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- W2065618952 abstract "Of 10479 singleton pregnancies in South Glamorgan between January 1974 and June 1976, 27.3% occurred in women who had used oral contraceptives in the 3 months prior to their last menstrual period (users) and 72.7% occurred in women who had not used oral contraception during the same period (non-users). Significantly more users gained weight excessively. Oral contraceptive use increased the likelihood of uncertain dates and post-maturity. The incidence of neural tube defects was higher among children born to users, although the overall perinatal outcome was not adversely affected. The sex distribution of the offspring was the same in both groups.2859 (27.3%) of the 10,479 singleton pregnancies registered in South Glamorgan, Wales, between January 1974 and June 1976 occurred in women who had used oral contraceptives (OCs) in the 3 months prior to their last menstrual period. Excessive weight gain during pregnancy was documented in 499 (25%) of the OC users compared to 1391 (23%) of nonusers--a significant difference. 20% of OC users versus 18% of nonusers had uncertain gestational dates. The perinatal death rate was not significantly different--16/1000 births among OC users and 17/1000 among nonusers. However, the incidence of neural tube defects was significantly higher among users (0.63%) than among nonusers (0.25%). Finally, there was no significant difference between the 2 groups in mean birthweight and the sex of the infant was not affected by OC use. Overall, these findings fail to document any significant deleterious effects of OC use immediately before pregnancy. However, a pill-free interval is recommended prior to allow the menstrual cycle to return to normal so that gestation can be assessed accurately." @default.
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- W2065618952 date "1986-06-01" @default.
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- W2065618952 title "The effects of recent oral contraceptive use on the outcome of pregnancy" @default.
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- W2065618952 doi "https://doi.org/10.1016/0028-2243(86)90092-4" @default.
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