Matches in SemOpenAlex for { <https://semopenalex.org/work/W2065903553> ?p ?o ?g. }
- W2065903553 endingPage "456" @default.
- W2065903553 startingPage "453" @default.
- W2065903553 abstract "Background Subthalamic Nucleus Deep Brain Stimulation (STN-DBS) represents a valid therapeutic option for advanced Parkinson's disease (PD), leading to a significant amelioration of motor fluctuations and levodopa-induced involuntary movements (IM). This study address the issue of whether stimulation frequency may influence the control of IM in STN-DBS treated patients, comparing the effects of 80 Hz and 130 Hz STN-DBS frequencies in 10 parkinsonian patients with residual IM (dyskinesia in 6 cases and dystonia in 4 cases). Methods Patients were evaluated by means of the Rush Dyskinesias Rating Scale (blinded-video analysis) and Unified Parkinson's Disease Rating Scale at 4 different time-points: baseline, shortly after the switch of stimulation frequency from 130 Hz to 80 Hz, after 1 month and 12 months of chronic 80 Hz stimulation. Results IM improved in most subjects after the switch of stimulation frequency: dyskinesias improved in 6/6 subjects and dystonic features in 3/4 subjects after one month of 80 Hz stimulation. However, the 130 Hz STN stimulation was restored in 4 subjects during the following months, because of a gradual worsening of parkinsonian symptoms. A sustained efficacy on motor features and IM was observed with 80 Hz stimulation frequency in the remaining patients. Conclusions In this limited cohort of STN-DBS patients, we observed an improvement of residual IM after the switch of stimulation frequency from 130 Hz to 80 Hz. However, a moderate worsening of parkinsonian symptoms was observed in a portion of patients, requiring to return at 130 Hz STN-DBS." @default.
- W2065903553 created "2016-06-24" @default.
- W2065903553 creator A5006934160 @default.
- W2065903553 creator A5014834553 @default.
- W2065903553 creator A5026656633 @default.
- W2065903553 creator A5052765423 @default.
- W2065903553 creator A5060573388 @default.
- W2065903553 creator A5063103477 @default.
- W2065903553 creator A5074538393 @default.
- W2065903553 creator A5081285710 @default.
- W2065903553 date "2013-04-01" @default.
- W2065903553 modified "2023-10-17" @default.
- W2065903553 title "80 Hz versus 130 Hz subthalamic nucleus deep brain stimulation: Effects on involuntary movements" @default.
- W2065903553 cites W1982523729 @default.
- W2065903553 cites W2000747321 @default.
- W2065903553 cites W2010206976 @default.
- W2065903553 cites W2029940240 @default.
- W2065903553 cites W2042326165 @default.
- W2065903553 cites W2052510409 @default.
- W2065903553 cites W2062278196 @default.
- W2065903553 cites W2139516600 @default.
- W2065903553 cites W2140001342 @default.
- W2065903553 cites W2151976530 @default.
- W2065903553 cites W2152069319 @default.
- W2065903553 cites W4236117762 @default.
- W2065903553 doi "https://doi.org/10.1016/j.parkreldis.2013.01.006" @default.
- W2065903553 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23395217" @default.
- W2065903553 hasPublicationYear "2013" @default.
- W2065903553 type Work @default.
- W2065903553 sameAs 2065903553 @default.
- W2065903553 citedByCount "21" @default.
- W2065903553 countsByYear W20659035532014 @default.
- W2065903553 countsByYear W20659035532015 @default.
- W2065903553 countsByYear W20659035532016 @default.
- W2065903553 countsByYear W20659035532018 @default.
- W2065903553 countsByYear W20659035532019 @default.
- W2065903553 countsByYear W20659035532021 @default.
- W2065903553 countsByYear W20659035532022 @default.
- W2065903553 countsByYear W20659035532023 @default.
- W2065903553 crossrefType "journal-article" @default.
- W2065903553 hasAuthorship W2065903553A5006934160 @default.
- W2065903553 hasAuthorship W2065903553A5014834553 @default.
- W2065903553 hasAuthorship W2065903553A5026656633 @default.
- W2065903553 hasAuthorship W2065903553A5052765423 @default.
- W2065903553 hasAuthorship W2065903553A5060573388 @default.
- W2065903553 hasAuthorship W2065903553A5063103477 @default.
- W2065903553 hasAuthorship W2065903553A5074538393 @default.
- W2065903553 hasAuthorship W2065903553A5081285710 @default.
- W2065903553 hasBestOaLocation W20659035532 @default.
- W2065903553 hasConcept C126322002 @default.
- W2065903553 hasConcept C138496976 @default.
- W2065903553 hasConcept C15744967 @default.
- W2065903553 hasConcept C169760540 @default.
- W2065903553 hasConcept C24998067 @default.
- W2065903553 hasConcept C2777319143 @default.
- W2065903553 hasConcept C2778261627 @default.
- W2065903553 hasConcept C2778542668 @default.
- W2065903553 hasConcept C2778559928 @default.
- W2065903553 hasConcept C2779134260 @default.
- W2065903553 hasConcept C2779734285 @default.
- W2065903553 hasConcept C2780304432 @default.
- W2065903553 hasConcept C2780405171 @default.
- W2065903553 hasConcept C3018987647 @default.
- W2065903553 hasConcept C42219234 @default.
- W2065903553 hasConcept C548259974 @default.
- W2065903553 hasConcept C71924100 @default.
- W2065903553 hasConcept C83849319 @default.
- W2065903553 hasConcept C99508421 @default.
- W2065903553 hasConceptScore W2065903553C126322002 @default.
- W2065903553 hasConceptScore W2065903553C138496976 @default.
- W2065903553 hasConceptScore W2065903553C15744967 @default.
- W2065903553 hasConceptScore W2065903553C169760540 @default.
- W2065903553 hasConceptScore W2065903553C24998067 @default.
- W2065903553 hasConceptScore W2065903553C2777319143 @default.
- W2065903553 hasConceptScore W2065903553C2778261627 @default.
- W2065903553 hasConceptScore W2065903553C2778542668 @default.
- W2065903553 hasConceptScore W2065903553C2778559928 @default.
- W2065903553 hasConceptScore W2065903553C2779134260 @default.
- W2065903553 hasConceptScore W2065903553C2779734285 @default.
- W2065903553 hasConceptScore W2065903553C2780304432 @default.
- W2065903553 hasConceptScore W2065903553C2780405171 @default.
- W2065903553 hasConceptScore W2065903553C3018987647 @default.
- W2065903553 hasConceptScore W2065903553C42219234 @default.
- W2065903553 hasConceptScore W2065903553C548259974 @default.
- W2065903553 hasConceptScore W2065903553C71924100 @default.
- W2065903553 hasConceptScore W2065903553C83849319 @default.
- W2065903553 hasConceptScore W2065903553C99508421 @default.
- W2065903553 hasIssue "4" @default.
- W2065903553 hasLocation W20659035531 @default.
- W2065903553 hasLocation W20659035532 @default.
- W2065903553 hasLocation W20659035533 @default.
- W2065903553 hasOpenAccess W2065903553 @default.
- W2065903553 hasPrimaryLocation W20659035531 @default.
- W2065903553 hasRelatedWork W2004140684 @default.
- W2065903553 hasRelatedWork W2107579380 @default.
- W2065903553 hasRelatedWork W2110669321 @default.
- W2065903553 hasRelatedWork W2115601613 @default.
- W2065903553 hasRelatedWork W2116470868 @default.