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- W2065905322 abstract "7 patients with primary humoral immunodeficiency were given an S-sulfonated IgG preparation, 100 mg/kg i.v. at intervals of 3--4 weeks, for treatment of, or prophylaxis against, infection. The clinical effects and metabolism of S-sulfonated IgG were studied. No side reactions attributable to S-sulfonated IgG occurred in any of the patients. The S-sulfonated IgG was completely transformed into intact IgG within 24 h after administration, and had a mean half-life of 21 days, comparable to that of intact IgG. Complete restoration of IgG Fc fragment activity occurred within 24 h following injection, as assessed by reversed passive cutaneous anaphylaxis." @default.
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- W2065905322 date "1979-07-01" @default.
- W2065905322 modified "2023-10-17" @default.
- W2065905322 title "Clinical Effect and Metabolism of S-Sulfonated Immunoglobulin in 7 Patients with Congenital Humoral Immunodeficiency" @default.
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- W2065905322 doi "https://doi.org/10.1111/j.1423-0410.1979.tb02263.x" @default.
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