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• W2065718044 abstract "Thalidomide, (1), is a known inhibitor of TNF-alpha release in LPS stimulated human PBMC. Herein we describe the TNF-alpha inhibitory activity of amino substituted analogs of thalidomide (1) and its isoindolin-1-one analog, EM-12 (2). The 4-amino substituted analogs were found to be potent inhibitors of TNF-alpha release in LPS stimulated human PBMC." @default.
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• W2065718044 date "1999-06-01" @default.
• W2065718044 modified "2023-10-17" @default.
• W2065718044 title "Amino-substituted thalidomide analogs: Potent inhibitors of TNF-α production" @default.
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• W2065718044 doi "https://doi.org/10.1016/s0960-894x(99)00250-4" @default.
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