Matches in SemOpenAlex for { <https://semopenalex.org/work/W2065839340> ?p ?o ?g. }
Showing items 1 to 62 of
62
with 100 items per page.
- W2065839340 abstract "OBJECTIVETo evaluate the use of fibrin glue as a scaffold for patching defects in the tunica albuginea in a rabbit model for a future application in correcting chordee.MATERIALS AND METHODSNine New Zealand white male rabbits were utilized. All had a 15 × 5-mm defect created in the ventral tunica albuginea. Fibrin glue (1 mL) was applied to cover the defect in tunica albuginea and the penile skin closed with a continuous 5/0 chromic catgut suture. Animals were killed in groups of three at 2, 6 and 12 weeks afterward. The evaluation included an artificial erection test with intracavernosal injection of prostaglandin E1 (5 µg), cavernosography and histopathological examination of sections of the penis stained with haematoxylin and eosin or Masson trichrome.RESULTSNone of the rabbits died during the procedure or developed bleeding or haematoma afterward. All animals had straight erections on testing with prostaglandin (5 µg). There was no evidence of corporal narrowing or venous leakage on cavernosography. Histopathological evaluation showed evidence of the fibrin sealant layer, with angiogenesis and a cell infiltrate at 2 weeks. At 6 and 12 weeks there was completely normal regeneration of the tunica albuginea.CONCLUSIONSIn this pilot study in a rabbit model the haemostatic effect of fibrin glue was confirmed on covering a defect in the tunica albuginea. Moreover, there was regeneration of normal tunica albuginea with no scarring at 6 weeks and maintained at 12 weeks. Further well-controlled studies are required before using fibrin glue for corporal body grafting to treat chordee." @default.
- W2065839340 created "2016-06-24" @default.
- W2065839340 creator A5008407807 @default.
- W2065839340 creator A5014521106 @default.
- W2065839340 creator A5088678612 @default.
- W2065839340 date "2006-03-01" @default.
- W2065839340 modified "2023-09-25" @default.
- W2065839340 title "Fibrin Glue for the Suture-Less Correction of Penile Chordee: A Pilot Study in a Rabbit Model" @default.
- W2065839340 doi "https://doi.org/10.1016/s0022-5347(05)00618-x" @default.
- W2065839340 hasPublicationYear "2006" @default.
- W2065839340 type Work @default.
- W2065839340 sameAs 2065839340 @default.
- W2065839340 citedByCount "0" @default.
- W2065839340 crossrefType "journal-article" @default.
- W2065839340 hasAuthorship W2065839340A5008407807 @default.
- W2065839340 hasAuthorship W2065839340A5014521106 @default.
- W2065839340 hasAuthorship W2065839340A5088678612 @default.
- W2065839340 hasConcept C105702510 @default.
- W2065839340 hasConcept C141071460 @default.
- W2065839340 hasConcept C142724271 @default.
- W2065839340 hasConcept C163031210 @default.
- W2065839340 hasConcept C203014093 @default.
- W2065839340 hasConcept C2777327002 @default.
- W2065839340 hasConcept C2777786686 @default.
- W2065839340 hasConcept C2778803959 @default.
- W2065839340 hasConcept C2780035233 @default.
- W2065839340 hasConcept C2780350170 @default.
- W2065839340 hasConcept C2781472170 @default.
- W2065839340 hasConcept C54173615 @default.
- W2065839340 hasConcept C71924100 @default.
- W2065839340 hasConcept C74864618 @default.
- W2065839340 hasConceptScore W2065839340C105702510 @default.
- W2065839340 hasConceptScore W2065839340C141071460 @default.
- W2065839340 hasConceptScore W2065839340C142724271 @default.
- W2065839340 hasConceptScore W2065839340C163031210 @default.
- W2065839340 hasConceptScore W2065839340C203014093 @default.
- W2065839340 hasConceptScore W2065839340C2777327002 @default.
- W2065839340 hasConceptScore W2065839340C2777786686 @default.
- W2065839340 hasConceptScore W2065839340C2778803959 @default.
- W2065839340 hasConceptScore W2065839340C2780035233 @default.
- W2065839340 hasConceptScore W2065839340C2780350170 @default.
- W2065839340 hasConceptScore W2065839340C2781472170 @default.
- W2065839340 hasConceptScore W2065839340C54173615 @default.
- W2065839340 hasConceptScore W2065839340C71924100 @default.
- W2065839340 hasConceptScore W2065839340C74864618 @default.
- W2065839340 hasLocation W20658393401 @default.
- W2065839340 hasOpenAccess W2065839340 @default.
- W2065839340 hasPrimaryLocation W20658393401 @default.
- W2065839340 hasRelatedWork W1975800916 @default.
- W2065839340 hasRelatedWork W2043959024 @default.
- W2065839340 hasRelatedWork W2078850306 @default.
- W2065839340 hasRelatedWork W2127481870 @default.
- W2065839340 hasRelatedWork W2130599579 @default.
- W2065839340 hasRelatedWork W2392647242 @default.
- W2065839340 hasRelatedWork W2783308203 @default.
- W2065839340 hasRelatedWork W2965429542 @default.
- W2065839340 hasRelatedWork W3139083191 @default.
- W2065839340 hasRelatedWork W3175227598 @default.
- W2065839340 isParatext "false" @default.
- W2065839340 isRetracted "false" @default.
- W2065839340 magId "2065839340" @default.
- W2065839340 workType "article" @default.