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- W2066018560 abstract "Temperature-sensitive (ts) mutations occurring in three genes, 1, 2, and 7, and 1, 5 and 7 were found in two cold-adapted (ts) attenuated influenza virus strains A/Leningrad/9/37/46 (H0N1) and A/Leningrad/134/17/57 (H2N2) respectively. The recombinants, obtained by crossing these cold-adapted strains with virulent influenza virus strains, had different genome structures and inherited from one to six genes from the cold-adapted parents. Tests of reactogenicity of recombinants in volunteers showed all the recombinants to be non-reactogenic irrespective of the number of genes inherited from the cold-adapted parent." @default.
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- W2066018560 date "1981-04-01" @default.
- W2066018560 modified "2023-09-27" @default.
- W2066018560 title "Analysis of Genome Composition and Reactogenicity of Recombinants of Cold-adapted and Virulent Virus Strains" @default.
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- W2066018560 doi "https://doi.org/10.1099/0022-1317-53-2-215" @default.
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