FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2065761290> ?p ?o ?g. }

• W2065761290 endingPage "368" @default.
• W2065761290 startingPage "361" @default.
• W2065761290 abstract "Vives A, Balasch J, Yagüe J, Quintó L, Ordi J, Vanrell JA. Type-1 and type-2 cytokines in human decidual tissue and trophoblasts from normal and abnormal pregnancies detected by reverse transcriptase polymerase chain reaction (RT-PCR). AJRI 1999; 42:361–368 © Munksgaard, Copenhagen PROBLEM: Cytokine expression at the maternal–fetal interface has been well documented in rodents, but data in the human are scanty and controversial. METHOD OF STUDY: We examined cytokine expression of human decidua and trophoblasts by semiquantitative visual grading of reverse transcriptase polymerase chain reaction (RT-PCR) products in five groups of patients: ten patients with uncomplicated term pregnancies undergoing elective cesarean section (Group 1); ten women having normal pregnancies at term and vaginal delivery (Group 2); ten patients having intrauterine growth-retarded infants of unknown cause after a spontaneous vaginal delivery at term (Group 3); ten childless women having their first, first-trimester spontaneous abortion (Group 4); and ten childless women with a history of one or more previous first-trimester spontaneous abortions and having a new miscarriage (Group 5). RESULTS: Results favoring the T-helper 1 (Th1)/T-helper 2 (Th2) model during pregnancy were: significantly higher expression of interferon gamma (IFN-γ) in trophoblast samples from Group 3 versus 2 and in decidual tissue from Group 5 versus 4; stronger positivity of interleukin (IL)-10 in decidual tissue samples from Group 1 versus Groups 2 and 5; and higher expression levels of tumor necrosis factor-β (TNF)-β by the trophoblast in Group 5 versus 1. Against the Th1/Th2 paradigm were the following findings: the significantly increased expression of IFN-γ by decidual or trophoblast samples in Groups 1 versus 2, 2 versus 3, and 1 versus 5; and the significantly higher expression of TNF-α in decidual samples from patients in Group 1 (but also Group 4) as compared with Group 5. IL-2 mRNA and IL-4 mRNA could not be detected. CONCLUSIONS: Overall, our findings suggest that there is a balance between type-1 and type-2 cytokines during pregnancy, which is mainly characterized by the expression of IFN-γ (a type-1 cytokine) and IL-10 (a type-2 cytokine) at the maternal–fetal interface." @default.
• W2065761290 created "2016-06-24" @default.
• W2065761290 creator A5008724866 @default.
• W2065761290 creator A5014460676 @default.
• W2065761290 creator A5037913108 @default.
• W2065761290 creator A5049987278 @default.
• W2065761290 creator A5082488254 @default.
• W2065761290 creator A5086821007 @default.
• W2065761290 date "1999-12-01" @default.
• W2065761290 modified "2023-10-16" @default.
• W2065761290 title "Type-1 and Type-2 Cytokines in Human Decidual Tissue and Trophoblasts from Normal and Abnormal Pregnancies Detected by Reverse Transcriptase Polymerase Chain Reaction (RT-PCR)" @default.
• W2065761290 cites W1546288178 @default.
• W2065761290 cites W1972922050 @default.
• W2065761290 cites W1975810161 @default.
• W2065761290 cites W1983895762 @default.
• W2065761290 cites W2005992769 @default.
• W2065761290 cites W2009618893 @default.
• W2065761290 cites W2019239536 @default.
• W2065761290 cites W2041001602 @default.
• W2065761290 cites W2060333964 @default.
• W2065761290 cites W2060334687 @default.
• W2065761290 cites W2087717265 @default.
• W2065761290 cites W2088103863 @default.
• W2065761290 cites W2092885675 @default.
• W2065761290 cites W2094147891 @default.
• W2065761290 cites W2094498402 @default.
• W2065761290 cites W2095491663 @default.
• W2065761290 cites W2103901688 @default.
• W2065761290 cites W2117348443 @default.
• W2065761290 cites W2130230171 @default.
• W2065761290 cites W2158500407 @default.
• W2065761290 cites W2319556727 @default.
• W2065761290 cites W2341216489 @default.
• W2065761290 cites W4239330593 @default.
• W2065761290 cites W4255861305 @default.
• W2065761290 doi "https://doi.org/10.1111/j.1600-0897.1999.tb00113.x" @default.
• W2065761290 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10622466" @default.
• W2065761290 hasPublicationYear "1999" @default.
• W2065761290 type Work @default.
• W2065761290 sameAs 2065761290 @default.
• W2065761290 citedByCount "47" @default.
• W2065761290 countsByYear W20657612902012 @default.
• W2065761290 countsByYear W20657612902013 @default.
• W2065761290 countsByYear W20657612902014 @default.
• W2065761290 countsByYear W20657612902015 @default.
• W2065761290 countsByYear W20657612902019 @default.
• W2065761290 countsByYear W20657612902020 @default.
• W2065761290 countsByYear W20657612902021 @default.
• W2065761290 countsByYear W20657612902022 @default.
• W2065761290 countsByYear W20657612902023 @default.
• W2065761290 crossrefType "journal-article" @default.
• W2065761290 hasAuthorship W2065761290A5008724866 @default.
• W2065761290 hasAuthorship W2065761290A5014460676 @default.
• W2065761290 hasAuthorship W2065761290A5037913108 @default.
• W2065761290 hasAuthorship W2065761290A5049987278 @default.
• W2065761290 hasAuthorship W2065761290A5082488254 @default.
• W2065761290 hasAuthorship W2065761290A5086821007 @default.
• W2065761290 hasConcept C104317684 @default.
• W2065761290 hasConcept C150194340 @default.
• W2065761290 hasConcept C156719811 @default.
• W2065761290 hasConcept C16685009 @default.
• W2065761290 hasConcept C172680121 @default.
• W2065761290 hasConcept C17991360 @default.
• W2065761290 hasConcept C203014093 @default.
• W2065761290 hasConcept C2776953305 @default.
• W2065761290 hasConcept C2777495146 @default.
• W2065761290 hasConcept C2778642596 @default.
• W2065761290 hasConcept C2778690821 @default.
• W2065761290 hasConcept C2779234561 @default.
• W2065761290 hasConcept C2779245376 @default.
• W2065761290 hasConcept C2780197806 @default.
• W2065761290 hasConcept C4692481 @default.
• W2065761290 hasConcept C48023723 @default.
• W2065761290 hasConcept C49105822 @default.
• W2065761290 hasConcept C54355233 @default.
• W2065761290 hasConcept C55493867 @default.
• W2065761290 hasConcept C71924100 @default.
• W2065761290 hasConcept C86803240 @default.
• W2065761290 hasConceptScore W2065761290C104317684 @default.
• W2065761290 hasConceptScore W2065761290C150194340 @default.
• W2065761290 hasConceptScore W2065761290C156719811 @default.
• W2065761290 hasConceptScore W2065761290C16685009 @default.
• W2065761290 hasConceptScore W2065761290C172680121 @default.
• W2065761290 hasConceptScore W2065761290C17991360 @default.
• W2065761290 hasConceptScore W2065761290C203014093 @default.
• W2065761290 hasConceptScore W2065761290C2776953305 @default.
• W2065761290 hasConceptScore W2065761290C2777495146 @default.
• W2065761290 hasConceptScore W2065761290C2778642596 @default.
• W2065761290 hasConceptScore W2065761290C2778690821 @default.
• W2065761290 hasConceptScore W2065761290C2779234561 @default.
• W2065761290 hasConceptScore W2065761290C2779245376 @default.
• W2065761290 hasConceptScore W2065761290C2780197806 @default.
• W2065761290 hasConceptScore W2065761290C4692481 @default.
• W2065761290 hasConceptScore W2065761290C48023723 @default.
• W2065761290 hasConceptScore W2065761290C49105822 @default.
• W2065761290 hasConceptScore W2065761290C54355233 @default.
• W2065761290 hasConceptScore W2065761290C55493867 @default.
• W2065761290 hasConceptScore W2065761290C71924100 @default.

• next