Matches in SemOpenAlex for { <https://semopenalex.org/work/W2065661192> ?p ?o ?g. }
- W2065661192 endingPage "5424" @default.
- W2065661192 startingPage "5417" @default.
- W2065661192 abstract "Cervical cancer is found to be associated with human papillomavirus (HPV) infection, with HPV16 being the most prevalent. An effective vaccine against HPV can thus, be instrumental in controlling cervical cancer. An ideal HPV vaccine should aim to generate both humoral immune response to prevent new infection as well as cell-mediated immunity to eliminate established infection. In this study, we have generated a potential preventive and therapeutic candidate vaccine against HPV16. We expressed and purified recombinant HPV16 L1ΔN26–E7ΔC38 protein in E. coli which was assembled into chimeric virus like particles (CVLPs) in vitro. These CVLPs were able to induce neutralizing antibodies and trigger cell-mediated immune response, in murine model of cervical cancer, exhibiting antitumor efficacy. Hence, this study has aimed to provide a vaccine candidate possessing both, prophylactic and therapeutic efficacy against HPV16 associated cervical cancer." @default.
- W2065661192 created "2016-06-24" @default.
- W2065661192 creator A5002686740 @default.
- W2065661192 creator A5012188202 @default.
- W2065661192 creator A5014094479 @default.
- W2065661192 creator A5014637548 @default.
- W2065661192 date "2012-08-01" @default.
- W2065661192 modified "2023-10-16" @default.
- W2065661192 title "Human papillomavirus 16 L1–E7 chimeric virus like particles show prophylactic and therapeutic efficacy in murine model of cervical cancer" @default.
- W2065661192 cites W1488126231 @default.
- W2065661192 cites W1541731964 @default.
- W2065661192 cites W1775152191 @default.
- W2065661192 cites W1807715620 @default.
- W2065661192 cites W1967939624 @default.
- W2065661192 cites W1978146796 @default.
- W2065661192 cites W1983494331 @default.
- W2065661192 cites W1990068438 @default.
- W2065661192 cites W1990794690 @default.
- W2065661192 cites W2000801374 @default.
- W2065661192 cites W2006070802 @default.
- W2065661192 cites W2010848574 @default.
- W2065661192 cites W2011724423 @default.
- W2065661192 cites W2014353718 @default.
- W2065661192 cites W2032128657 @default.
- W2065661192 cites W2035185947 @default.
- W2065661192 cites W2044938790 @default.
- W2065661192 cites W2049095033 @default.
- W2065661192 cites W2051461779 @default.
- W2065661192 cites W2055415515 @default.
- W2065661192 cites W2056656100 @default.
- W2065661192 cites W2068189504 @default.
- W2065661192 cites W2071854592 @default.
- W2065661192 cites W2076240146 @default.
- W2065661192 cites W2077403314 @default.
- W2065661192 cites W2078621642 @default.
- W2065661192 cites W2083182154 @default.
- W2065661192 cites W2089899954 @default.
- W2065661192 cites W2095903414 @default.
- W2065661192 cites W2098765233 @default.
- W2065661192 cites W2114918609 @default.
- W2065661192 cites W2117683895 @default.
- W2065661192 cites W2117995803 @default.
- W2065661192 cites W2132910427 @default.
- W2065661192 cites W2136236728 @default.
- W2065661192 cites W2144359412 @default.
- W2065661192 cites W2164496839 @default.
- W2065661192 cites W2165069156 @default.
- W2065661192 cites W2168690984 @default.
- W2065661192 cites W3102641294 @default.
- W2065661192 doi "https://doi.org/10.1016/j.vaccine.2012.06.010" @default.
- W2065661192 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22717329" @default.
- W2065661192 hasPublicationYear "2012" @default.
- W2065661192 type Work @default.
- W2065661192 sameAs 2065661192 @default.
- W2065661192 citedByCount "18" @default.
- W2065661192 countsByYear W20656611922013 @default.
- W2065661192 countsByYear W20656611922014 @default.
- W2065661192 countsByYear W20656611922015 @default.
- W2065661192 countsByYear W20656611922017 @default.
- W2065661192 countsByYear W20656611922019 @default.
- W2065661192 countsByYear W20656611922023 @default.
- W2065661192 crossrefType "journal-article" @default.
- W2065661192 hasAuthorship W2065661192A5002686740 @default.
- W2065661192 hasAuthorship W2065661192A5012188202 @default.
- W2065661192 hasAuthorship W2065661192A5014094479 @default.
- W2065661192 hasAuthorship W2065661192A5014637548 @default.
- W2065661192 hasConcept C121608353 @default.
- W2065661192 hasConcept C126322002 @default.
- W2065661192 hasConcept C159047783 @default.
- W2065661192 hasConcept C159654299 @default.
- W2065661192 hasConcept C203014093 @default.
- W2065661192 hasConcept C22070199 @default.
- W2065661192 hasConcept C2522874641 @default.
- W2065661192 hasConcept C2776548049 @default.
- W2065661192 hasConcept C2778220009 @default.
- W2065661192 hasConcept C2779341262 @default.
- W2065661192 hasConcept C502942594 @default.
- W2065661192 hasConcept C71924100 @default.
- W2065661192 hasConcept C86803240 @default.
- W2065661192 hasConcept C8891405 @default.
- W2065661192 hasConceptScore W2065661192C121608353 @default.
- W2065661192 hasConceptScore W2065661192C126322002 @default.
- W2065661192 hasConceptScore W2065661192C159047783 @default.
- W2065661192 hasConceptScore W2065661192C159654299 @default.
- W2065661192 hasConceptScore W2065661192C203014093 @default.
- W2065661192 hasConceptScore W2065661192C22070199 @default.
- W2065661192 hasConceptScore W2065661192C2522874641 @default.
- W2065661192 hasConceptScore W2065661192C2776548049 @default.
- W2065661192 hasConceptScore W2065661192C2778220009 @default.
- W2065661192 hasConceptScore W2065661192C2779341262 @default.
- W2065661192 hasConceptScore W2065661192C502942594 @default.
- W2065661192 hasConceptScore W2065661192C71924100 @default.
- W2065661192 hasConceptScore W2065661192C86803240 @default.
- W2065661192 hasConceptScore W2065661192C8891405 @default.
- W2065661192 hasFunder F4320326656 @default.
- W2065661192 hasIssue "36" @default.
- W2065661192 hasLocation W20656611921 @default.
- W2065661192 hasLocation W20656611922 @default.