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- W2065906084 abstract "Sickness behavior refers to the coordinated set of behavior changes that develop in sick individuals during the course of an infection. At the molecular level, these changes are due to the effects of proinflammatory cytokines as interleukin-1 on the brain. The purpose of this article is not to review the entire field of cytokines and behavior, but rather to address the role of interleukin-1 receptors (IL-1Rs) in sickness behavior. We briefly describe the notion of sickness behavior and present the distribution of IL-1Rs in the central nervous system of the human, mouse and rat. We then bring arguments in favor of the functionality of the various subtypes of receptors and evaluate the nature of the signaling pathways activated by brain IL-1Rs to initiate central modifications leading to symptoms of sickness. Finally, modulation of IL-1 action on its receptor by various opposing factors including glucocorticoids and anti-inflammatory cytokines is discussed." @default.
- W2065906084 created "2016-06-24" @default.
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- W2065906084 creator A5017757363 @default.
- W2065906084 creator A5078488552 @default.
- W2065906084 date "2002-04-01" @default.
- W2065906084 modified "2023-10-05" @default.
- W2065906084 title "Expression and regulation of interleukin-1 receptors in the brain. Role in cytokines-induced sickness behavior" @default.
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- W2065906084 cites W1571663010 @default.
- W2065906084 cites W1601899128 @default.
- W2065906084 cites W1763097477 @default.
- W2065906084 cites W1830583197 @default.
- W2065906084 cites W1836407144 @default.
- W2065906084 cites W1860299403 @default.
- W2065906084 cites W186555210 @default.
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- W2065906084 cites W189910528 @default.
- W2065906084 cites W1915518296 @default.
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- W2065906084 cites W2027015035 @default.
- W2065906084 cites W2032091078 @default.
- W2065906084 cites W2037280691 @default.
- W2065906084 cites W2040654348 @default.
- W2065906084 cites W2050032735 @default.
- W2065906084 cites W2050037580 @default.
- W2065906084 cites W2050235826 @default.
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- W2065906084 cites W2056397762 @default.
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- W2065906084 cites W2061903251 @default.
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- W2065906084 cites W2064676254 @default.
- W2065906084 cites W2066339186 @default.
- W2065906084 cites W2067383231 @default.
- W2065906084 cites W2078136106 @default.
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- W2065906084 cites W2188779778 @default.
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- W2065906084 cites W2257015281 @default.
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- W2065906084 doi "https://doi.org/10.1016/s0165-5728(02)00022-x" @default.
- W2065906084 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11960635" @default.
- W2065906084 hasPublicationYear "2002" @default.
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