Matches in SemOpenAlex for { <https://semopenalex.org/work/W2065987588> ?p ?o ?g. }
- W2065987588 endingPage "110" @default.
- W2065987588 startingPage "101" @default.
- W2065987588 abstract "The effects of graded amounts of dietary sitostanol (0.01, 0.2 and 0.8% (w/w)) were examined on plasma lipid-profile, coronary artery plaque development and lecithin:cholesterol acyl transferase activity in male New Zealand White rabbits given semi-purified diets for 10 weeks. All diets provided <10% energy in the form of fat and contained 0.5% (w/w) cholesterol (C). Rabbits fed the semi-purified diet with 0.8% (w/w) (0.64 g/day) sitostanol had lower plasma total cholesterol (TC) (p=0.006) (15.2±4.80 mmol/l) and very low-density lipoprotein-cholesterol (VLDL-C) (p=0.007) (6.31±3.11 mmol/l) levels compared to the atherogenic control group (n=6) (29.6±5.52 and 17.16±7.43 mmol/l, respectively). Dietary sitostanol at 0.8% (w/w) depressed plaque accretion in coronary arteries (p=0.0014) and ascending aorta (p=0.0004) compared with the atherogenic control, 0.01 and 0.2% (w/w) sitostanol-fed groups. No differences (p=0.24) in the activity of lecithin:cholesterol acyl transferase (LCAT) were observed across groups, although plasma cholesterol fractional esterification rate was higher (p=0.004) in the 0.8% (w/w) sitostanol fed animals compared with the atherogenic control. Significant negative correlations were demonstrated between sitostanol intake and plasma TC, LDL-C and VLDL-C levels. Hepatic campesterol levels were correlated (r=0.3, p=0.03) with plasma but not hepatic TC concentrations. These results demonstrate that dietary sitostanol at a concentration of 0.8% (w/w) or 0.64 g/day lowered plasma cholesterol levels and depressed atherosclerosis development in rabbits, but did not alter LCAT activity." @default.
- W2065987588 created "2016-06-24" @default.
- W2065987588 creator A5013333375 @default.
- W2065987588 creator A5072726873 @default.
- W2065987588 creator A5074124714 @default.
- W2065987588 date "1998-05-01" @default.
- W2065987588 modified "2023-09-26" @default.
- W2065987588 title "Dietary sitostanol reduces plaque formation but not lecithin cholesterol acyl transferase activity in rabbits" @default.
- W2065987588 cites W13663154 @default.
- W2065987588 cites W143383438 @default.
- W2065987588 cites W1826581037 @default.
- W2065987588 cites W1855422631 @default.
- W2065987588 cites W1856177890 @default.
- W2065987588 cites W1859370186 @default.
- W2065987588 cites W1864556716 @default.
- W2065987588 cites W1963535962 @default.
- W2065987588 cites W1964916455 @default.
- W2065987588 cites W1970591114 @default.
- W2065987588 cites W1974439863 @default.
- W2065987588 cites W1974942098 @default.
- W2065987588 cites W1984689768 @default.
- W2065987588 cites W2006038444 @default.
- W2065987588 cites W2015179729 @default.
- W2065987588 cites W2022504847 @default.
- W2065987588 cites W2023979557 @default.
- W2065987588 cites W2029705159 @default.
- W2065987588 cites W2041654885 @default.
- W2065987588 cites W2052853044 @default.
- W2065987588 cites W2059283688 @default.
- W2065987588 cites W2062364166 @default.
- W2065987588 cites W2067102851 @default.
- W2065987588 cites W2076631255 @default.
- W2065987588 cites W2079031529 @default.
- W2065987588 cites W2080817210 @default.
- W2065987588 cites W2084568049 @default.
- W2065987588 cites W2092898701 @default.
- W2065987588 cites W2095183812 @default.
- W2065987588 cites W2099870084 @default.
- W2065987588 cites W2110350695 @default.
- W2065987588 cites W2124804571 @default.
- W2065987588 cites W2128086186 @default.
- W2065987588 cites W2147985004 @default.
- W2065987588 cites W2151555917 @default.
- W2065987588 cites W2157021932 @default.
- W2065987588 cites W2162450762 @default.
- W2065987588 cites W2166241950 @default.
- W2065987588 cites W2167760025 @default.
- W2065987588 cites W2183900551 @default.
- W2065987588 cites W2185622151 @default.
- W2065987588 cites W2242402885 @default.
- W2065987588 cites W2254303121 @default.
- W2065987588 cites W2321309958 @default.
- W2065987588 cites W2409332510 @default.
- W2065987588 cites W334600772 @default.
- W2065987588 cites W4239595870 @default.
- W2065987588 cites W4254025868 @default.
- W2065987588 doi "https://doi.org/10.1016/s0021-9150(98)00008-2" @default.
- W2065987588 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9678775" @default.
- W2065987588 hasPublicationYear "1998" @default.
- W2065987588 type Work @default.
- W2065987588 sameAs 2065987588 @default.
- W2065987588 citedByCount "62" @default.
- W2065987588 countsByYear W20659875882012 @default.
- W2065987588 countsByYear W20659875882013 @default.
- W2065987588 countsByYear W20659875882014 @default.
- W2065987588 countsByYear W20659875882015 @default.
- W2065987588 countsByYear W20659875882019 @default.
- W2065987588 countsByYear W20659875882022 @default.
- W2065987588 crossrefType "journal-article" @default.
- W2065987588 hasAuthorship W2065987588A5013333375 @default.
- W2065987588 hasAuthorship W2065987588A5072726873 @default.
- W2065987588 hasAuthorship W2065987588A5074124714 @default.
- W2065987588 hasConcept C126322002 @default.
- W2065987588 hasConcept C134018914 @default.
- W2065987588 hasConcept C185592680 @default.
- W2065987588 hasConcept C2778163477 @default.
- W2065987588 hasConcept C2778718757 @default.
- W2065987588 hasConcept C2779564620 @default.
- W2065987588 hasConcept C2780072125 @default.
- W2065987588 hasConcept C2781471481 @default.
- W2065987588 hasConcept C37002583 @default.
- W2065987588 hasConcept C55493867 @default.
- W2065987588 hasConcept C71924100 @default.
- W2065987588 hasConcept C8243546 @default.
- W2065987588 hasConcept C86803240 @default.
- W2065987588 hasConceptScore W2065987588C126322002 @default.
- W2065987588 hasConceptScore W2065987588C134018914 @default.
- W2065987588 hasConceptScore W2065987588C185592680 @default.
- W2065987588 hasConceptScore W2065987588C2778163477 @default.
- W2065987588 hasConceptScore W2065987588C2778718757 @default.
- W2065987588 hasConceptScore W2065987588C2779564620 @default.
- W2065987588 hasConceptScore W2065987588C2780072125 @default.
- W2065987588 hasConceptScore W2065987588C2781471481 @default.
- W2065987588 hasConceptScore W2065987588C37002583 @default.
- W2065987588 hasConceptScore W2065987588C55493867 @default.
- W2065987588 hasConceptScore W2065987588C71924100 @default.
- W2065987588 hasConceptScore W2065987588C8243546 @default.
- W2065987588 hasConceptScore W2065987588C86803240 @default.