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- W2065571888 abstract "The technology to simultaneously genotype hundreds of thousands of single nucleotide polymorphisms in a single assay has only recently been developed. These advances have the potential to revolutionize our ability to identify disease-associated proteins and their corresponding pathways as drugable targets. Several strategies that can take advantage of extremely high-density, genome-wide single nucleotide polymorphism genotyping to hone in on pathogenic genetic variants will be discussed. In familial linkage studies, high-density single nucleotide polymorphism genotyping has already been proven to speed up mutation identification of Mendelian traits several fold. Many studies now report examining loss of heterozygosity and genomic amplifications on a whole-genome level. Genotyping hundreds of thousands of single nucleotide polymorphisms in a single set of assays now also allows for whole-genome association studies in complex, multigenic diseases. The technology of high-density single nucleotide polymorphism genotyping has emerged rapidly, leaving data analysis and bioinformatic challenges only partially met. In this review, the immediate applications and implications of the rapidly changing high-density, whole-genome single nucleotide polymorphism genotyping field on translational research will be described." @default.
- W2065571888 created "2016-06-24" @default.
- W2065571888 creator A5060670463 @default.
- W2065571888 creator A5074460206 @default.
- W2065571888 date "2005-03-01" @default.
- W2065571888 modified "2023-09-30" @default.
- W2065571888 title "Applications of whole-genome high-density SNP genotyping" @default.
- W2065571888 cites W1522239197 @default.
- W2065571888 cites W1551600243 @default.
- W2065571888 cites W1583476286 @default.
- W2065571888 cites W1605691217 @default.
- W2065571888 cites W1958158305 @default.
- W2065571888 cites W1969114994 @default.
- W2065571888 cites W1969790498 @default.
- W2065571888 cites W1971692270 @default.
- W2065571888 cites W1974073207 @default.
- W2065571888 cites W1981642451 @default.
- W2065571888 cites W1982733535 @default.
- W2065571888 cites W1985682117 @default.
- W2065571888 cites W1985849948 @default.
- W2065571888 cites W1986265706 @default.
- W2065571888 cites W1987295193 @default.
- W2065571888 cites W1991311566 @default.
- W2065571888 cites W1991982209 @default.
- W2065571888 cites W1994130453 @default.
- W2065571888 cites W1996767070 @default.
- W2065571888 cites W1998158007 @default.
- W2065571888 cites W2001620383 @default.
- W2065571888 cites W2002637589 @default.
- W2065571888 cites W2004354911 @default.
- W2065571888 cites W2010595044 @default.
- W2065571888 cites W2013982997 @default.
- W2065571888 cites W2015248979 @default.
- W2065571888 cites W2015359315 @default.
- W2065571888 cites W2017376747 @default.
- W2065571888 cites W2023195692 @default.
- W2065571888 cites W2025306791 @default.
- W2065571888 cites W2030771667 @default.
- W2065571888 cites W2033041275 @default.
- W2065571888 cites W2036815268 @default.
- W2065571888 cites W2037509330 @default.
- W2065571888 cites W2041556087 @default.
- W2065571888 cites W2042103448 @default.
- W2065571888 cites W2044573154 @default.
- W2065571888 cites W2046317441 @default.
- W2065571888 cites W2050730569 @default.
- W2065571888 cites W2062252189 @default.
- W2065571888 cites W2065121811 @default.
- W2065571888 cites W2069107889 @default.
- W2065571888 cites W2069769149 @default.
- W2065571888 cites W2071199144 @default.
- W2065571888 cites W2071387002 @default.
- W2065571888 cites W2072134379 @default.
- W2065571888 cites W2079353636 @default.
- W2065571888 cites W2084115758 @default.
- W2065571888 cites W2093166014 @default.
- W2065571888 cites W2098126593 @default.
- W2065571888 cites W2098979053 @default.
- W2065571888 cites W2102058141 @default.
- W2065571888 cites W2102109283 @default.
- W2065571888 cites W2104241530 @default.
- W2065571888 cites W2105306382 @default.
- W2065571888 cites W2107889007 @default.
- W2065571888 cites W2107966042 @default.
- W2065571888 cites W2109178214 @default.
- W2065571888 cites W2110274174 @default.
- W2065571888 cites W2114044152 @default.
- W2065571888 cites W2117282939 @default.
- W2065571888 cites W2120547920 @default.
- W2065571888 cites W2122732537 @default.
- W2065571888 cites W2124277514 @default.
- W2065571888 cites W2125255775 @default.
- W2065571888 cites W2127230663 @default.
- W2065571888 cites W2127914534 @default.
- W2065571888 cites W2128481086 @default.
- W2065571888 cites W2132819133 @default.
- W2065571888 cites W2141042406 @default.
- W2065571888 cites W2141481588 @default.
- W2065571888 cites W2145025818 @default.
- W2065571888 cites W2152664025 @default.
- W2065571888 cites W2157080296 @default.
- W2065571888 cites W2168290824 @default.
- W2065571888 cites W2169022251 @default.
- W2065571888 cites W2221425513 @default.
- W2065571888 cites W2268513284 @default.
- W2065571888 cites W3003397968 @default.
- W2065571888 cites W4254301700 @default.
- W2065571888 cites W4319590830 @default.
- W2065571888 doi "https://doi.org/10.1586/14737159.5.2.159" @default.
- W2065571888 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15833046" @default.
- W2065571888 hasPublicationYear "2005" @default.
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