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- W2065860156 abstract "To the Editor.— The article of F. A. Herrero on lithium carbonate toxicity (226:1109, 1973) deserves comment. Some authorities believe lithium carbonate is one of the most underused neuroleptic drugs. Though considered safe within the appropriate therapeutic range (0.6 to 1.2 mEq/liter), it is always important to know about idiosyncrasies, so that physicians may take appropriate measures. Awareness of these unusual cases, however, should be created without stimulating exaggerated fears that may inhibit use in cases where lithium is clearly indicated. Both the report and the editorial note fail to recognize recent findings suggesting that appropriate treatment for acute manic episodes should include phenothiazines or butyrophenones. This treatment method is more effective in controlling the initial symptoms of hyperactivity during the waiting period of seven to ten days necessary for lithium activity. It also decreases the need for blood lithium levels as high as 1.5 mEq/liter, thus lowering the risk" @default.
- W2065860156 created "2016-06-24" @default.
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- W2065860156 date "1974-02-25" @default.
- W2065860156 modified "2023-09-27" @default.
- W2065860156 title "Lithium Carbonate Toxicity" @default.
- W2065860156 cites W2029738937 @default.
- W2065860156 doi "https://doi.org/10.1001/jama.1974.03230210051023" @default.
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