Matches in SemOpenAlex for { <https://semopenalex.org/work/W2065846922> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2065846922 abstract "The chronotropic effect of three beta-1-adrenoceptor partial agonists prenalterol, xamoterol and epanolol has been compared on the right atria of the rat in order to evaluate their intrinsic activity and to place them in rank order of effectiveness. The results show that prenalterol, xamoterol and epanolol are all partial agonists. The intrinsic activities relative to that of isoprenaline are 0.84 for prenalterol, 0.59 for xamoterol and 0.29 for epanolol. This rank order of intrinsic activities should remain the same in different species and in man. Both atenolol and propranolol reversed the chronotropic effects of the three agonists. The KB of the two blockers was similar against prenalterol and xamoterol, which indicates that the two partial agonists are probably competing for the same population of receptors. The EC50 is twice as large than KB for xamoterol, which is consistent with isoprenaline working through both beta-1- and beta-2- receptors and xamoterol finds it more difficult to block the beta-2-receptors." @default.
- W2065846922 created "2016-06-24" @default.
- W2065846922 creator A5069782407 @default.
- W2065846922 creator A5069977890 @default.
- W2065846922 creator A5085026389 @default.
- W2065846922 creator A5087410088 @default.
- W2065846922 date "1991-11-01" @default.
- W2065846922 modified "2023-09-26" @default.
- W2065846922 title "Comparative Effects of β-Adrenoceptor Partial Agonists on" @default.
- W2065846922 cites W1964444250 @default.
- W2065846922 cites W1980291715 @default.
- W2065846922 cites W1989867899 @default.
- W2065846922 cites W1995142144 @default.
- W2065846922 cites W2024456734 @default.
- W2065846922 cites W2028326172 @default.
- W2065846922 cites W2029245433 @default.
- W2065846922 cites W2047025710 @default.
- W2065846922 cites W2049079652 @default.
- W2065846922 cites W2143605028 @default.
- W2065846922 cites W4211208767 @default.
- W2065846922 doi "https://doi.org/10.1111/j.1600-0773.1991.tb01309.x" @default.
- W2065846922 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1687080" @default.
- W2065846922 hasPublicationYear "1991" @default.
- W2065846922 type Work @default.
- W2065846922 sameAs 2065846922 @default.
- W2065846922 citedByCount "0" @default.
- W2065846922 crossrefType "journal-article" @default.
- W2065846922 hasAuthorship W2065846922A5069782407 @default.
- W2065846922 hasAuthorship W2065846922A5069977890 @default.
- W2065846922 hasAuthorship W2065846922A5085026389 @default.
- W2065846922 hasAuthorship W2065846922A5087410088 @default.
- W2065846922 hasConcept C126322002 @default.
- W2065846922 hasConcept C158328960 @default.
- W2065846922 hasConcept C170493617 @default.
- W2065846922 hasConcept C185592680 @default.
- W2065846922 hasConcept C199360897 @default.
- W2065846922 hasConcept C24998067 @default.
- W2065846922 hasConcept C2776090920 @default.
- W2065846922 hasConcept C2776174256 @default.
- W2065846922 hasConcept C2776525901 @default.
- W2065846922 hasConcept C2777953023 @default.
- W2065846922 hasConcept C2778151854 @default.
- W2065846922 hasConcept C2778938600 @default.
- W2065846922 hasConcept C2908647359 @default.
- W2065846922 hasConcept C38533456 @default.
- W2065846922 hasConcept C41008148 @default.
- W2065846922 hasConcept C58732023 @default.
- W2065846922 hasConcept C71924100 @default.
- W2065846922 hasConcept C84393581 @default.
- W2065846922 hasConcept C98274493 @default.
- W2065846922 hasConcept C99454951 @default.
- W2065846922 hasConceptScore W2065846922C126322002 @default.
- W2065846922 hasConceptScore W2065846922C158328960 @default.
- W2065846922 hasConceptScore W2065846922C170493617 @default.
- W2065846922 hasConceptScore W2065846922C185592680 @default.
- W2065846922 hasConceptScore W2065846922C199360897 @default.
- W2065846922 hasConceptScore W2065846922C24998067 @default.
- W2065846922 hasConceptScore W2065846922C2776090920 @default.
- W2065846922 hasConceptScore W2065846922C2776174256 @default.
- W2065846922 hasConceptScore W2065846922C2776525901 @default.
- W2065846922 hasConceptScore W2065846922C2777953023 @default.
- W2065846922 hasConceptScore W2065846922C2778151854 @default.
- W2065846922 hasConceptScore W2065846922C2778938600 @default.
- W2065846922 hasConceptScore W2065846922C2908647359 @default.
- W2065846922 hasConceptScore W2065846922C38533456 @default.
- W2065846922 hasConceptScore W2065846922C41008148 @default.
- W2065846922 hasConceptScore W2065846922C58732023 @default.
- W2065846922 hasConceptScore W2065846922C71924100 @default.
- W2065846922 hasConceptScore W2065846922C84393581 @default.
- W2065846922 hasConceptScore W2065846922C98274493 @default.
- W2065846922 hasConceptScore W2065846922C99454951 @default.
- W2065846922 hasLocation W20658469221 @default.
- W2065846922 hasLocation W20658469222 @default.
- W2065846922 hasOpenAccess W2065846922 @default.
- W2065846922 hasPrimaryLocation W20658469221 @default.
- W2065846922 hasRelatedWork W1981676817 @default.
- W2065846922 hasRelatedWork W1996069427 @default.
- W2065846922 hasRelatedWork W2007101572 @default.
- W2065846922 hasRelatedWork W2025691732 @default.
- W2065846922 hasRelatedWork W2045341648 @default.
- W2065846922 hasRelatedWork W2065846922 @default.
- W2065846922 hasRelatedWork W2089058217 @default.
- W2065846922 hasRelatedWork W2155904913 @default.
- W2065846922 hasRelatedWork W2409909350 @default.
- W2065846922 hasRelatedWork W2461011061 @default.
- W2065846922 isParatext "false" @default.
- W2065846922 isRetracted "false" @default.
- W2065846922 magId "2065846922" @default.
- W2065846922 workType "article" @default.