Matches in SemOpenAlex for { <https://semopenalex.org/work/W2066091591> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2066091591 abstract "Purpose: In-vivo dose and beam range verification in proton therapy could play significant roles in proton treatment validation and improvements. Invivo beam range verification, in particular, could enable new treatment techniques one of which, for example, could be the use of anterior fields for prostate treatment instead of opposed lateral fields as in current practice. We have developed and commissioned an integrated system with hardware, software and workflow protocols, to provide a complete solution, simultaneously for both in-vivo dosimetry and range verification for proton therapy. Methods: The system uses a matrix of diodes, up to 12 in total, but separable into three groups for flexibility in application. A special amplifier was developed to capture extremely small signals from very low proton beam current. The software was developed within iMagX, a general platform for image processing in radiation therapy applications. The range determination exploits the inherent relationship between the internal range modulation clock of the proton therapy system and the radiological depth at the point of measurement. The commissioning of the system, for in-vivo dosimetry and for range verification was separately conducted using anthropomorphic phantom. EBT films and TLDs were used for dose comparisons and range scan of the beam distal fall-off was used as ground truth for range verification. Results: For in-vivo dose measurement, the results were in agreement with TLD and EBT films and were within 3% from treatment planning calculations. For range verification, a precision of 0.5mm is achieved in homogeneous phantoms, and a precision of 2mm for anthropomorphic pelvic phantom, except at points with significant range mixing. Conclusion: We completed the commissioning of our system for in-vivo dosimetry and range verification in proton therapy. The results suggest that the system is ready for clinical trials on patient." @default.
- W2066091591 created "2016-06-24" @default.
- W2066091591 creator A5014788611 @default.
- W2066091591 creator A5038276209 @default.
- W2066091591 creator A5043712361 @default.
- W2066091591 creator A5045122984 @default.
- W2066091591 creator A5046445659 @default.
- W2066091591 creator A5050270794 @default.
- W2066091591 creator A5054391338 @default.
- W2066091591 creator A5062865988 @default.
- W2066091591 creator A5067109674 @default.
- W2066091591 creator A5006643502 @default.
- W2066091591 date "2014-05-29" @default.
- W2066091591 modified "2023-09-25" @default.
- W2066091591 title "SU-E-T-435: Development and Commissioning of a Complete System for In-Vivo Dosimetry and Range Verification in Proton Therapy" @default.
- W2066091591 doi "https://doi.org/10.1118/1.4888768" @default.
- W2066091591 hasPublicationYear "2014" @default.
- W2066091591 type Work @default.
- W2066091591 sameAs 2066091591 @default.
- W2066091591 citedByCount "0" @default.
- W2066091591 crossrefType "journal-article" @default.
- W2066091591 hasAuthorship W2066091591A5006643502 @default.
- W2066091591 hasAuthorship W2066091591A5014788611 @default.
- W2066091591 hasAuthorship W2066091591A5038276209 @default.
- W2066091591 hasAuthorship W2066091591A5043712361 @default.
- W2066091591 hasAuthorship W2066091591A5045122984 @default.
- W2066091591 hasAuthorship W2066091591A5046445659 @default.
- W2066091591 hasAuthorship W2066091591A5050270794 @default.
- W2066091591 hasAuthorship W2066091591A5054391338 @default.
- W2066091591 hasAuthorship W2066091591A5062865988 @default.
- W2066091591 hasAuthorship W2066091591A5067109674 @default.
- W2066091591 hasConcept C104293457 @default.
- W2066091591 hasConcept C105636585 @default.
- W2066091591 hasConcept C120665830 @default.
- W2066091591 hasConcept C121332964 @default.
- W2066091591 hasConcept C126838900 @default.
- W2066091591 hasConcept C148325268 @default.
- W2066091591 hasConcept C168834538 @default.
- W2066091591 hasConcept C19527891 @default.
- W2066091591 hasConcept C201645570 @default.
- W2066091591 hasConcept C2779244869 @default.
- W2066091591 hasConcept C2781298738 @default.
- W2066091591 hasConcept C2989005 @default.
- W2066091591 hasConcept C41008148 @default.
- W2066091591 hasConcept C509974204 @default.
- W2066091591 hasConcept C71924100 @default.
- W2066091591 hasConcept C75088862 @default.
- W2066091591 hasConceptScore W2066091591C104293457 @default.
- W2066091591 hasConceptScore W2066091591C105636585 @default.
- W2066091591 hasConceptScore W2066091591C120665830 @default.
- W2066091591 hasConceptScore W2066091591C121332964 @default.
- W2066091591 hasConceptScore W2066091591C126838900 @default.
- W2066091591 hasConceptScore W2066091591C148325268 @default.
- W2066091591 hasConceptScore W2066091591C168834538 @default.
- W2066091591 hasConceptScore W2066091591C19527891 @default.
- W2066091591 hasConceptScore W2066091591C201645570 @default.
- W2066091591 hasConceptScore W2066091591C2779244869 @default.
- W2066091591 hasConceptScore W2066091591C2781298738 @default.
- W2066091591 hasConceptScore W2066091591C2989005 @default.
- W2066091591 hasConceptScore W2066091591C41008148 @default.
- W2066091591 hasConceptScore W2066091591C509974204 @default.
- W2066091591 hasConceptScore W2066091591C71924100 @default.
- W2066091591 hasConceptScore W2066091591C75088862 @default.
- W2066091591 hasLocation W20660915911 @default.
- W2066091591 hasOpenAccess W2066091591 @default.
- W2066091591 hasPrimaryLocation W20660915911 @default.
- W2066091591 hasRelatedWork W1966966942 @default.
- W2066091591 hasRelatedWork W1985283778 @default.
- W2066091591 hasRelatedWork W1991101907 @default.
- W2066091591 hasRelatedWork W2001931327 @default.
- W2066091591 hasRelatedWork W2016256026 @default.
- W2066091591 hasRelatedWork W2016482093 @default.
- W2066091591 hasRelatedWork W2035738446 @default.
- W2066091591 hasRelatedWork W2048694701 @default.
- W2066091591 hasRelatedWork W2051416680 @default.
- W2066091591 hasRelatedWork W2082016549 @default.
- W2066091591 hasRelatedWork W2082231375 @default.
- W2066091591 hasRelatedWork W2082484384 @default.
- W2066091591 hasRelatedWork W2151253091 @default.
- W2066091591 hasRelatedWork W2180593672 @default.
- W2066091591 hasRelatedWork W2460316283 @default.
- W2066091591 hasRelatedWork W2747840560 @default.
- W2066091591 hasRelatedWork W2902998872 @default.
- W2066091591 hasRelatedWork W2969077069 @default.
- W2066091591 hasRelatedWork W2977607786 @default.
- W2066091591 hasRelatedWork W2197575470 @default.
- W2066091591 isParatext "false" @default.
- W2066091591 isRetracted "false" @default.
- W2066091591 magId "2066091591" @default.
- W2066091591 workType "article" @default.