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- W2065800110 abstract "To analyze the effect of a prevention program on the estimated cardiovascular risk calculated by three risk scores.We prospectively evaluated 87 HIV + patients with elevated cardiovascular risk estimation. Framingham (FRS), PROCAM and National Cholesterol Education Program (ATP-III) were applied. Cardiovascular risk was defined as elevated if >10%. All patients received non-pharmacological (diet, exercise, smoking cessation) and, when appropriate, pharmacological therapy.Mean age was 52 years, 92% were male, 39.1% were smokers, 70.1% had hypertension, 18.4% had diabetes. All patients were under HAART, 56.3% were receiving protease inhibitors (PI). After 6 months, intervention was associated to significant changes on triglycerides (298 ± 242 and 206 ± 135 mg/dL, p < 0.05), total-cholesterol (224 ± 47 and 189 ± 38 mg/dL, p < 0.001), LDL-cholesterol (129 ± 44 and 109 ± 30 mg/dL, p < 0.001). Frequencies of patients with elevated cardiac risk before and 6 months after intervention were 92% × 27.6% (p < 0.0001), 80.5% × 50.6% (p < 0.0002), and 25.3% × 14.9% (p = 0.12), for FRS, ATP III and PROCAM, respectively.An intervention program focused on reduction of traditional risk factors was able to decrease the frequency of patients with HIV infection and elevated cardiovascular risk estimation. FRS showed greater sensitivity than the other scores." @default.
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- W2065800110 date "2006-01-01" @default.
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- W2065800110 title "Mo-P5:317 The potential benefits of treating to LDL-C goal of 70 MG/DL vs 100 MG/DL in CHD/diabetic patients in Europe" @default.
- W2065800110 doi "https://doi.org/10.1016/s1567-5688(06)80450-2" @default.
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