FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2066244040> ?p ?o ?g. }

• W2066244040 endingPage "17" @default.
• W2066244040 startingPage "1" @default.
• W2066244040 abstract "Drug dependence is a chronic, relapsing disorder in which compulsive drug-seeking and drug-taking behaviours persist despite serious negative consequences. Addictive substances, such as opioids, ethanol, psychostimulants and nicotine, induce pleasant states or relieve distress, effects that contribute to their recreational use. Dopamine is critically involved in drug addiction processes. However, the role of the various dopaminergic receptor subtypes has been difficult to delineate. Here, we will review the information collected implicating the receptors of the D1 family (DRD1 and DRD5) and of the D2 family (DRD2, DRD3 and DRD4) in drug addiction. We will summarize the distribution of these receptors in the brain, the preclinical experiments carried out with pharmacological and transgenic approaches and the genetic studies carried out linking genetic variants of these receptors to drug addiction phenotypes. A meta-analysis of the studies carried out evaluating DRD2 and alcohol dependence is also provided, which indicates a significant association. Overall, this review indicates that different aspects of the addiction phenotype are critically influenced by dopaminergic receptors and that variants of those genes seem to influence some addiction phenotypes in humans." @default.
• W2066244040 created "2016-06-24" @default.
• W2066244040 creator A5027044666 @default.
• W2066244040 creator A5038113594 @default.
• W2066244040 creator A5045198529 @default.
• W2066244040 creator A5072086960 @default.
• W2066244040 creator A5076987411 @default.
• W2066244040 date "2009-02-01" @default.
• W2066244040 modified "2023-09-30" @default.
• W2066244040 title "Genetics of dopamine receptors and drug addiction: a comprehensive review" @default.
• W2066244040 cites W120412258 @default.
• W2066244040 cites W1500701263 @default.
• W2066244040 cites W1546116904 @default.
• W2066244040 cites W1559989154 @default.
• W2066244040 cites W1568198343 @default.
• W2066244040 cites W1574751342 @default.
• W2066244040 cites W1595098454 @default.
• W2066244040 cites W1601690727 @default.
• W2066244040 cites W1612007229 @default.
• W2066244040 cites W1635375164 @default.
• W2066244040 cites W1817985333 @default.
• W2066244040 cites W1872057083 @default.
• W2066244040 cites W1913013241 @default.
• W2066244040 cites W1922752440 @default.
• W2066244040 cites W1922867421 @default.
• W2066244040 cites W1925492557 @default.
• W2066244040 cites W1963562655 @default.
• W2066244040 cites W1964344702 @default.
• W2066244040 cites W1964739293 @default.
• W2066244040 cites W1966092598 @default.
• W2066244040 cites W1966233483 @default.
• W2066244040 cites W1966795950 @default.
• W2066244040 cites W1968058954 @default.
• W2066244040 cites W1968250493 @default.
• W2066244040 cites W1969509559 @default.
• W2066244040 cites W1970128511 @default.
• W2066244040 cites W1971192317 @default.
• W2066244040 cites W1971417227 @default.
• W2066244040 cites W1971566792 @default.
• W2066244040 cites W1971933385 @default.
• W2066244040 cites W1973033677 @default.
• W2066244040 cites W1973101981 @default.
• W2066244040 cites W1973750276 @default.
• W2066244040 cites W1974311568 @default.
• W2066244040 cites W1974313171 @default.
• W2066244040 cites W1974321496 @default.
• W2066244040 cites W1974681763 @default.
• W2066244040 cites W1975977959 @default.
• W2066244040 cites W1975997144 @default.
• W2066244040 cites W1977428935 @default.
• W2066244040 cites W1977533543 @default.
• W2066244040 cites W1977918460 @default.
• W2066244040 cites W1978812567 @default.
• W2066244040 cites W1978850926 @default.
• W2066244040 cites W1979179687 @default.
• W2066244040 cites W1979596511 @default.
• W2066244040 cites W1980144781 @default.
• W2066244040 cites W1980344452 @default.
• W2066244040 cites W1980923784 @default.
• W2066244040 cites W1981579764 @default.
• W2066244040 cites W1981610383 @default.
• W2066244040 cites W1982411078 @default.
• W2066244040 cites W1983083650 @default.
• W2066244040 cites W1985582613 @default.
• W2066244040 cites W1985856611 @default.
• W2066244040 cites W1986009248 @default.
• W2066244040 cites W1986269606 @default.
• W2066244040 cites W1988560875 @default.
• W2066244040 cites W1990490435 @default.
• W2066244040 cites W1991154371 @default.
• W2066244040 cites W1991603311 @default.
• W2066244040 cites W1993105854 @default.
• W2066244040 cites W1993405308 @default.
• W2066244040 cites W1994181770 @default.
• W2066244040 cites W1996119435 @default.
• W2066244040 cites W1997031882 @default.
• W2066244040 cites W1998152406 @default.
• W2066244040 cites W1998271863 @default.
• W2066244040 cites W1998670974 @default.
• W2066244040 cites W1998819721 @default.
• W2066244040 cites W1999813581 @default.
• W2066244040 cites W1999964839 @default.
• W2066244040 cites W2001380147 @default.
• W2066244040 cites W2001566515 @default.
• W2066244040 cites W2001865657 @default.
• W2066244040 cites W2003692460 @default.
• W2066244040 cites W2005008592 @default.
• W2066244040 cites W2005897842 @default.
• W2066244040 cites W2006636385 @default.
• W2066244040 cites W2007597024 @default.
• W2066244040 cites W2009243814 @default.
• W2066244040 cites W2009784590 @default.
• W2066244040 cites W2010014315 @default.
• W2066244040 cites W2010312082 @default.
• W2066244040 cites W2010511773 @default.
• W2066244040 cites W2010711917 @default.
• W2066244040 cites W2011256883 @default.
• W2066244040 cites W2011492524 @default.

• next