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- W2065963946 abstract "The orthopalladation of methyl arylglycinate derivatives has been studied. The reaction proceeds efficiently for different electron-withdrawing and electron-releasing substituents at the aryl ring. The carbonylation of the orthopalladated complexes affords, in a single step, substituted (1H)-isoindolin-1-one-3-carboxylates. These compounds constitute valuable synthetic intermediates and can be transformed diastereoselectively into octahydroisoindole-1-carboxylic acid derivatives, an important scaffold in the synthesis of many biologically active compounds." @default.
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- W2065963946 date "2011-06-01" @default.
- W2065963946 modified "2023-10-18" @default.
- W2065963946 title "Efficient access to (1H)-isoindolin-1-one-3-carboxylic acid derivatives by orthopalladation and carbonylation of methyl arylglycinate substrates" @default.
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- W2065963946 doi "https://doi.org/10.1016/j.tet.2011.04.064" @default.
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