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• W2065943612 abstract "Aurora kinases are key regulators of cell division and important targets for cancer therapy. We report that Binucleine 2 is a highly isoform-specific inhibitor of Drosophila Aurora B kinase, and we identify a single residue within the kinase active site that confers specificity for Aurora B. Using Binucleine 2, we show that Aurora B kinase activity is not required during contractile ring ingression, providing insight into the mechanism of cytokinesis." @default.
• W2065943612 created "2016-06-24" @default.
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• W2065943612 date "2010-08-30" @default.
• W2065943612 modified "2023-09-30" @default.
• W2065943612 title "Binucleine 2, an Isoform-Specific Inhibitor of <i>Drosophila</i> Aurora B Kinase, Provides Insights into the Mechanism of Cytokinesis" @default.
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• W2065943612 doi "https://doi.org/10.1021/cb1001685" @default.
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