Matches in SemOpenAlex for { <https://semopenalex.org/work/W2065953611> ?p ?o ?g. }
- W2065953611 endingPage "e57831" @default.
- W2065953611 startingPage "e57831" @default.
- W2065953611 abstract "Background Internet addiction has become increasingly recognized as a mental disorder, though its neurobiological basis is unknown. This study used functional neuroimaging to investigate whole-brain functional connectivity in adolescents diagnosed with internet addiction. Based on neurobiological changes seen in other addiction related disorders, it was predicted that connectivity disruptions in adolescents with internet addiction would be most prominent in cortico-striatal circuitry. Methods Participants were 12 adolescents diagnosed with internet addiction and 11 healthy comparison subjects. Resting-state functional magnetic resonance images were acquired, and group differences in brain functional connectivity were analyzed using the network-based statistic. We also analyzed network topology, testing for between-group differences in key graph-based network measures. Results Adolescents with internet addiction showed reduced functional connectivity spanning a distributed network. The majority of impaired connections involved cortico-subcortical circuits (∼24% with prefrontal and ∼27% with parietal cortex). Bilateral putamen was the most extensively involved subcortical brain region. No between-group difference was observed in network topological measures, including the clustering coefficient, characteristic path length, or the small-worldness ratio. Conclusions Internet addiction is associated with a widespread and significant decrease of functional connectivity in cortico-striatal circuits, in the absence of global changes in brain functional network topology." @default.
- W2065953611 created "2016-06-24" @default.
- W2065953611 creator A5010047680 @default.
- W2065953611 creator A5019492481 @default.
- W2065953611 creator A5029089458 @default.
- W2065953611 creator A5031170774 @default.
- W2065953611 creator A5037599926 @default.
- W2065953611 creator A5049063975 @default.
- W2065953611 creator A5059722141 @default.
- W2065953611 creator A5063216462 @default.
- W2065953611 creator A5076995446 @default.
- W2065953611 creator A5091503640 @default.
- W2065953611 date "2013-02-25" @default.
- W2065953611 modified "2023-10-02" @default.
- W2065953611 title "Decreased Functional Brain Connectivity in Adolescents with Internet Addiction" @default.
- W2065953611 cites W1511706046 @default.
- W2065953611 cites W1859758524 @default.
- W2065953611 cites W1965468519 @default.
- W2065953611 cites W1967931162 @default.
- W2065953611 cites W1970342641 @default.
- W2065953611 cites W1970695058 @default.
- W2065953611 cites W1976397511 @default.
- W2065953611 cites W1979777714 @default.
- W2065953611 cites W1983302342 @default.
- W2065953611 cites W1985267538 @default.
- W2065953611 cites W1985821218 @default.
- W2065953611 cites W1988157985 @default.
- W2065953611 cites W1990134753 @default.
- W2065953611 cites W1996630013 @default.
- W2065953611 cites W1999653836 @default.
- W2065953611 cites W2002117611 @default.
- W2065953611 cites W2002117922 @default.
- W2065953611 cites W2002923643 @default.
- W2065953611 cites W2007329502 @default.
- W2065953611 cites W2021986306 @default.
- W2065953611 cites W2029065091 @default.
- W2065953611 cites W2031292341 @default.
- W2065953611 cites W2033190760 @default.
- W2065953611 cites W2041190611 @default.
- W2065953611 cites W2041951497 @default.
- W2065953611 cites W2045758998 @default.
- W2065953611 cites W2047713573 @default.
- W2065953611 cites W2049732825 @default.
- W2065953611 cites W2055506938 @default.
- W2065953611 cites W2058046532 @default.
- W2065953611 cites W2060321692 @default.
- W2065953611 cites W2060397923 @default.
- W2065953611 cites W2061978884 @default.
- W2065953611 cites W2062571913 @default.
- W2065953611 cites W2064093160 @default.
- W2065953611 cites W2075038536 @default.
- W2065953611 cites W2076415515 @default.
- W2065953611 cites W2077817595 @default.
- W2065953611 cites W2078530990 @default.
- W2065953611 cites W2079163316 @default.
- W2065953611 cites W2086021750 @default.
- W2065953611 cites W2092655084 @default.
- W2065953611 cites W2093972428 @default.
- W2065953611 cites W2101790934 @default.
- W2065953611 cites W2102417060 @default.
- W2065953611 cites W2102436032 @default.
- W2065953611 cites W2115205784 @default.
- W2065953611 cites W2115687188 @default.
- W2065953611 cites W2116210000 @default.
- W2065953611 cites W2119618432 @default.
- W2065953611 cites W2120646564 @default.
- W2065953611 cites W2124141514 @default.
- W2065953611 cites W2124358336 @default.
- W2065953611 cites W2126838454 @default.
- W2065953611 cites W2127119730 @default.
- W2065953611 cites W2130419668 @default.
- W2065953611 cites W2131181615 @default.
- W2065953611 cites W2131892130 @default.
- W2065953611 cites W2132175842 @default.
- W2065953611 cites W2133750612 @default.
- W2065953611 cites W2135861595 @default.
- W2065953611 cites W2136395604 @default.
- W2065953611 cites W2138790588 @default.
- W2065953611 cites W2149495603 @default.
- W2065953611 cites W2156270499 @default.
- W2065953611 cites W2156372649 @default.
- W2065953611 cites W2156737316 @default.
- W2065953611 cites W2157685534 @default.
- W2065953611 cites W2158611196 @default.
- W2065953611 cites W2161198625 @default.
- W2065953611 cites W2163274894 @default.
- W2065953611 cites W2163479747 @default.
- W2065953611 cites W2165062525 @default.
- W2065953611 cites W2167822639 @default.
- W2065953611 cites W2169876268 @default.
- W2065953611 cites W2334742175 @default.
- W2065953611 cites W2341336124 @default.
- W2065953611 doi "https://doi.org/10.1371/journal.pone.0057831" @default.
- W2065953611 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3581468" @default.
- W2065953611 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23451272" @default.
- W2065953611 hasPublicationYear "2013" @default.
- W2065953611 type Work @default.
- W2065953611 sameAs 2065953611 @default.