FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2065688518> ?p ?o ?g. }

• W2065688518 endingPage "937" @default.
• W2065688518 startingPage "931" @default.
• W2065688518 abstract "Although methohexital has been well studied for use in emergency department (ED) procedural sedation (PS), propofol has been evaluated less extensively for ED use. Objective: The authors hypothesized that there is no difference in the depth of sedation and the rate of respiratory depression (RD) between propofol and methohexital in PS during the reduction of fractures and dislocations in the ED. Methods: This was a randomized prospective study of nonintoxicated adult patients undergoing PS for fracture or dislocation reduction in the ED between July 2001 and March 2002. Patients were randomized to receive either propofol or methohexital, 1 mg/kg intravenously, followed by repeat boluses of 0.5 mg/kg every 2 minutes until adequate sedation was achieved. Doses, vital signs, end-tidal CO 2 (ETCO 2) by nasal cannulae, pulse oximetry, and bispectral electroencephalogram analysis (BIS) scores were recorded. RD was defined as an ETCO 2 greater than 50 torr, an oxygen saturation less than 90% at any time, or an absent ETCO 2 waveform. After returning to baseline mental status, patients completed three 100-mm visual analog scales (VASs) regarding pain associated with the procedure, recall of the procedure, and satisfaction. RD rates and VAS outcomes were compared with chi-square tests. Results: There were 109 patients enrolled; six were excluded for study protocol violations. Of the remaining 103 patients, 52 received methohexital (reduction successful in 94%) and 51 received propofol (98% successful). No cardiac rhythm abnormalities or significant decline in systolic blood pressure (>20%) was detected. Six patients required bag-valve-mask-assisted ventilations during the procedure, all for less than 1 minute; four of these patients received methohexital, and two received propofol. By the authors' definition, RD was seen in 25 of 52 (48%) patients receiving methohexital and 25 of 51 (49%) patients receiving propofol (p = 0.88). The mean minimum recorded BIS score was 66.2 (95% confidence interval [CI] = 62 to 70) for methohexital and 66 (95% CI = 60 to 71) for propofol. VAS results showed similar rates of reported pain, recall, and satisfaction for the two agents. Conclusions: The authors were unable to detect a significant difference in the level of subclinical RD or the level of sedation by BIS between the two agents. The use of either agent seems to be safe in the ED." @default.
• W2065688518 created "2016-06-24" @default.
• W2065688518 creator A5029702979 @default.
• W2065688518 creator A5060919122 @default.
• W2065688518 creator A5075900301 @default.
• W2065688518 creator A5076389841 @default.
• W2065688518 creator A5087582932 @default.
• W2065688518 creator A5089886498 @default.
• W2065688518 date "2003-09-01" @default.
• W2065688518 modified "2023-10-02" @default.
• W2065688518 title "Randomized Clinical Trial of Propofol versus Methohexital for Procedural Sedation during Fracture and Dislocation Reduction in the Emergency Department" @default.
• W2065688518 cites W190441754 @default.
• W2065688518 cites W1990929229 @default.
• W2065688518 cites W1993701358 @default.
• W2065688518 cites W1995454293 @default.
• W2065688518 cites W1996563991 @default.
• W2065688518 cites W2002254780 @default.
• W2065688518 cites W2014406350 @default.
• W2065688518 cites W2015469088 @default.
• W2065688518 cites W2025499314 @default.
• W2065688518 cites W2029696555 @default.
• W2065688518 cites W2043669389 @default.
• W2065688518 cites W2045805173 @default.
• W2065688518 cites W2047362382 @default.
• W2065688518 cites W2049289092 @default.
• W2065688518 cites W2068138921 @default.
• W2065688518 cites W2072801512 @default.
• W2065688518 cites W2074396726 @default.
• W2065688518 cites W2075074900 @default.
• W2065688518 cites W2082574732 @default.
• W2065688518 cites W2083343637 @default.
• W2065688518 cites W2128643063 @default.
• W2065688518 cites W2139255073 @default.
• W2065688518 cites W2318822860 @default.
• W2065688518 cites W2408021927 @default.
• W2065688518 cites W2470268090 @default.
• W2065688518 cites W1784084202 @default.
• W2065688518 doi "https://doi.org/10.1197/s1069-6563(03)00310-5" @default.
• W2065688518 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12957974" @default.
• W2065688518 hasPublicationYear "2003" @default.
• W2065688518 type Work @default.
• W2065688518 sameAs 2065688518 @default.
• W2065688518 citedByCount "61" @default.
• W2065688518 countsByYear W20656885182012 @default.
• W2065688518 countsByYear W20656885182013 @default.
• W2065688518 countsByYear W20656885182014 @default.
• W2065688518 countsByYear W20656885182015 @default.
• W2065688518 countsByYear W20656885182016 @default.
• W2065688518 countsByYear W20656885182017 @default.
• W2065688518 countsByYear W20656885182018 @default.
• W2065688518 countsByYear W20656885182019 @default.
• W2065688518 countsByYear W20656885182020 @default.
• W2065688518 countsByYear W20656885182021 @default.
• W2065688518 countsByYear W20656885182022 @default.
• W2065688518 countsByYear W20656885182023 @default.
• W2065688518 crossrefType "journal-article" @default.
• W2065688518 hasAuthorship W2065688518A5029702979 @default.
• W2065688518 hasAuthorship W2065688518A5060919122 @default.
• W2065688518 hasAuthorship W2065688518A5075900301 @default.
• W2065688518 hasAuthorship W2065688518A5076389841 @default.
• W2065688518 hasAuthorship W2065688518A5087582932 @default.
• W2065688518 hasAuthorship W2065688518A5089886498 @default.
• W2065688518 hasBestOaLocation W20656885181 @default.
• W2065688518 hasConcept C118552586 @default.
• W2065688518 hasConcept C126322002 @default.
• W2065688518 hasConcept C141071460 @default.
• W2065688518 hasConcept C168563851 @default.
• W2065688518 hasConcept C2776277131 @default.
• W2065688518 hasConcept C2776814716 @default.
• W2065688518 hasConcept C2777260365 @default.
• W2065688518 hasConcept C2780724011 @default.
• W2065688518 hasConcept C42219234 @default.
• W2065688518 hasConcept C71924100 @default.
• W2065688518 hasConcept C84393581 @default.
• W2065688518 hasConceptScore W2065688518C118552586 @default.
• W2065688518 hasConceptScore W2065688518C126322002 @default.
• W2065688518 hasConceptScore W2065688518C141071460 @default.
• W2065688518 hasConceptScore W2065688518C168563851 @default.
• W2065688518 hasConceptScore W2065688518C2776277131 @default.
• W2065688518 hasConceptScore W2065688518C2776814716 @default.
• W2065688518 hasConceptScore W2065688518C2777260365 @default.
• W2065688518 hasConceptScore W2065688518C2780724011 @default.
• W2065688518 hasConceptScore W2065688518C42219234 @default.
• W2065688518 hasConceptScore W2065688518C71924100 @default.
• W2065688518 hasConceptScore W2065688518C84393581 @default.
• W2065688518 hasIssue "9" @default.
• W2065688518 hasLocation W20656885181 @default.
• W2065688518 hasOpenAccess W2065688518 @default.
• W2065688518 hasPrimaryLocation W20656885181 @default.
• W2065688518 hasRelatedWork W163357817 @default.
• W2065688518 hasRelatedWork W1985198936 @default.
• W2065688518 hasRelatedWork W2001683931 @default.
• W2065688518 hasRelatedWork W2025085996 @default.
• W2065688518 hasRelatedWork W2085712438 @default.
• W2065688518 hasRelatedWork W2116124193 @default.
• W2065688518 hasRelatedWork W2373888550 @default.
• W2065688518 hasRelatedWork W4242342464 @default.
• W2065688518 hasRelatedWork W67055460 @default.

• next