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- W206577029 abstract "Since 1980, --65 patients with hemispheric malignant gliomas have been treated in studies testing Cf-252 neutron brain implant therapy combined with whole/part brain radiotherapy to --6000 cGy. Methods, techniques, number of tubes implanted and the placement of tubes relative to the contrast enhanced edge of the tumor and brain imaging have evolved during this time. The patients receiving single tube implant had marked improvement in their performance status but a survival period of only --1 year. With the use of multiple tubes, survival results improved and was 63% at 12 months and continues at --30% at about 2 years. The advent of tumor staging using CT and MR scanning, multiple tube stereotaxic implants placed around the enhancing edge of the lesion and whole/part brain radiation may further improve local tumor control. Methods for the conduct of a therapeutic trial that could lead to more effective treatment of malignant tumors appear to be evolving." @default.
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- W206577029 date "1986-01-01" @default.
- W206577029 modified "2023-09-24" @default.
- W206577029 title "Cf-252 brain implantation for malignant glioma: Experience of the University of Kentucky, Lexington" @default.
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