Matches in SemOpenAlex for { <https://semopenalex.org/work/W2065995152> ?p ?o ?g. }
- W2065995152 endingPage "427" @default.
- W2065995152 startingPage "417" @default.
- W2065995152 abstract "Induction of IL-12 and IL-23 is essential for protective immunity against Cryptococcusneoformans. The contribution of dendritic cells vs. macrophages to IL-12/23 production in response to C. neoformans infection is unclear. Activation of conventional bone marrow-derived dendritic cells (BMDC), plasmacytoid BMDC, and bone marrow-derived macrophages (BMMPhi) was assessed by analyzing cytokine responses and the expression of MHC-II, CD86, and CD80 in each cell type. Cryptococcus neoformans induced the release of IL-12/23p40 by BMDC, but not by BMMPhi, in a TLR2- and TLR4-independent but MyD88-dependent manner. Conventional BMDC rather than plasmacytoid BMDC up-regulated MHC-II and CD86, while BMMPhi down-regulated MHC-II and CD86 in response to C. neoformans. The up-regulation of MHC-II and CD86 on BMDC required MyD88. Our data point to conventional DC as critical IL-12/23-producing antigen-presenting cells during cryptococcosis." @default.
- W2065995152 created "2016-06-24" @default.
- W2065995152 creator A5027011664 @default.
- W2065995152 creator A5068754475 @default.
- W2065995152 date "2008-04-01" @default.
- W2065995152 modified "2023-09-25" @default.
- W2065995152 title "<i>Cryptococcus neoformans</i>activates bone marrow-derived conventional dendritic cells rather than plasmacytoid dendritic cells and down-regulates macrophages" @default.
- W2065995152 cites W1514540900 @default.
- W2065995152 cites W1517310071 @default.
- W2065995152 cites W1538844879 @default.
- W2065995152 cites W1585461212 @default.
- W2065995152 cites W1900738890 @default.
- W2065995152 cites W1957937071 @default.
- W2065995152 cites W1962480635 @default.
- W2065995152 cites W1963964762 @default.
- W2065995152 cites W1964909764 @default.
- W2065995152 cites W1967879964 @default.
- W2065995152 cites W1968595840 @default.
- W2065995152 cites W1970291282 @default.
- W2065995152 cites W1972776583 @default.
- W2065995152 cites W1973645415 @default.
- W2065995152 cites W1988604605 @default.
- W2065995152 cites W1992439632 @default.
- W2065995152 cites W2036767516 @default.
- W2065995152 cites W2038181477 @default.
- W2065995152 cites W2047329367 @default.
- W2065995152 cites W2079203244 @default.
- W2065995152 cites W2092235636 @default.
- W2065995152 cites W2092296681 @default.
- W2065995152 cites W2093508027 @default.
- W2065995152 cites W2094373273 @default.
- W2065995152 cites W2099456939 @default.
- W2065995152 cites W2102642516 @default.
- W2065995152 cites W2105618135 @default.
- W2065995152 cites W2109854599 @default.
- W2065995152 cites W2114056484 @default.
- W2065995152 cites W2126397566 @default.
- W2065995152 cites W2127537536 @default.
- W2065995152 cites W2130652971 @default.
- W2065995152 cites W2146171603 @default.
- W2065995152 cites W2149082099 @default.
- W2065995152 cites W2149134249 @default.
- W2065995152 cites W2150004345 @default.
- W2065995152 cites W2153517890 @default.
- W2065995152 cites W2161472648 @default.
- W2065995152 cites W2162283041 @default.
- W2065995152 cites W4230023451 @default.
- W2065995152 cites W2136368552 @default.
- W2065995152 doi "https://doi.org/10.1111/j.1574-695x.2008.00391.x" @default.
- W2065995152 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18336384" @default.
- W2065995152 hasPublicationYear "2008" @default.
- W2065995152 type Work @default.
- W2065995152 sameAs 2065995152 @default.
- W2065995152 citedByCount "26" @default.
- W2065995152 countsByYear W20659951522012 @default.
- W2065995152 countsByYear W20659951522013 @default.
- W2065995152 countsByYear W20659951522014 @default.
- W2065995152 countsByYear W20659951522015 @default.
- W2065995152 countsByYear W20659951522016 @default.
- W2065995152 countsByYear W20659951522017 @default.
- W2065995152 countsByYear W20659951522018 @default.
- W2065995152 countsByYear W20659951522023 @default.
- W2065995152 crossrefType "journal-article" @default.
- W2065995152 hasAuthorship W2065995152A5027011664 @default.
- W2065995152 hasAuthorship W2065995152A5068754475 @default.
- W2065995152 hasConcept C154317977 @default.
- W2065995152 hasConcept C202751555 @default.
- W2065995152 hasConcept C203014093 @default.
- W2065995152 hasConcept C207936829 @default.
- W2065995152 hasConcept C2776070231 @default.
- W2065995152 hasConcept C2776090121 @default.
- W2065995152 hasConcept C2777893358 @default.
- W2065995152 hasConcept C2778170410 @default.
- W2065995152 hasConcept C2778297628 @default.
- W2065995152 hasConcept C2778690821 @default.
- W2065995152 hasConcept C2778814158 @default.
- W2065995152 hasConcept C2780007613 @default.
- W2065995152 hasConcept C2781101188 @default.
- W2065995152 hasConcept C2781236682 @default.
- W2065995152 hasConcept C39347974 @default.
- W2065995152 hasConcept C55493867 @default.
- W2065995152 hasConcept C86803240 @default.
- W2065995152 hasConcept C8891405 @default.
- W2065995152 hasConcept C89423630 @default.
- W2065995152 hasConcept C95444343 @default.
- W2065995152 hasConceptScore W2065995152C154317977 @default.
- W2065995152 hasConceptScore W2065995152C202751555 @default.
- W2065995152 hasConceptScore W2065995152C203014093 @default.
- W2065995152 hasConceptScore W2065995152C207936829 @default.
- W2065995152 hasConceptScore W2065995152C2776070231 @default.
- W2065995152 hasConceptScore W2065995152C2776090121 @default.
- W2065995152 hasConceptScore W2065995152C2777893358 @default.
- W2065995152 hasConceptScore W2065995152C2778170410 @default.
- W2065995152 hasConceptScore W2065995152C2778297628 @default.
- W2065995152 hasConceptScore W2065995152C2778690821 @default.
- W2065995152 hasConceptScore W2065995152C2778814158 @default.
- W2065995152 hasConceptScore W2065995152C2780007613 @default.
- W2065995152 hasConceptScore W2065995152C2781101188 @default.