FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2065926485> ?p ?o ?g. }

• W2065926485 endingPage "533" @default.
• W2065926485 startingPage "523" @default.
• W2065926485 abstract "We investigated whether simvastatin reduces lung injury caused by ischaemia–reperfusion of the hind limbs in rats. The control group underwent dissection of bilateral femoral arteries; another group (I/R group) underwent ischaemia of bilateral hind limbs for 2 h followed by 3 h reperfusion; and two other groups were pretreated with 5 or 10 mg/kg per day simvastatin for 3 days and then underwent ischaemia–reperfusion. The control and I/R group rats received placebo (water) instead of simvastatin. The lungs of the I/R rats showed marked histopathological changes compared with the other groups. Lung tissue myeloperoxidase, malondialdehyde, neutrophil count and lung injury scores in both simvastatin groups were significantly lower than in the I/R group; 10 mg/kg per day simvastatin significantly reduced lung water content although 5 mg/kg per day did not. Expression of haem oxygenase-1 (HO-1) protein in lung tissue was significantly greater in the simvastatin groups than in the I/R group. Simvastatin protects against lung injury associated with lower extremity ischaemia–reperfusion by reduction of neutrophil aggregation and oxidative damage, and upregulation of HO-1 expression in the injured lung." @default.
• W2065926485 created "2016-06-24" @default.
• W2065926485 creator A5012324685 @default.
• W2065926485 creator A5017312003 @default.
• W2065926485 creator A5029375859 @default.
• W2065926485 creator A5029508998 @default.
• W2065926485 creator A5031774992 @default.
• W2065926485 creator A5032097047 @default.
• W2065926485 creator A5074278130 @default.
• W2065926485 creator A5086706603 @default.
• W2065926485 date "2007-07-01" @default.
• W2065926485 modified "2023-09-26" @default.
• W2065926485 title "Effects of Simvastatin on Lung Injury Induced by Ischaemia–Reperfusion of the Hind Limbs in Rats" @default.
• W2065926485 cites W1538399032 @default.
• W2065926485 cites W1955146782 @default.
• W2065926485 cites W1965393811 @default.
• W2065926485 cites W1971917696 @default.
• W2065926485 cites W1975838930 @default.
• W2065926485 cites W1991320118 @default.
• W2065926485 cites W1992601930 @default.
• W2065926485 cites W2005385315 @default.
• W2065926485 cites W2008835687 @default.
• W2065926485 cites W2025887838 @default.
• W2065926485 cites W2031379379 @default.
• W2065926485 cites W2033827871 @default.
• W2065926485 cites W2033914311 @default.
• W2065926485 cites W2047614548 @default.
• W2065926485 cites W2054880820 @default.
• W2065926485 cites W2055655700 @default.
• W2065926485 cites W2062783674 @default.
• W2065926485 cites W2063649945 @default.
• W2065926485 cites W2065284764 @default.
• W2065926485 cites W2071124826 @default.
• W2065926485 cites W2075180364 @default.
• W2065926485 cites W2076110739 @default.
• W2065926485 cites W2085454145 @default.
• W2065926485 cites W2090555802 @default.
• W2065926485 cites W2093236229 @default.
• W2065926485 cites W2105977216 @default.
• W2065926485 cites W2111414235 @default.
• W2065926485 cites W2143626424 @default.
• W2065926485 cites W2160586011 @default.
• W2065926485 cites W2161117109 @default.
• W2065926485 cites W2398746403 @default.
• W2065926485 cites W4236038927 @default.
• W2065926485 doi "https://doi.org/10.1177/147323000703500412" @default.
• W2065926485 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17697530" @default.
• W2065926485 hasPublicationYear "2007" @default.
• W2065926485 type Work @default.
• W2065926485 sameAs 2065926485 @default.
• W2065926485 citedByCount "19" @default.
• W2065926485 countsByYear W20659264852012 @default.
• W2065926485 countsByYear W20659264852013 @default.
• W2065926485 countsByYear W20659264852016 @default.
• W2065926485 countsByYear W20659264852017 @default.
• W2065926485 countsByYear W20659264852018 @default.
• W2065926485 countsByYear W20659264852022 @default.
• W2065926485 crossrefType "journal-article" @default.
• W2065926485 hasAuthorship W2065926485A5012324685 @default.
• W2065926485 hasAuthorship W2065926485A5017312003 @default.
• W2065926485 hasAuthorship W2065926485A5029375859 @default.
• W2065926485 hasAuthorship W2065926485A5029508998 @default.
• W2065926485 hasAuthorship W2065926485A5031774992 @default.
• W2065926485 hasAuthorship W2065926485A5032097047 @default.
• W2065926485 hasAuthorship W2065926485A5074278130 @default.
• W2065926485 hasAuthorship W2065926485A5086706603 @default.
• W2065926485 hasBestOaLocation W20659264851 @default.
• W2065926485 hasConcept C126322002 @default.
• W2065926485 hasConcept C126894567 @default.
• W2065926485 hasConcept C134018914 @default.
• W2065926485 hasConcept C203565725 @default.
• W2065926485 hasConcept C2776151105 @default.
• W2065926485 hasConcept C2776329913 @default.
• W2065926485 hasConcept C2776914184 @default.
• W2065926485 hasConcept C2777714996 @default.
• W2065926485 hasConcept C2778401633 @default.
• W2065926485 hasConcept C2780114680 @default.
• W2065926485 hasConcept C42219234 @default.
• W2065926485 hasConcept C541997718 @default.
• W2065926485 hasConcept C71924100 @default.
• W2065926485 hasConceptScore W2065926485C126322002 @default.
• W2065926485 hasConceptScore W2065926485C126894567 @default.
• W2065926485 hasConceptScore W2065926485C134018914 @default.
• W2065926485 hasConceptScore W2065926485C203565725 @default.
• W2065926485 hasConceptScore W2065926485C2776151105 @default.
• W2065926485 hasConceptScore W2065926485C2776329913 @default.
• W2065926485 hasConceptScore W2065926485C2776914184 @default.
• W2065926485 hasConceptScore W2065926485C2777714996 @default.
• W2065926485 hasConceptScore W2065926485C2778401633 @default.
• W2065926485 hasConceptScore W2065926485C2780114680 @default.
• W2065926485 hasConceptScore W2065926485C42219234 @default.
• W2065926485 hasConceptScore W2065926485C541997718 @default.
• W2065926485 hasConceptScore W2065926485C71924100 @default.
• W2065926485 hasIssue "4" @default.
• W2065926485 hasLocation W20659264851 @default.
• W2065926485 hasLocation W20659264852 @default.
• W2065926485 hasOpenAccess W2065926485 @default.
• W2065926485 hasPrimaryLocation W20659264851 @default.

• next