Matches in SemOpenAlex for { <https://semopenalex.org/work/W2065985537> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2065985537 endingPage "67" @default.
- W2065985537 startingPage "59" @default.
- W2065985537 abstract "The effects of the combined exposure of cypermethrin (CY), NaAsO2 (As), and HgCl2 (Hg) were investigated in male Wistar rats following 4 weeks of oral exposure. Standard toxicological (body weight gain, organ weights of brain, thymus, heart, lung, liver, kidneys, adrenals, testes, and popliteal lymph node), haematological (white blood cell, red blood cell, haematocrit, MCV-mean volume of red blood cells, and cell content of the femoral bone marrow), and immune function (IgM-PFC response, delayed type hypersensitivity (DTH) reaction) parameters were measured. The two doses selected for the combination were: a high (H) dose equal to lowest observed effect level determined in preliminary experiments (CY(H)=55.4 mg/kg, As(H)=13.3 mg/kg, Hg(H)=3.20 mg/kg), and a low (L) dose which was ineffective (non-observed effect level); CY(L)=11.1 mg/kg, As(L)=3.33 mg/kg, Hg(L)=0.40 mg/kg). CY(H) was combined with As(L) or Hg(L), and the H doses of the heavy metals were combined with CY(L). Beside vehicle control, the H dose components of the combinations were also used as internal controls. The main finding of this study was that certain combinations, when compared to H dose internal control, significantly altered the body weight gain (As(H)+CY(L)), the relative weight of adrenals and popliteal lymph node (CY(H)+As(L) and CY(H)+Hg(L)), the cell content of the femoral bone marrow (CY(H)+Hg(L)), and the time course of DTH reaction (CY(H)+As(L)). According to the present results, combined exposure with CY and the heavy metals investigated can modify the toxicity and/or the functional detection limit of the single substances." @default.
- W2065985537 created "2016-06-24" @default.
- W2065985537 creator A5000430267 @default.
- W2065985537 creator A5006299082 @default.
- W2065985537 creator A5021335713 @default.
- W2065985537 creator A5075911470 @default.
- W2065985537 creator A5054623464 @default.
- W2065985537 date "2002-03-01" @default.
- W2065985537 modified "2023-10-17" @default.
- W2065985537 title "Immunotoxicological investigation in rats dosed repeatedly with combinations of cypermethrin, As(III), and Hg(II)" @default.
- W2065985537 cites W1569269680 @default.
- W2065985537 cites W1966942592 @default.
- W2065985537 cites W1993256799 @default.
- W2065985537 cites W1994978485 @default.
- W2065985537 cites W1997986244 @default.
- W2065985537 cites W2013000107 @default.
- W2065985537 cites W2023336870 @default.
- W2065985537 cites W2024337319 @default.
- W2065985537 cites W2025866984 @default.
- W2065985537 cites W2030415449 @default.
- W2065985537 cites W2031336940 @default.
- W2065985537 cites W2041891129 @default.
- W2065985537 cites W2043797906 @default.
- W2065985537 cites W2064614913 @default.
- W2065985537 cites W2064960956 @default.
- W2065985537 cites W2074619178 @default.
- W2065985537 cites W2137614038 @default.
- W2065985537 cites W2160724728 @default.
- W2065985537 cites W4234953386 @default.
- W2065985537 cites W4245299760 @default.
- W2065985537 doi "https://doi.org/10.1016/s0300-483x(01)00589-3" @default.
- W2065985537 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11844615" @default.
- W2065985537 hasPublicationYear "2002" @default.
- W2065985537 type Work @default.
- W2065985537 sameAs 2065985537 @default.
- W2065985537 citedByCount "13" @default.
- W2065985537 countsByYear W20659855372012 @default.
- W2065985537 countsByYear W20659855372013 @default.
- W2065985537 countsByYear W20659855372015 @default.
- W2065985537 countsByYear W20659855372018 @default.
- W2065985537 countsByYear W20659855372019 @default.
- W2065985537 countsByYear W20659855372020 @default.
- W2065985537 crossrefType "journal-article" @default.
- W2065985537 hasAuthorship W2065985537A5000430267 @default.
- W2065985537 hasAuthorship W2065985537A5006299082 @default.
- W2065985537 hasAuthorship W2065985537A5021335713 @default.
- W2065985537 hasAuthorship W2065985537A5054623464 @default.
- W2065985537 hasAuthorship W2065985537A5075911470 @default.
- W2065985537 hasConcept C126322002 @default.
- W2065985537 hasConcept C134018914 @default.
- W2065985537 hasConcept C142724271 @default.
- W2065985537 hasConcept C147583825 @default.
- W2065985537 hasConcept C185592680 @default.
- W2065985537 hasConcept C203014093 @default.
- W2065985537 hasConcept C2776557347 @default.
- W2065985537 hasConcept C2778488018 @default.
- W2065985537 hasConcept C2779720271 @default.
- W2065985537 hasConcept C2780007613 @default.
- W2065985537 hasConcept C2780849966 @default.
- W2065985537 hasConcept C29730261 @default.
- W2065985537 hasConcept C55493867 @default.
- W2065985537 hasConcept C71924100 @default.
- W2065985537 hasConcept C8891405 @default.
- W2065985537 hasConceptScore W2065985537C126322002 @default.
- W2065985537 hasConceptScore W2065985537C134018914 @default.
- W2065985537 hasConceptScore W2065985537C142724271 @default.
- W2065985537 hasConceptScore W2065985537C147583825 @default.
- W2065985537 hasConceptScore W2065985537C185592680 @default.
- W2065985537 hasConceptScore W2065985537C203014093 @default.
- W2065985537 hasConceptScore W2065985537C2776557347 @default.
- W2065985537 hasConceptScore W2065985537C2778488018 @default.
- W2065985537 hasConceptScore W2065985537C2779720271 @default.
- W2065985537 hasConceptScore W2065985537C2780007613 @default.
- W2065985537 hasConceptScore W2065985537C2780849966 @default.
- W2065985537 hasConceptScore W2065985537C29730261 @default.
- W2065985537 hasConceptScore W2065985537C55493867 @default.
- W2065985537 hasConceptScore W2065985537C71924100 @default.
- W2065985537 hasConceptScore W2065985537C8891405 @default.
- W2065985537 hasIssue "1" @default.
- W2065985537 hasLocation W20659855371 @default.
- W2065985537 hasLocation W20659855372 @default.
- W2065985537 hasOpenAccess W2065985537 @default.
- W2065985537 hasPrimaryLocation W20659855371 @default.
- W2065985537 hasRelatedWork W2010195523 @default.
- W2065985537 hasRelatedWork W2013644072 @default.
- W2065985537 hasRelatedWork W2014830377 @default.
- W2065985537 hasRelatedWork W2038737163 @default.
- W2065985537 hasRelatedWork W2063763413 @default.
- W2065985537 hasRelatedWork W2083356030 @default.
- W2065985537 hasRelatedWork W2130337422 @default.
- W2065985537 hasRelatedWork W2152437371 @default.
- W2065985537 hasRelatedWork W226467497 @default.
- W2065985537 hasRelatedWork W2473523216 @default.
- W2065985537 hasVolume "172" @default.
- W2065985537 isParatext "false" @default.
- W2065985537 isRetracted "false" @default.
- W2065985537 magId "2065985537" @default.
- W2065985537 workType "article" @default.