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• W2065963780 abstract "Compounds (1–6) isolated from the CH2Cl2 extract of Glycyrrhiza inflata and semisynthetic licochalcone A derivatives (7–14) were evaluated for their protein tyrosine phosphatase 1B (PTP1B) inhibitory activities. Licochalcones A (4) and E (6), each with an allyl group at position 5 in the B ring exhibited significant inhibitory effects. Licochalcone A derivative 7, the most potent among the series, had an IC50 value of 11.7 ± 2.0 μM, ca. twofold better than that of licochalcone A (4)." @default.
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• W2065963780 date "2009-09-01" @default.
• W2065963780 modified "2023-10-16" @default.
• W2065963780 title "Inhibitory effect of chalcones and their derivatives from Glycyrrhiza inflata on protein tyrosine phosphatase 1B" @default.
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• W2065963780 doi "https://doi.org/10.1016/j.bmcl.2009.07.054" @default.
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