Matches in SemOpenAlex for { <https://semopenalex.org/work/W2065955394> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2065955394 endingPage "1170" @default.
- W2065955394 startingPage "1165" @default.
- W2065955394 abstract "A 10 mg bolus of the angiotensin blocker saralasin was injected 113 times in 68 subjects with essential or renovascular hypertension. Ninety percent of injections caused a transient increase in blood pressure, which correlated with plasma renin activity (PRA) (r = -0.54); Mean increase at 2 minutes was 21/13.4 mm Hg (P less than 0.001) and was independent of pre-injection control blood pressure, with a rapid decrease to or below control values thereafter. Thirty-seven subjects were studied on successive days before and after furosemide-induced sodium depletion (152 +/- 26 mEq [SE] sodium loss). In the low renin group, sodium depletion did not change PRA or the magnitude of the pressor response to saralasin, but significantly decreased control MAP by 13 mm Hg (P less than 0.01). In normal and high renin patients, MAP was unchanged after diuresis, but PRA increased significantly and the pressor response was attenuated. The net effect of sodium depletion was to reduce the pressor response to saralasin in all renin subgroups by 9 to 12 mm Hg. Saralasin bolus injection, unlike infusion, saturates available vascular receptors only briefly, eliminating prolonged pressor responses." @default.
- W2065955394 created "2016-06-24" @default.
- W2065955394 creator A5013761386 @default.
- W2065955394 creator A5032098621 @default.
- W2065955394 creator A5053077642 @default.
- W2065955394 creator A5063187941 @default.
- W2065955394 creator A5077510368 @default.
- W2065955394 date "1978-06-01" @default.
- W2065955394 modified "2023-09-27" @default.
- W2065955394 title "Pressor response to saralasin (1-sar-8-ala-angiotensin II) bolus injection in hypertensive patients." @default.
- W2065955394 cites W1530906119 @default.
- W2065955394 cites W1972316794 @default.
- W2065955394 cites W1972646254 @default.
- W2065955394 cites W1975170163 @default.
- W2065955394 cites W1975622210 @default.
- W2065955394 cites W1993472933 @default.
- W2065955394 cites W2004095675 @default.
- W2065955394 cites W2005177038 @default.
- W2065955394 cites W2005386780 @default.
- W2065955394 cites W2008518019 @default.
- W2065955394 cites W2011010934 @default.
- W2065955394 cites W2012441754 @default.
- W2065955394 cites W2028748559 @default.
- W2065955394 cites W2028966975 @default.
- W2065955394 cites W2035352126 @default.
- W2065955394 cites W2041308262 @default.
- W2065955394 cites W2042420452 @default.
- W2065955394 cites W2058415311 @default.
- W2065955394 cites W2062426111 @default.
- W2065955394 cites W2087743295 @default.
- W2065955394 cites W2095125029 @default.
- W2065955394 cites W2096548736 @default.
- W2065955394 cites W2099920556 @default.
- W2065955394 cites W2144492790 @default.
- W2065955394 cites W2339423792 @default.
- W2065955394 cites W2394989193 @default.
- W2065955394 cites W2438420855 @default.
- W2065955394 cites W2905011142 @default.
- W2065955394 doi "https://doi.org/10.1161/01.cir.57.6.1165" @default.
- W2065955394 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/639240" @default.
- W2065955394 hasPublicationYear "1978" @default.
- W2065955394 type Work @default.
- W2065955394 sameAs 2065955394 @default.
- W2065955394 citedByCount "4" @default.
- W2065955394 crossrefType "journal-article" @default.
- W2065955394 hasAuthorship W2065955394A5013761386 @default.
- W2065955394 hasAuthorship W2065955394A5032098621 @default.
- W2065955394 hasAuthorship W2065955394A5053077642 @default.
- W2065955394 hasAuthorship W2065955394A5063187941 @default.
- W2065955394 hasAuthorship W2065955394A5077510368 @default.
- W2065955394 hasBestOaLocation W20659553941 @default.
- W2065955394 hasConcept C126322002 @default.
- W2065955394 hasConcept C134018914 @default.
- W2065955394 hasConcept C138976137 @default.
- W2065955394 hasConcept C159641895 @default.
- W2065955394 hasConcept C198710026 @default.
- W2065955394 hasConcept C2776823063 @default.
- W2065955394 hasConcept C2777955127 @default.
- W2065955394 hasConcept C2779547328 @default.
- W2065955394 hasConcept C2781243531 @default.
- W2065955394 hasConcept C2908929049 @default.
- W2065955394 hasConcept C43376680 @default.
- W2065955394 hasConcept C71924100 @default.
- W2065955394 hasConcept C84393581 @default.
- W2065955394 hasConceptScore W2065955394C126322002 @default.
- W2065955394 hasConceptScore W2065955394C134018914 @default.
- W2065955394 hasConceptScore W2065955394C138976137 @default.
- W2065955394 hasConceptScore W2065955394C159641895 @default.
- W2065955394 hasConceptScore W2065955394C198710026 @default.
- W2065955394 hasConceptScore W2065955394C2776823063 @default.
- W2065955394 hasConceptScore W2065955394C2777955127 @default.
- W2065955394 hasConceptScore W2065955394C2779547328 @default.
- W2065955394 hasConceptScore W2065955394C2781243531 @default.
- W2065955394 hasConceptScore W2065955394C2908929049 @default.
- W2065955394 hasConceptScore W2065955394C43376680 @default.
- W2065955394 hasConceptScore W2065955394C71924100 @default.
- W2065955394 hasConceptScore W2065955394C84393581 @default.
- W2065955394 hasIssue "6" @default.
- W2065955394 hasLocation W20659553941 @default.
- W2065955394 hasLocation W20659553942 @default.
- W2065955394 hasOpenAccess W2065955394 @default.
- W2065955394 hasPrimaryLocation W20659553941 @default.
- W2065955394 hasRelatedWork W112590946 @default.
- W2065955394 hasRelatedWork W1966583389 @default.
- W2065955394 hasRelatedWork W2011010934 @default.
- W2065955394 hasRelatedWork W2047608102 @default.
- W2065955394 hasRelatedWork W2065955394 @default.
- W2065955394 hasRelatedWork W2077998387 @default.
- W2065955394 hasRelatedWork W2126797993 @default.
- W2065955394 hasRelatedWork W2149410839 @default.
- W2065955394 hasRelatedWork W2190649397 @default.
- W2065955394 hasRelatedWork W3142254931 @default.
- W2065955394 hasVolume "57" @default.
- W2065955394 isParatext "false" @default.
- W2065955394 isRetracted "false" @default.
- W2065955394 magId "2065955394" @default.
- W2065955394 workType "article" @default.