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• W2066018873 endingPage "58" @default.
• W2066018873 startingPage "44" @default.
• W2066018873 abstract "Chemokines belong to a family of chemotactic cytokines that direct the migration of immune cells towards sites of inflammation. They mediate their biological effects by binding to cell surface receptors, which belong to the G protein-coupled receptor superfamily. Since chemokines and their receptors have been implicated in the pathophysiology of a number of autoinflammatory diseases, chemokine receptor antagonists could prove to be useful therapeutics to target these diseases. Here, we review the role of chemokines in autoimmunity, concentrating mainly on the chemokine receptors CCR1 and CCR5, and discuss the potential utility of antagonists that target these 2 receptors as they progress through the clinic." @default.
• W2066018873 created "2016-06-24" @default.
• W2066018873 creator A5051170989 @default.
• W2066018873 creator A5060513190 @default.
• W2066018873 date "2005-07-01" @default.
• W2066018873 modified "2023-09-23" @default.
• W2066018873 title "The clinical potential of chemokine receptor antagonists" @default.
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• W2066018873 doi "https://doi.org/10.1016/j.pharmthera.2005.01.004" @default.
• W2066018873 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15894378" @default.

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