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- W2065586977 endingPage "636" @default.
- W2065586977 startingPage "629" @default.
- W2065586977 abstract "Iron is an essential element for life, as it is a cofactor for enzymes involved in many metabolic processes, but it can also be harmful, since its excess is thought to enhance the production of reactive oxygen species and induce oxidative damage. Iron is transformed into its biologically available form in the mitochondrion by the iron-sulfur (Fe/S) cluster and heme synthesis pathways. During the past decade, substantial progress has been made in the elucidation of iron-linked mechanisms that occur in the mitochondrion, demonstrating the crucial role played by this organelle in maintaining cellular iron homeostasis.This review summarizes current knowledge of the mechanisms underlying iron trafficking in mitochondria and how it is handled inside the organelle. Relevant updates with regard to the Fe/S cluster and heme biosynthetic pathways, as well as the relationship between mitochondrial iron homeostasis impairment and related diseases, are also discussed." @default.
- W2065586977 created "2016-06-24" @default.
- W2065586977 creator A5050840680 @default.
- W2065586977 creator A5061524046 @default.
- W2065586977 date "2009-07-01" @default.
- W2065586977 modified "2023-10-18" @default.
- W2065586977 title "The role of iron in mitochondrial function" @default.
- W2065586977 cites W1484379620 @default.
- W2065586977 cites W151933253 @default.
- W2065586977 cites W1526693931 @default.
- W2065586977 cites W1602264642 @default.
- W2065586977 cites W1719677165 @default.
- W2065586977 cites W1966469827 @default.
- W2065586977 cites W1968097249 @default.
- W2065586977 cites W1968251654 @default.
- W2065586977 cites W1972998779 @default.
- W2065586977 cites W1977013265 @default.
- W2065586977 cites W1977203945 @default.
- W2065586977 cites W1978004953 @default.
- W2065586977 cites W1981634932 @default.
- W2065586977 cites W1983737836 @default.
- W2065586977 cites W1992193197 @default.
- W2065586977 cites W1992222348 @default.
- W2065586977 cites W1993743888 @default.
- W2065586977 cites W1997684705 @default.
- W2065586977 cites W1998351143 @default.
- W2065586977 cites W1998658081 @default.
- W2065586977 cites W1999714394 @default.
- W2065586977 cites W2002390714 @default.
- W2065586977 cites W2003418336 @default.
- W2065586977 cites W2006383772 @default.
- W2065586977 cites W2006756678 @default.
- W2065586977 cites W2008326745 @default.
- W2065586977 cites W2009029742 @default.
- W2065586977 cites W2011048815 @default.
- W2065586977 cites W2016472363 @default.
- W2065586977 cites W2016750393 @default.
- W2065586977 cites W2019073080 @default.
- W2065586977 cites W2019160673 @default.
- W2065586977 cites W2022751993 @default.
- W2065586977 cites W2024089487 @default.
- W2065586977 cites W2025348458 @default.
- W2065586977 cites W2025906616 @default.
- W2065586977 cites W2027313575 @default.
- W2065586977 cites W2029342749 @default.
- W2065586977 cites W2030356875 @default.
- W2065586977 cites W2030548279 @default.
- W2065586977 cites W2031508994 @default.
- W2065586977 cites W2031715536 @default.
- W2065586977 cites W2031942239 @default.
- W2065586977 cites W2035312624 @default.
- W2065586977 cites W2035410822 @default.
- W2065586977 cites W2039280518 @default.
- W2065586977 cites W2039561552 @default.
- W2065586977 cites W2040239256 @default.
- W2065586977 cites W2041508675 @default.
- W2065586977 cites W2043541600 @default.
- W2065586977 cites W2045143928 @default.
- W2065586977 cites W2045830695 @default.
- W2065586977 cites W2047841749 @default.
- W2065586977 cites W2048245347 @default.
- W2065586977 cites W2048847466 @default.
- W2065586977 cites W2049009393 @default.
- W2065586977 cites W2049031192 @default.
- W2065586977 cites W2050448306 @default.
- W2065586977 cites W2051279372 @default.
- W2065586977 cites W2055981765 @default.
- W2065586977 cites W2057404038 @default.
- W2065586977 cites W2063616227 @default.
- W2065586977 cites W2063623087 @default.
- W2065586977 cites W2069849662 @default.
- W2065586977 cites W2071219983 @default.
- W2065586977 cites W2072442925 @default.
- W2065586977 cites W2073746011 @default.
- W2065586977 cites W2075400482 @default.
- W2065586977 cites W2077687448 @default.
- W2065586977 cites W2078339670 @default.
- W2065586977 cites W2078448486 @default.
- W2065586977 cites W2079075712 @default.
- W2065586977 cites W2079314569 @default.
- W2065586977 cites W2079530305 @default.
- W2065586977 cites W2081936723 @default.
- W2065586977 cites W2088404957 @default.
- W2065586977 cites W2090079874 @default.
- W2065586977 cites W2090154662 @default.
- W2065586977 cites W2091830321 @default.
- W2065586977 cites W2092224500 @default.
- W2065586977 cites W2095232221 @default.
- W2065586977 cites W2096692378 @default.
- W2065586977 cites W2098498940 @default.
- W2065586977 cites W2100394721 @default.
- W2065586977 cites W2102144538 @default.
- W2065586977 cites W2106360060 @default.
- W2065586977 cites W2107386134 @default.
- W2065586977 cites W2110649328 @default.
- W2065586977 cites W2111599402 @default.
- W2065586977 cites W2114484640 @default.
- W2065586977 cites W2114814810 @default.