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- W2066052259 abstract "Eosinophilic esophagitis (EoE) is increasingly diagnosed as a disorder throughout the world. It is characterized by eosinophils in the esophagus due to food allergies. Molecular analysis of esophageal biopsies and mouse models have indicated a clear role for the T helper 2 pathway, in particular interleukins 5 and 13, in this disease. Current treatment options for EoE involve avoidance of the allergens or using anti-inflammatory medications such as topical corticosteroids. In the past year, genomic research has led to the identification of single nucleotide polymorphisms in the gene encoding thymic stromal lymphopoietin (TSLP), and subsequently in the gene encoding its receptor, as disease susceptibility markers for EoE. Identification of this molecule and its receptor suggest the potential for new treatment options in the future." @default.
- W2066052259 created "2016-06-24" @default.
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- W2066052259 date "2010-01-01" @default.
- W2066052259 modified "2023-09-26" @default.
- W2066052259 title "New genetic links in eosinophilic esophagitis" @default.
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- W2066052259 doi "https://doi.org/10.1186/gm181" @default.
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