @default.
• W2065507917 cites W2105838577 @default.
• W2065507917 cites W2105924489 @default.
• W2065507917 cites W2110991941 @default.
• W2065507917 cites W2112586763 @default.
• W2065507917 cites W2113613985 @default.
• W2065507917 cites W2116542556 @default.
• W2065507917 cites W2119666325 @default.
• W2065507917 cites W2122683221 @default.
• W2065507917 cites W2124804822 @default.
• W2065507917 cites W2131374386 @default.
• W2065507917 cites W2131673842 @default.
• W2065507917 cites W2134352676 @default.
• W2065507917 cites W2135113667 @default.
• W2065507917 cites W2135805255 @default.
• W2065507917 cites W2136850043 @default.
• W2065507917 cites W2144038123 @default.
• W2065507917 cites W2145506897 @default.
• W2065507917 cites W2149593850 @default.
• W2065507917 cites W2150953085 @default.
• W2065507917 cites W2153969539 @default.
• W2065507917 cites W2154139219 @default.
• W2065507917 cites W2158217645 @default.
• W2065507917 cites W2159135076 @default.
• W2065507917 cites W2159435953 @default.
• W2065507917 cites W2159675211 @default.
• W2065507917 cites W2161447988 @default.
• W2065507917 cites W2163480486 @default.
• W2065507917 cites W2165623974 @default.
• W2065507917 cites W2167969340 @default.
• W2065507917 cites W2171535756 @default.
• W2065507917 cites W2172046337 @default.
• W2065507917 cites W2176123637 @default.
• W2065507917 cites W2327398006 @default.
• W2065507917 cites W2334070615 @default.
• W2065507917 cites W2885753884 @default.
• W2065507917 doi "https://doi.org/10.1016/j.compbiomed.2014.02.009" @default.
• W2065507917 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24637144" @default.
• W2065507917 hasPublicationYear "2014" @default.
• W2065507917 type Work @default.
• W2065507917 sameAs 2065507917 @default.
• W2065507917 citedByCount "26" @default.
• W2065507917 countsByYear W20655079172014 @default.
• W2065507917 countsByYear W20655079172015 @default.
• W2065507917 countsByYear W20655079172016 @default.
• W2065507917 countsByYear W20655079172017 @default.
• W2065507917 countsByYear W20655079172018 @default.
• W2065507917 countsByYear W20655079172019 @default.
• W2065507917 countsByYear W20655079172020 @default.
• W2065507917 countsByYear W20655079172021 @default.
• W2065507917 countsByYear W20655079172022 @default.
• W2065507917 countsByYear W20655079172023 @default.
• W2065507917 crossrefType "journal-article" @default.
• W2065507917 hasAuthorship W2065507917A5010336878 @default.
• W2065507917 hasAuthorship W2065507917A5044438568 @default.
• W2065507917 hasAuthorship W2065507917A5087677407 @default.
• W2065507917 hasConcept C104317684 @default.
• W2065507917 hasConcept C114851261 @default.
• W2065507917 hasConcept C133936738 @default.
• W2065507917 hasConcept C200082930 @default.
• W2065507917 hasConcept C22744801 @default.
• W2065507917 hasConcept C2776315533 @default.
• W2065507917 hasConcept C2777637488 @default.
• W2065507917 hasConcept C501593827 @default.
• W2065507917 hasConcept C523546767 @default.
• W2065507917 hasConcept C54355233 @default.
• W2065507917 hasConcept C70721500 @default.
• W2065507917 hasConcept C86803240 @default.

• next