FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2065691470> ?p ?o ?g. }

• W2065691470 endingPage "31" @default.
• W2065691470 startingPage "25" @default.
• W2065691470 abstract "Cell-cycle-related proteins, such as cyclins or cyclin-dependent kinases, are re-expressed in neurons committed to death in response to a variety of insults, including excitotoxins, hypoxia and ischemia, loss of trophic support, or beta-amyloid peptide. In some of these conditions events that are typical of the mid-G1 phase, such as cyclin-dependent kinase 4/6 activation, are required for the induction of neuronal death. In other cases, the cycle must proceed further and recruit steps that are typical of the G1/S transition for death to occur. Finally, there are conditions in which cell-cycle proteins might be re-expressed, but do not contribute to neuronal death. We hypothesize that cell-cycle signaling becomes a mandatory component of neuronal demise when other mechanisms are not enough for neurons to reach the threshold for death. Under this scheme, the death threshold is set by the extent of DNA damage. Whenever the extent of DNA damage is below this threshold, a cell-cycle signaling becomes crucial for the induction of neuronal death through p53-dependent or -independent pathways." @default.
• W2065691470 created "2016-06-24" @default.
• W2065691470 creator A5033485888 @default.
• W2065691470 creator A5056468131 @default.
• W2065691470 creator A5062403608 @default.
• W2065691470 creator A5075738977 @default.
• W2065691470 creator A5079505297 @default.
• W2065691470 creator A5082099245 @default.
• W2065691470 date "2001-01-01" @default.
• W2065691470 modified "2023-09-29" @default.
• W2065691470 title "Activation of cell-cycle-associated proteins in neuronal death: a mandatory or dispensable path?" @default.
• W2065691470 cites W1577877616 @default.
• W2065691470 cites W1609607086 @default.
• W2065691470 cites W1646788158 @default.
• W2065691470 cites W1888982058 @default.
• W2065691470 cites W1893523030 @default.
• W2065691470 cites W1920883260 @default.
• W2065691470 cites W1939092506 @default.
• W2065691470 cites W1969523279 @default.
• W2065691470 cites W1969995067 @default.
• W2065691470 cites W1970458627 @default.
• W2065691470 cites W1972047666 @default.
• W2065691470 cites W1977632821 @default.
• W2065691470 cites W1981105329 @default.
• W2065691470 cites W1985208032 @default.
• W2065691470 cites W1990168632 @default.
• W2065691470 cites W1990188518 @default.
• W2065691470 cites W1995276486 @default.
• W2065691470 cites W2001159408 @default.
• W2065691470 cites W2001213818 @default.
• W2065691470 cites W2001627329 @default.
• W2065691470 cites W2002324371 @default.
• W2065691470 cites W2002397068 @default.
• W2065691470 cites W2005849137 @default.
• W2065691470 cites W2010449169 @default.
• W2065691470 cites W2013009825 @default.
• W2065691470 cites W2023531011 @default.
• W2065691470 cites W2026903687 @default.
• W2065691470 cites W2030047809 @default.
• W2065691470 cites W2030246777 @default.
• W2065691470 cites W2031595027 @default.
• W2065691470 cites W2032770280 @default.
• W2065691470 cites W2034792033 @default.
• W2065691470 cites W2036142609 @default.
• W2065691470 cites W2043191368 @default.
• W2065691470 cites W2043858822 @default.
• W2065691470 cites W2044131670 @default.
• W2065691470 cites W2047254990 @default.
• W2065691470 cites W2058646495 @default.
• W2065691470 cites W2059328439 @default.
• W2065691470 cites W2060810889 @default.
• W2065691470 cites W2067518219 @default.
• W2065691470 cites W2068870278 @default.
• W2065691470 cites W2074579300 @default.
• W2065691470 cites W2076409812 @default.
• W2065691470 cites W2078106239 @default.
• W2065691470 cites W2079174302 @default.
• W2065691470 cites W2086825397 @default.
• W2065691470 cites W2107805271 @default.
• W2065691470 cites W2111020015 @default.
• W2065691470 cites W2115093096 @default.
• W2065691470 cites W2123297155 @default.
• W2065691470 cites W2126517273 @default.
• W2065691470 cites W2130118447 @default.
• W2065691470 cites W2141487162 @default.
• W2065691470 cites W2144983731 @default.
• W2065691470 cites W2148958834 @default.
• W2065691470 cites W2316424201 @default.
• W2065691470 cites W2329132780 @default.
• W2065691470 cites W2151855867 @default.
• W2065691470 doi "https://doi.org/10.1016/s0166-2236(00)01663-5" @default.
• W2065691470 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11163884" @default.
• W2065691470 hasPublicationYear "2001" @default.
• W2065691470 type Work @default.
• W2065691470 sameAs 2065691470 @default.
• W2065691470 citedByCount "220" @default.
• W2065691470 countsByYear W20656914702012 @default.
• W2065691470 countsByYear W20656914702013 @default.
• W2065691470 countsByYear W20656914702014 @default.
• W2065691470 countsByYear W20656914702015 @default.
• W2065691470 countsByYear W20656914702016 @default.
• W2065691470 countsByYear W20656914702017 @default.
• W2065691470 countsByYear W20656914702018 @default.
• W2065691470 countsByYear W20656914702019 @default.
• W2065691470 countsByYear W20656914702020 @default.
• W2065691470 countsByYear W20656914702021 @default.
• W2065691470 countsByYear W20656914702022 @default.
• W2065691470 countsByYear W20656914702023 @default.
• W2065691470 crossrefType "journal-article" @default.
• W2065691470 hasAuthorship W2065691470A5033485888 @default.
• W2065691470 hasAuthorship W2065691470A5056468131 @default.
• W2065691470 hasAuthorship W2065691470A5062403608 @default.
• W2065691470 hasAuthorship W2065691470A5075738977 @default.
• W2065691470 hasAuthorship W2065691470A5079505297 @default.
• W2065691470 hasAuthorship W2065691470A5082099245 @default.
• W2065691470 hasConcept C120089663 @default.
• W2065691470 hasConcept C124320809 @default.
• W2065691470 hasConcept C1491633281 @default.

• next