FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2065960044> ?p ?o ?g. }

• W2065960044 endingPage "91" @default.
• W2065960044 startingPage "87" @default.
• W2065960044 abstract "Abstract Schistosoma mansoni infection is characterized by a strong T‐helper type 2 (Th2) cell‐associated immune response, but in the case of viral infection, it is associated with interferon‐gamma (IFN‐γ) increase and induction of Th1 immune response. Few data are available about the immune response of cases infected with combined hepatitis C virus (HCV) and schistosomiasis. Thus, the investigation of the cytokine pattern in patients coinfected with both HCV and Schistosoma mansoni was our rationale. This study included four patient groups: Group 1 included 20 patients infected with chronic HCV, Group 2 included 15 patients infected with schistosomiasis alone, Group 3 included 20 patients with chronic HCV and schistosomiasis and Group 4 included 15 healthy control individuals with matched age and sex. Serum levels of IFN‐γ, interleukin (IL)‐4, IL‐10 and IL‐18 were measured in all groups by enzyme‐linked immunosorbent assay. The results showed that the patients infected with HCV had significantly higher serum levels of IFN‐γ and IL‐18 compared with the controls and with the patients with schistosomiasis and coinfection ( P < 0.001). On the other hand, serum levels of IL‐4 and IL‐10 were significantly higher in patients with schistosomiasis and coinfection compared with the control group ( P < 0.001 and 0.0001, respectively) and with the HCV patients ( P < 0.05 and P < 0.001, respectively). A significant increase in serum levels of IL‐4 and IL‐10 was also found in HCV patients compared with the control ( P < 0.05). Schistosomiasis appears to induce a Th2 cytokine profile, with increase in serum levels of IL‐4 and IL‐10, even in the presence of HCV coinfection. In conclusion, schistosomiasis may downregulate the stimulatory effect of HCV on Th1 cytokines and this may lead to the chronicity of HCV infection in coinfected patients." @default.
• W2065960044 created "2016-06-24" @default.
• W2065960044 creator A5004715836 @default.
• W2065960044 creator A5011520858 @default.
• W2065960044 creator A5034268355 @default.
• W2065960044 creator A5054868481 @default.
• W2065960044 creator A5057121275 @default.
• W2065960044 date "2005-01-01" @default.
• W2065960044 modified "2023-10-15" @default.
• W2065960044 title "Interleukin (IL)-4, IL-10, IL-18 and IFN-gamma Cytokines Pattern in Patients with Combined Hepatitis C Virus and Schistosoma mansoni Infections" @default.
• W2065960044 cites W12293267 @default.
• W2065960044 cites W1513903598 @default.
• W2065960044 cites W1661510769 @default.
• W2065960044 cites W1855929178 @default.
• W2065960044 cites W1975021657 @default.
• W2065960044 cites W1991378085 @default.
• W2065960044 cites W1992987958 @default.
• W2065960044 cites W1994851922 @default.
• W2065960044 cites W1995483624 @default.
• W2065960044 cites W1996743123 @default.
• W2065960044 cites W2005681218 @default.
• W2065960044 cites W2007119568 @default.
• W2065960044 cites W2033651674 @default.
• W2065960044 cites W2035640816 @default.
• W2065960044 cites W2056628895 @default.
• W2065960044 cites W2058359652 @default.
• W2065960044 cites W2065184397 @default.
• W2065960044 cites W2075251791 @default.
• W2065960044 cites W2088652197 @default.
• W2065960044 cites W2103481898 @default.
• W2065960044 cites W2112560263 @default.
• W2065960044 cites W2120297349 @default.
• W2065960044 cites W2124915074 @default.
• W2065960044 cites W2125587250 @default.
• W2065960044 cites W2134337203 @default.
• W2065960044 cites W2176121499 @default.
• W2065960044 cites W2413638761 @default.
• W2065960044 cites W2619485555 @default.
• W2065960044 doi "https://doi.org/10.1111/j.0300-9475.2005.01529.x" @default.
• W2065960044 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15644127" @default.
• W2065960044 hasPublicationYear "2005" @default.
• W2065960044 type Work @default.
• W2065960044 sameAs 2065960044 @default.
• W2065960044 citedByCount "35" @default.
• W2065960044 countsByYear W20659600442012 @default.
• W2065960044 countsByYear W20659600442013 @default.
• W2065960044 countsByYear W20659600442014 @default.
• W2065960044 countsByYear W20659600442016 @default.
• W2065960044 countsByYear W20659600442018 @default.
• W2065960044 countsByYear W20659600442019 @default.
• W2065960044 countsByYear W20659600442020 @default.
• W2065960044 countsByYear W20659600442021 @default.
• W2065960044 countsByYear W20659600442022 @default.
• W2065960044 crossrefType "journal-article" @default.
• W2065960044 hasAuthorship W2065960044A5004715836 @default.
• W2065960044 hasAuthorship W2065960044A5011520858 @default.
• W2065960044 hasAuthorship W2065960044A5034268355 @default.
• W2065960044 hasAuthorship W2065960044A5054868481 @default.
• W2065960044 hasAuthorship W2065960044A5057121275 @default.
• W2065960044 hasBestOaLocation W20659600441 @default.
• W2065960044 hasConcept C126322002 @default.
• W2065960044 hasConcept C159047783 @default.
• W2065960044 hasConcept C165901193 @default.
• W2065960044 hasConcept C203014093 @default.
• W2065960044 hasConcept C2522874641 @default.
• W2065960044 hasConcept C2776178377 @default.
• W2065960044 hasConcept C2776225656 @default.
• W2065960044 hasConcept C2776408679 @default.
• W2065960044 hasConcept C2776863245 @default.
• W2065960044 hasConcept C2777813720 @default.
• W2065960044 hasConcept C2778491710 @default.
• W2065960044 hasConcept C2778690821 @default.
• W2065960044 hasConcept C71924100 @default.
• W2065960044 hasConcept C74172505 @default.
• W2065960044 hasConcept C8891405 @default.
• W2065960044 hasConcept C90924648 @default.
• W2065960044 hasConceptScore W2065960044C126322002 @default.
• W2065960044 hasConceptScore W2065960044C159047783 @default.
• W2065960044 hasConceptScore W2065960044C165901193 @default.
• W2065960044 hasConceptScore W2065960044C203014093 @default.
• W2065960044 hasConceptScore W2065960044C2522874641 @default.
• W2065960044 hasConceptScore W2065960044C2776178377 @default.
• W2065960044 hasConceptScore W2065960044C2776225656 @default.
• W2065960044 hasConceptScore W2065960044C2776408679 @default.
• W2065960044 hasConceptScore W2065960044C2776863245 @default.
• W2065960044 hasConceptScore W2065960044C2777813720 @default.
• W2065960044 hasConceptScore W2065960044C2778491710 @default.
• W2065960044 hasConceptScore W2065960044C2778690821 @default.
• W2065960044 hasConceptScore W2065960044C71924100 @default.
• W2065960044 hasConceptScore W2065960044C74172505 @default.
• W2065960044 hasConceptScore W2065960044C8891405 @default.
• W2065960044 hasConceptScore W2065960044C90924648 @default.
• W2065960044 hasIssue "1" @default.
• W2065960044 hasLocation W20659600441 @default.
• W2065960044 hasLocation W20659600442 @default.
• W2065960044 hasOpenAccess W2065960044 @default.
• W2065960044 hasPrimaryLocation W20659600441 @default.
• W2065960044 hasRelatedWork W1882698718 @default.

• next