FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2065808429> ?p ?o ?g. }

• W2065808429 endingPage "2071" @default.
• W2065808429 startingPage "2066" @default.
• W2065808429 abstract "Improving outcomes among class 3 thalassemia patients receiving allogeneic hematopoietic stem cell transplantations (HSCT) remains a challenge. Before HSCT, patients who were ≥ 7 years old and had a liver size ≥ 5 cm constitute what the Center for International Blood and Marrow Transplant Research defined as a very high-risk subset of a conventional high-risk class 3 group (here referred to as class 3 HR). We performed HSCT in 98 patients with related and unrelated donor stem cells. Seventy-six of the patients with age < 10 years received the more conventional myeloablative conditioning (MAC) regimen (cyclophosphamide, busulfan, ± fludarabine); the remaining 22 patients with age ≥ 10 years and hepatomegaly (class 3 HR), and in several instances additional comorbidity problems, underwent HSCT with a novel reduced-toxicity conditioning (RTC) regimen (fludarabine and busulfan). We then compared the outcomes between these 2 groups (MAC versus RTC). Event-free survival (86% versus 90%) and overall survival (95% versus 90%) were not significantly different between the respective groups; however, there was a higher incidence of serious treatment-related complications in the MAC group, and although we experienced 6 graft failures in the MAC group (8%), there were none in the RTC group. Based on these results, we suggest that (1) class 3 HR thalassemia patients can safely receive HSCT with our novel RTC regimen and achieve the same excellent outcome as low/standard-risk thalassemia patients who received the standard MAC regimen, and further, (2) that this novel RTC approach should be tested in the low/standard-risk patient population." @default.
• W2065808429 created "2016-06-24" @default.
• W2065808429 creator A5002213309 @default.
• W2065808429 creator A5003921591 @default.
• W2065808429 creator A5004417292 @default.
• W2065808429 creator A5008811956 @default.
• W2065808429 creator A5023506119 @default.
• W2065808429 creator A5027660444 @default.
• W2065808429 creator A5033742371 @default.
• W2065808429 creator A5035560719 @default.
• W2065808429 creator A5044686822 @default.
• W2065808429 creator A5049179921 @default.
• W2065808429 creator A5051418370 @default.
• W2065808429 creator A5057073485 @default.
• W2065808429 creator A5058068042 @default.
• W2065808429 creator A5060787586 @default.
• W2065808429 creator A5069953991 @default.
• W2065808429 creator A5074739571 @default.
• W2065808429 creator A5080964667 @default.
• W2065808429 date "2014-12-01" @default.
• W2065808429 modified "2023-10-16" @default.
• W2065808429 title "Outcomes of Thalassemia Patients Undergoing Hematopoietic Stem Cell Transplantation by Using a Standard Myeloablative versus a Novel Reduced-Toxicity Conditioning Regimen According to a New Risk Stratification" @default.
• W2065808429 cites W1599673581 @default.
• W2065808429 cites W1870629874 @default.
• W2065808429 cites W1978250290 @default.
• W2065808429 cites W2009019609 @default.
• W2065808429 cites W2018186485 @default.
• W2065808429 cites W2031205987 @default.
• W2065808429 cites W2031359173 @default.
• W2065808429 cites W2042888665 @default.
• W2065808429 cites W2070233046 @default.
• W2065808429 cites W2081132405 @default.
• W2065808429 cites W2097181590 @default.
• W2065808429 cites W2115105692 @default.
• W2065808429 cites W2118519447 @default.
• W2065808429 cites W2136016420 @default.
• W2065808429 cites W2272906907 @default.
• W2065808429 cites W2315168906 @default.
• W2065808429 doi "https://doi.org/10.1016/j.bbmt.2014.07.016" @default.
• W2065808429 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5538782" @default.
• W2065808429 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25064743" @default.
• W2065808429 hasPublicationYear "2014" @default.
• W2065808429 type Work @default.
• W2065808429 sameAs 2065808429 @default.
• W2065808429 citedByCount "38" @default.
• W2065808429 countsByYear W20658084292015 @default.
• W2065808429 countsByYear W20658084292016 @default.
• W2065808429 countsByYear W20658084292017 @default.
• W2065808429 countsByYear W20658084292018 @default.
• W2065808429 countsByYear W20658084292019 @default.
• W2065808429 countsByYear W20658084292020 @default.
• W2065808429 countsByYear W20658084292021 @default.
• W2065808429 countsByYear W20658084292022 @default.
• W2065808429 countsByYear W20658084292023 @default.
• W2065808429 crossrefType "journal-article" @default.
• W2065808429 hasAuthorship W2065808429A5002213309 @default.
• W2065808429 hasAuthorship W2065808429A5003921591 @default.
• W2065808429 hasAuthorship W2065808429A5004417292 @default.
• W2065808429 hasAuthorship W2065808429A5008811956 @default.
• W2065808429 hasAuthorship W2065808429A5023506119 @default.
• W2065808429 hasAuthorship W2065808429A5027660444 @default.
• W2065808429 hasAuthorship W2065808429A5033742371 @default.
• W2065808429 hasAuthorship W2065808429A5035560719 @default.
• W2065808429 hasAuthorship W2065808429A5044686822 @default.
• W2065808429 hasAuthorship W2065808429A5049179921 @default.
• W2065808429 hasAuthorship W2065808429A5051418370 @default.
• W2065808429 hasAuthorship W2065808429A5057073485 @default.
• W2065808429 hasAuthorship W2065808429A5058068042 @default.
• W2065808429 hasAuthorship W2065808429A5060787586 @default.
• W2065808429 hasAuthorship W2065808429A5069953991 @default.
• W2065808429 hasAuthorship W2065808429A5074739571 @default.
• W2065808429 hasAuthorship W2065808429A5080964667 @default.
• W2065808429 hasBestOaLocation W20658084291 @default.
• W2065808429 hasConcept C126322002 @default.
• W2065808429 hasConcept C141071460 @default.
• W2065808429 hasConcept C2776694085 @default.
• W2065808429 hasConcept C2776755627 @default.
• W2065808429 hasConcept C2777408962 @default.
• W2065808429 hasConcept C2777799968 @default.
• W2065808429 hasConcept C2779263901 @default.
• W2065808429 hasConcept C2780611847 @default.
• W2065808429 hasConcept C2781413609 @default.
• W2065808429 hasConcept C2911091166 @default.
• W2065808429 hasConcept C71924100 @default.
• W2065808429 hasConceptScore W2065808429C126322002 @default.
• W2065808429 hasConceptScore W2065808429C141071460 @default.
• W2065808429 hasConceptScore W2065808429C2776694085 @default.
• W2065808429 hasConceptScore W2065808429C2776755627 @default.
• W2065808429 hasConceptScore W2065808429C2777408962 @default.
• W2065808429 hasConceptScore W2065808429C2777799968 @default.
• W2065808429 hasConceptScore W2065808429C2779263901 @default.
• W2065808429 hasConceptScore W2065808429C2780611847 @default.
• W2065808429 hasConceptScore W2065808429C2781413609 @default.
• W2065808429 hasConceptScore W2065808429C2911091166 @default.
• W2065808429 hasConceptScore W2065808429C71924100 @default.
• W2065808429 hasFunder F4320307057 @default.
• W2065808429 hasFunder F4320322401 @default.
• W2065808429 hasFunder F4320322437 @default.

• next