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• W2066135370 abstract "Abstract The purpose of this paper was to make a critical review of akathisia, based on the principles of evidence‐based medicine, and to explore a possible link between akathisia and suicidal behaviour (suicidal thinking, parasuicide and completed suicide). An extensive systematic search was carried out on three major databases, Embase, ClinPsych and Medline. Fifty‐seven relevant references were found, and a further 26 references were reviewed after careful selection from the references of the original references. The Cochrane Library did not contain any systematic reviews on the subject. Akathisia can be caused by several different groups of drugs, but most frequently by antipsychotics and to a lesser extent antidepressants. Research into akathisia is made considerably more difficult by the lack of a universally agreed definition of the condition. The underlying pathophysiology is still far from clear, but the literature offers guidelines on less hazardous management regimes for patients. On the basis of the existing literature, akathisia cannot at this stage unequivocally be linked to suicidal behaviour. It is certain, however, that the condition of akathisia does cause considerable distress in an already vulnerable group of patients. Because it is largely avoidable, new, more rigorous strategies must be put in place to prevent it. Copyright © 2001 John Wiley & Sons, Ltd." @default.
• W2066135370 created "2016-06-24" @default.
• W2066135370 creator A5062338352 @default.
• W2066135370 date "2001-09-12" @default.
• W2066135370 modified "2023-10-11" @default.
• W2066135370 title "A critical review of akathisia, and its possible association with suicidal behaviour" @default.
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• W2066135370 doi "https://doi.org/10.1002/hup.325" @default.
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