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- W2065544411 abstract "Human platelets contain a Ca2+-ATPase in internal membranes that is essential for Ca2+ homeostasis. This Ca2+ pump has enzymatic properties quite similar to the sarcoplasmic reticulum (SR) Ca2+ pumps. Antibodies against the SR Ca2+ pump crossreact with the human platelet protein. However, the platelet Ca2+-ATPase is approximately 10 kD larger than the SR pumps and exhibits a larger mRNA coding for the protein in a megakaryocyte tumor cell line. In addition, the platelet Ca2+-pump may be localized in specialized internal membrane structures that function in Ca2+ uptake and release. These results suggest that the platelet Ca2+-ATPase may represent a new class of internal membrane Ca2+-pumps." @default.
- W2065544411 created "2016-06-24" @default.
- W2065544411 creator A5046186471 @default.
- W2065544411 date "1989-07-01" @default.
- W2065544411 modified "2023-09-27" @default.
- W2065544411 title "Structure, function and subcellular localization of a human platelet Ca2+-ATPase" @default.
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- W2065544411 doi "https://doi.org/10.1016/0143-4160(89)90055-9" @default.
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