Matches in SemOpenAlex for { <https://semopenalex.org/work/W2065575338> ?p ?o ?g. }
- W2065575338 endingPage "416" @default.
- W2065575338 startingPage "409" @default.
- W2065575338 abstract "Carbon nanomaterials, such as single-walled carbon nanohorns (SWCNHs) and carbon nanotubes, demonstrate great potential as drug delivery systems. However, no reports to date have detailed the use of SWCNHs as oral drug carriers. This study shows for the first time the actions of orally-administered SWCNHs in normal mice and mice with dextran sulfate sodium (DSS)-induced colitis. SWCNHs labeled with gadolinium oxide for quantification purposes were detected in the gastrointestinal tract and the feces of mice, but not in the blood or other bodily organs. These results indicate that the nanohorns were not absorbed into the body from the gastrointestinal tract. SWCNH absorption was not influenced by the functionalization or size control of SWCNH. Neither death nor behavioral aberrations were observed in normal mice following SWCNH administration. However, histological observation of mice with DSS-induced colitis at 24 h after oral administration of SWCNHs revealed the presence of black particles, presumed to be SWCNHs, in the inflamed areas of the colon and the cecum. Thus, SWCNHs might serve as efficacious drug delivery carriers for the treatment of ulcerative colitis." @default.
- W2065575338 created "2016-06-24" @default.
- W2065575338 creator A5008059619 @default.
- W2065575338 creator A5058498412 @default.
- W2065575338 creator A5063774507 @default.
- W2065575338 creator A5079604706 @default.
- W2065575338 creator A5079749826 @default.
- W2065575338 date "2014-04-01" @default.
- W2065575338 modified "2023-10-09" @default.
- W2065575338 title "Gastrointestinal actions of orally-administered single-walled carbon nanohorns" @default.
- W2065575338 cites W1971290741 @default.
- W2065575338 cites W1975716763 @default.
- W2065575338 cites W1982372788 @default.
- W2065575338 cites W1982554116 @default.
- W2065575338 cites W1984458677 @default.
- W2065575338 cites W1985947805 @default.
- W2065575338 cites W1988658785 @default.
- W2065575338 cites W1996402722 @default.
- W2065575338 cites W2004606548 @default.
- W2065575338 cites W2006425566 @default.
- W2065575338 cites W2006890570 @default.
- W2065575338 cites W2008928282 @default.
- W2065575338 cites W2010265091 @default.
- W2065575338 cites W2012904684 @default.
- W2065575338 cites W2016285138 @default.
- W2065575338 cites W2018858346 @default.
- W2065575338 cites W2021083732 @default.
- W2065575338 cites W2022047303 @default.
- W2065575338 cites W2028203326 @default.
- W2065575338 cites W2028244878 @default.
- W2065575338 cites W2046251407 @default.
- W2065575338 cites W2049712793 @default.
- W2065575338 cites W2050220640 @default.
- W2065575338 cites W2054889335 @default.
- W2065575338 cites W2060169338 @default.
- W2065575338 cites W2076699674 @default.
- W2065575338 cites W2082904789 @default.
- W2065575338 cites W2088614204 @default.
- W2065575338 cites W2091205241 @default.
- W2065575338 cites W2097466192 @default.
- W2065575338 cites W2098565706 @default.
- W2065575338 cites W2107425135 @default.
- W2065575338 cites W2109165172 @default.
- W2065575338 cites W2110166605 @default.
- W2065575338 cites W2121342567 @default.
- W2065575338 cites W2138003976 @default.
- W2065575338 cites W2152429732 @default.
- W2065575338 cites W2170542143 @default.
- W2065575338 cites W2335600781 @default.
- W2065575338 doi "https://doi.org/10.1016/j.carbon.2013.12.043" @default.
- W2065575338 hasPublicationYear "2014" @default.
- W2065575338 type Work @default.
- W2065575338 sameAs 2065575338 @default.
- W2065575338 citedByCount "16" @default.
- W2065575338 countsByYear W20655753382014 @default.
- W2065575338 countsByYear W20655753382015 @default.
- W2065575338 countsByYear W20655753382016 @default.
- W2065575338 countsByYear W20655753382017 @default.
- W2065575338 countsByYear W20655753382020 @default.
- W2065575338 countsByYear W20655753382021 @default.
- W2065575338 countsByYear W20655753382022 @default.
- W2065575338 countsByYear W20655753382023 @default.
- W2065575338 crossrefType "journal-article" @default.
- W2065575338 hasAuthorship W2065575338A5008059619 @default.
- W2065575338 hasAuthorship W2065575338A5058498412 @default.
- W2065575338 hasAuthorship W2065575338A5063774507 @default.
- W2065575338 hasAuthorship W2065575338A5079604706 @default.
- W2065575338 hasAuthorship W2065575338A5079749826 @default.
- W2065575338 hasConcept C125287762 @default.
- W2065575338 hasConcept C126322002 @default.
- W2065575338 hasConcept C159985019 @default.
- W2065575338 hasConcept C171250308 @default.
- W2065575338 hasConcept C192562407 @default.
- W2065575338 hasConcept C2777056448 @default.
- W2065575338 hasConcept C2777507495 @default.
- W2065575338 hasConcept C2779134260 @default.
- W2065575338 hasConcept C2779820397 @default.
- W2065575338 hasConcept C2780035454 @default.
- W2065575338 hasConcept C2780479503 @default.
- W2065575338 hasConcept C2780512811 @default.
- W2065575338 hasConcept C71924100 @default.
- W2065575338 hasConcept C98274493 @default.
- W2065575338 hasConceptScore W2065575338C125287762 @default.
- W2065575338 hasConceptScore W2065575338C126322002 @default.
- W2065575338 hasConceptScore W2065575338C159985019 @default.
- W2065575338 hasConceptScore W2065575338C171250308 @default.
- W2065575338 hasConceptScore W2065575338C192562407 @default.
- W2065575338 hasConceptScore W2065575338C2777056448 @default.
- W2065575338 hasConceptScore W2065575338C2777507495 @default.
- W2065575338 hasConceptScore W2065575338C2779134260 @default.
- W2065575338 hasConceptScore W2065575338C2779820397 @default.
- W2065575338 hasConceptScore W2065575338C2780035454 @default.
- W2065575338 hasConceptScore W2065575338C2780479503 @default.
- W2065575338 hasConceptScore W2065575338C2780512811 @default.
- W2065575338 hasConceptScore W2065575338C71924100 @default.
- W2065575338 hasConceptScore W2065575338C98274493 @default.
- W2065575338 hasFunder F4320334764 @default.
- W2065575338 hasLocation W20655753381 @default.