FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2065572140> ?p ?o ?g. }

• W2065572140 endingPage "316" @default.
• W2065572140 startingPage "309" @default.
• W2065572140 abstract "It is known that some metal salts can inhibit matrix metalloproteinase (MMP) activity, but the effect of iron has not been tested yet. On the other hand, it has recently been suggested that MMP inhibition might influence dentine erosion. Based on this, the aims of this study were: (1) to test in vitro the effect of FeSO(4) on MMP-2 and -9 activity, and (2) to evaluate in situ the effect of FeSO(4) gel on dentine erosion. MMP-2 and -9 activities were analysed zymographically in buffers containing FeSO(4) in concentrations ranging between 0.05 and 1.5 mmol/l or not. Volunteers (n = 10) wore devices containing bovine dentine blocks (n = 60) previously treated with the following gel treatments: FeSO(4) (1 mmol/l FeSO(4)), F (NaF 1.23%; positive control) and placebo (negative control). The gels were applied once and removed after 1 min. Erosion was performed extraorally with Coca-Cola 4 times per day for 5 min over 5 days. Dentine wear was evaluated by profilometry. The data were analysed by Kruskal-Wallis and Dunn's tests (p < 0.05). FeSO(4) inhibited both MMP-2 (IC(50) = 0.75 mmol/l) and MMP-9 (IC(50) = 0.50 mmol/l) activities. In the in situ experiment, the mean wear (+/- SD) found for the F gel (0.79 +/- 0.08 microm) was significantly reduced in more than 50% when compared to the placebo gel (1.77 +/- 0.33 microm), but the FeSO(4) gel completely inhibited the wear (0.05 +/- 0.02 mum). Since FeSO(4) was able to inhibit MMP in vitro, it is possible that the prevention of dentine wear by the FeSO(4) gel in situ might be due to MMP inhibition, which should be investigated in further studies." @default.
• W2065572140 created "2016-06-24" @default.
• W2065572140 creator A5005918121 @default.
• W2065572140 creator A5025646534 @default.
• W2065572140 creator A5025698678 @default.
• W2065572140 creator A5044582813 @default.
• W2065572140 creator A5053800999 @default.
• W2065572140 creator A5067222700 @default.
• W2065572140 creator A5076470455 @default.
• W2065572140 date "2010-01-01" @default.
• W2065572140 modified "2023-10-01" @default.
• W2065572140 title "Effect of Iron on Matrix Metalloproteinase Inhibition and on the Prevention of Dentine Erosion" @default.
• W2065572140 cites W1964682327 @default.
• W2065572140 cites W1966027638 @default.
• W2065572140 cites W1974886190 @default.
• W2065572140 cites W1987382000 @default.
• W2065572140 cites W2005396743 @default.
• W2065572140 cites W2012729708 @default.
• W2065572140 cites W2026004262 @default.
• W2065572140 cites W2034352690 @default.
• W2065572140 cites W2034752268 @default.
• W2065572140 cites W2036133721 @default.
• W2065572140 cites W2040531719 @default.
• W2065572140 cites W2047082457 @default.
• W2065572140 cites W2055843721 @default.
• W2065572140 cites W2058131840 @default.
• W2065572140 cites W2059304811 @default.
• W2065572140 cites W2076396405 @default.
• W2065572140 cites W2077555123 @default.
• W2065572140 cites W2082240384 @default.
• W2065572140 cites W2085111673 @default.
• W2065572140 cites W2085976916 @default.
• W2065572140 cites W2088244067 @default.
• W2065572140 cites W2099966737 @default.
• W2065572140 cites W2110069428 @default.
• W2065572140 cites W2114463608 @default.
• W2065572140 cites W2133294732 @default.
• W2065572140 cites W2134865618 @default.
• W2065572140 cites W2144551409 @default.
• W2065572140 cites W2152372206 @default.
• W2065572140 cites W2168920694 @default.
• W2065572140 cites W2946488594 @default.
• W2065572140 cites W48986552 @default.
• W2065572140 doi "https://doi.org/10.1159/000315932" @default.
• W2065572140 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20551644" @default.
• W2065572140 hasPublicationYear "2010" @default.
• W2065572140 type Work @default.
• W2065572140 sameAs 2065572140 @default.
• W2065572140 citedByCount "48" @default.
• W2065572140 countsByYear W20655721402012 @default.
• W2065572140 countsByYear W20655721402013 @default.
• W2065572140 countsByYear W20655721402014 @default.
• W2065572140 countsByYear W20655721402015 @default.
• W2065572140 countsByYear W20655721402016 @default.
• W2065572140 countsByYear W20655721402017 @default.
• W2065572140 countsByYear W20655721402018 @default.
• W2065572140 countsByYear W20655721402019 @default.
• W2065572140 countsByYear W20655721402020 @default.
• W2065572140 countsByYear W20655721402021 @default.
• W2065572140 countsByYear W20655721402022 @default.
• W2065572140 countsByYear W20655721402023 @default.
• W2065572140 crossrefType "journal-article" @default.
• W2065572140 hasAuthorship W2065572140A5005918121 @default.
• W2065572140 hasAuthorship W2065572140A5025646534 @default.
• W2065572140 hasAuthorship W2065572140A5025698678 @default.
• W2065572140 hasAuthorship W2065572140A5044582813 @default.
• W2065572140 hasAuthorship W2065572140A5053800999 @default.
• W2065572140 hasAuthorship W2065572140A5067222700 @default.
• W2065572140 hasAuthorship W2065572140A5076470455 @default.
• W2065572140 hasConcept C106487976 @default.
• W2065572140 hasConcept C109523444 @default.
• W2065572140 hasConcept C13965031 @default.
• W2065572140 hasConcept C142724271 @default.
• W2065572140 hasConcept C185592680 @default.
• W2065572140 hasConcept C199343813 @default.
• W2065572140 hasConcept C204787440 @default.
• W2065572140 hasConcept C27081682 @default.
• W2065572140 hasConcept C3018223157 @default.
• W2065572140 hasConcept C3019361144 @default.
• W2065572140 hasConcept C43617362 @default.
• W2065572140 hasConcept C55493867 @default.
• W2065572140 hasConcept C556039675 @default.
• W2065572140 hasConcept C71924100 @default.
• W2065572140 hasConceptScore W2065572140C106487976 @default.
• W2065572140 hasConceptScore W2065572140C109523444 @default.
• W2065572140 hasConceptScore W2065572140C13965031 @default.
• W2065572140 hasConceptScore W2065572140C142724271 @default.
• W2065572140 hasConceptScore W2065572140C185592680 @default.
• W2065572140 hasConceptScore W2065572140C199343813 @default.
• W2065572140 hasConceptScore W2065572140C204787440 @default.
• W2065572140 hasConceptScore W2065572140C27081682 @default.
• W2065572140 hasConceptScore W2065572140C3018223157 @default.
• W2065572140 hasConceptScore W2065572140C3019361144 @default.
• W2065572140 hasConceptScore W2065572140C43617362 @default.
• W2065572140 hasConceptScore W2065572140C55493867 @default.
• W2065572140 hasConceptScore W2065572140C556039675 @default.
• W2065572140 hasConceptScore W2065572140C71924100 @default.
• W2065572140 hasIssue "3" @default.

• next