FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2065571723> ?p ?o ?g. }

• W2065571723 endingPage "252" @default.
• W2065571723 startingPage "244" @default.
• W2065571723 abstract "The extracts obtained from Anacardium occidentale leaf were investigated for antioxidant and antimicrobial activities. Bioassay-guided fractionation using DPPH autobiographic analysis of the EtOAc soluble fraction of the crude extract resulted in the isolation of agathisflavone (1) and a mixture of quercetin 3-O-rutinoside (2) and quercetin 3-O-rhamnoside (3). Characterization of the isolated compounds was carried out using nuclear magnetic resonance (1D and 2D) and mass spectrometry. The antioxidant activities of the samples were determined using three complementary tests, namely; DPPH-radical scavenging, total antioxidant capacity (TAC) and ferric reducing antioxidant power (FRAP). The antimicrobial activity of the samples was evaluated using the disc diffusion and broth microdilution methods. The results indicated that the mixture (ratio 2:1) of compounds (2) and (3) was most active in its capacity to scavenge free radicals in the DPPH assay [IC50 = 0.96 ± 0.01 μg/mL] compared to the ethyl acetate (EtOAc) fraction, the ascorbic acid and quercetin standards. The mixture of compounds (2) and (3) exhibited the highest activities in the TAC assay (5332.00 ± 3.38 mg AAE/g, 8562.00 ± 5.43 mg QE/g) and FRAP assay (15,136.00 ± 7.14 mg AAE/g, 199,530.00 ± 94.12 mg QE/g) compared to the EtOAc fraction. The fractions of the extract showed comparatively better activities against gram-negative than the gram positive ones with the broadest spectrum of activities demonstrated for the ethyl acetate fraction. No inhibitions were obtained against the fungal strains investigated. The isolated compounds from the plant possess essentially inhibitory rather than cidal activities against these organisms with the Minimum Bactericidal Concentrations (MBCs) >2.0 mg/mL in all cases. The mixture of compounds 2 and 3 showed higher activity than compound 1 with the former having MIC as low as 0.25 mg/mL against Pseudomonas aeruginosa and Clostridium sporogens, 0.5 mg/mL against Staphylococcus aureus and 1.0 mg/mL against Escherichia coli and Klebsiella pneumonia strains investigated while the latter has an MIC of 1.0 mg/mL against most of the organisms. This study concluded that the extracts and isolated compounds had strong antioxidant and moderate antibacterial activities and could be effective in the management of oxidative stress related diseases. These findings also justified the use of this plant’s extracts in folk medicine." @default.
• W2065571723 created "2016-06-24" @default.
• W2065571723 creator A5001125160 @default.
• W2065571723 creator A5011617425 @default.
• W2065571723 creator A5022570163 @default.
• W2065571723 creator A5044802559 @default.
• W2065571723 date "2015-07-01" @default.
• W2065571723 modified "2023-09-30" @default.
• W2065571723 title "Isolation and characterization of antioxidant and antimicrobial compounds from Anacardium occidentale L. (Anacardiaceae) leaf extract" @default.
• W2065571723 cites W1532672888 @default.
• W2065571723 cites W1624353217 @default.
• W2065571723 cites W1948542047 @default.
• W2065571723 cites W1981491420 @default.
• W2065571723 cites W1994309816 @default.
• W2065571723 cites W1997958925 @default.
• W2065571723 cites W2006915546 @default.
• W2065571723 cites W2010937557 @default.
• W2065571723 cites W2022241552 @default.
• W2065571723 cites W2025150565 @default.
• W2065571723 cites W2029549620 @default.
• W2065571723 cites W2034919962 @default.
• W2065571723 cites W2041016831 @default.
• W2065571723 cites W2041143757 @default.
• W2065571723 cites W2055146165 @default.
• W2065571723 cites W2055952520 @default.
• W2065571723 cites W2060405277 @default.
• W2065571723 cites W2066460879 @default.
• W2065571723 cites W2070482727 @default.
• W2065571723 cites W2071879971 @default.
• W2065571723 cites W2072722433 @default.
• W2065571723 cites W2077013120 @default.
• W2065571723 cites W2080012217 @default.
• W2065571723 cites W2088892363 @default.
• W2065571723 cites W2094815717 @default.
• W2065571723 cites W2104478003 @default.
• W2065571723 cites W2162002392 @default.
• W2065571723 cites W2165615238 @default.
• W2065571723 cites W2327656514 @default.
• W2065571723 cites W2951807403 @default.
• W2065571723 doi "https://doi.org/10.1016/j.jksus.2014.12.004" @default.
• W2065571723 hasPublicationYear "2015" @default.
• W2065571723 type Work @default.
• W2065571723 sameAs 2065571723 @default.
• W2065571723 citedByCount "54" @default.
• W2065571723 countsByYear W20655717232015 @default.
• W2065571723 countsByYear W20655717232016 @default.
• W2065571723 countsByYear W20655717232017 @default.
• W2065571723 countsByYear W20655717232018 @default.
• W2065571723 countsByYear W20655717232019 @default.
• W2065571723 countsByYear W20655717232020 @default.
• W2065571723 countsByYear W20655717232021 @default.
• W2065571723 countsByYear W20655717232022 @default.
• W2065571723 countsByYear W20655717232023 @default.
• W2065571723 crossrefType "journal-article" @default.
• W2065571723 hasAuthorship W2065571723A5001125160 @default.
• W2065571723 hasAuthorship W2065571723A5011617425 @default.
• W2065571723 hasAuthorship W2065571723A5022570163 @default.
• W2065571723 hasAuthorship W2065571723A5044802559 @default.
• W2065571723 hasBestOaLocation W20655717231 @default.
• W2065571723 hasConcept C144027150 @default.
• W2065571723 hasConcept C176947019 @default.
• W2065571723 hasConcept C178790620 @default.
• W2065571723 hasConcept C185592680 @default.
• W2065571723 hasConcept C2778004101 @default.
• W2065571723 hasConcept C2778284287 @default.
• W2065571723 hasConcept C2779054382 @default.
• W2065571723 hasConcept C2779858419 @default.
• W2065571723 hasConcept C2780950330 @default.
• W2065571723 hasConcept C2781263971 @default.
• W2065571723 hasConcept C2781401929 @default.
• W2065571723 hasConcept C2986274086 @default.
• W2065571723 hasConcept C31903555 @default.
• W2065571723 hasConcept C43617362 @default.
• W2065571723 hasConcept C4937899 @default.
• W2065571723 hasConcept C556039675 @default.
• W2065571723 hasConcept C71924100 @default.
• W2065571723 hasConcept C86803240 @default.
• W2065571723 hasConcept C97428945 @default.
• W2065571723 hasConceptScore W2065571723C144027150 @default.
• W2065571723 hasConceptScore W2065571723C176947019 @default.
• W2065571723 hasConceptScore W2065571723C178790620 @default.
• W2065571723 hasConceptScore W2065571723C185592680 @default.
• W2065571723 hasConceptScore W2065571723C2778004101 @default.
• W2065571723 hasConceptScore W2065571723C2778284287 @default.
• W2065571723 hasConceptScore W2065571723C2779054382 @default.
• W2065571723 hasConceptScore W2065571723C2779858419 @default.
• W2065571723 hasConceptScore W2065571723C2780950330 @default.
• W2065571723 hasConceptScore W2065571723C2781263971 @default.
• W2065571723 hasConceptScore W2065571723C2781401929 @default.
• W2065571723 hasConceptScore W2065571723C2986274086 @default.
• W2065571723 hasConceptScore W2065571723C31903555 @default.
• W2065571723 hasConceptScore W2065571723C43617362 @default.
• W2065571723 hasConceptScore W2065571723C4937899 @default.
• W2065571723 hasConceptScore W2065571723C556039675 @default.
• W2065571723 hasConceptScore W2065571723C71924100 @default.
• W2065571723 hasConceptScore W2065571723C86803240 @default.
• W2065571723 hasConceptScore W2065571723C97428945 @default.
• W2065571723 hasIssue "3" @default.

• next