FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2066257706> ?p ?o ?g. }

• W2066257706 abstract "Acute lung injury (ALI) is a critical illness syndrome with a mortality rate of 25-40%. Despite recent advances of our understanding of the pathophysiology of ALI, no pharmacologic therapies have been proven effective. The key pathogenesis of ALI is the activation of the coagulation cascade and impaired fibrinolysis, resulting in extensive fibrin and hyaline membrane deposition. Activated protein C (APC), an endogenous protein that promotes fibrinolysis and inhibits thrombosis, can modulate the coagulation and inflammation associated with ALI. It is therefore reasonable to suggest that preventing the progression of pulmonary coagulopathy, by restoring normal intraalveolar levels of protein C, will be of therapeutic benefit to patients with ALI. However, a recent clinical trial demonstrated that APC did not improve outcomes from ALI, raising the possibility that the method of APC administration, intravenous infusion or inhalation, may influence the outcomes. In this article we propose the hypothesis that APC inhalation might be a promising and novel choice in the treatment of ALI." @default.
• W2066257706 created "2016-06-24" @default.
• W2066257706 creator A5003396916 @default.
• W2066257706 creator A5022366712 @default.
• W2066257706 creator A5032475838 @default.
• W2066257706 creator A5043022302 @default.
• W2066257706 creator A5069673018 @default.
• W2066257706 creator A5079104533 @default.
• W2066257706 date "2011-01-01" @default.
• W2066257706 modified "2023-09-26" @default.
• W2066257706 title "Activated protein C inhalation: A novel therapeutic strategy for acute lung injury" @default.
• W2066257706 cites W1685198220 @default.
• W2066257706 cites W1980233581 @default.
• W2066257706 cites W1985455915 @default.
• W2066257706 cites W2007327258 @default.
• W2066257706 cites W2008830288 @default.
• W2066257706 cites W2068854215 @default.
• W2066257706 cites W2074488392 @default.
• W2066257706 cites W2078539387 @default.
• W2066257706 cites W2107997329 @default.
• W2066257706 cites W2108664084 @default.
• W2066257706 cites W2132816829 @default.
• W2066257706 cites W2142994668 @default.
• W2066257706 cites W2154611259 @default.
• W2066257706 cites W2157059584 @default.
• W2066257706 cites W2159487576 @default.
• W2066257706 cites W2170885626 @default.
• W2066257706 cites W2322121630 @default.
• W2066257706 doi "https://doi.org/10.12659/msm.881789" @default.
• W2066257706 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3539554" @default.
• W2066257706 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21629195" @default.
• W2066257706 hasPublicationYear "2011" @default.
• W2066257706 type Work @default.
• W2066257706 sameAs 2066257706 @default.
• W2066257706 citedByCount "4" @default.
• W2066257706 countsByYear W20662577062012 @default.
• W2066257706 countsByYear W20662577062014 @default.
• W2066257706 countsByYear W20662577062020 @default.
• W2066257706 crossrefType "journal-article" @default.
• W2066257706 hasAuthorship W2066257706A5003396916 @default.
• W2066257706 hasAuthorship W2066257706A5022366712 @default.
• W2066257706 hasAuthorship W2066257706A5032475838 @default.
• W2066257706 hasAuthorship W2066257706A5043022302 @default.
• W2066257706 hasAuthorship W2066257706A5069673018 @default.
• W2066257706 hasAuthorship W2066257706A5079104533 @default.
• W2066257706 hasBestOaLocation W20662577062 @default.
• W2066257706 hasConcept C126322002 @default.
• W2066257706 hasConcept C203014093 @default.
• W2066257706 hasConcept C2776825266 @default.
• W2066257706 hasConcept C2776914184 @default.
• W2066257706 hasConcept C2776954882 @default.
• W2066257706 hasConcept C2778382381 @default.
• W2066257706 hasConcept C2779936836 @default.
• W2066257706 hasConcept C2780942790 @default.
• W2066257706 hasConcept C2781287897 @default.
• W2066257706 hasConcept C42219234 @default.
• W2066257706 hasConcept C54173615 @default.
• W2066257706 hasConcept C71924100 @default.
• W2066257706 hasConcept C98274493 @default.
• W2066257706 hasConceptScore W2066257706C126322002 @default.
• W2066257706 hasConceptScore W2066257706C203014093 @default.
• W2066257706 hasConceptScore W2066257706C2776825266 @default.
• W2066257706 hasConceptScore W2066257706C2776914184 @default.
• W2066257706 hasConceptScore W2066257706C2776954882 @default.
• W2066257706 hasConceptScore W2066257706C2778382381 @default.
• W2066257706 hasConceptScore W2066257706C2779936836 @default.
• W2066257706 hasConceptScore W2066257706C2780942790 @default.
• W2066257706 hasConceptScore W2066257706C2781287897 @default.
• W2066257706 hasConceptScore W2066257706C42219234 @default.
• W2066257706 hasConceptScore W2066257706C54173615 @default.
• W2066257706 hasConceptScore W2066257706C71924100 @default.
• W2066257706 hasConceptScore W2066257706C98274493 @default.
• W2066257706 hasLocation W20662577061 @default.
• W2066257706 hasLocation W20662577062 @default.
• W2066257706 hasLocation W20662577063 @default.
• W2066257706 hasLocation W20662577064 @default.
• W2066257706 hasOpenAccess W2066257706 @default.
• W2066257706 hasPrimaryLocation W20662577061 @default.
• W2066257706 hasRelatedWork W1606470965 @default.
• W2066257706 hasRelatedWork W1685198220 @default.
• W2066257706 hasRelatedWork W1970608583 @default.
• W2066257706 hasRelatedWork W1989563210 @default.
• W2066257706 hasRelatedWork W2020220553 @default.
• W2066257706 hasRelatedWork W2027983015 @default.
• W2066257706 hasRelatedWork W2028865611 @default.
• W2066257706 hasRelatedWork W2097680988 @default.
• W2066257706 hasRelatedWork W2105096946 @default.
• W2066257706 hasRelatedWork W2114961719 @default.
• W2066257706 hasRelatedWork W2123993504 @default.
• W2066257706 hasRelatedWork W2358561188 @default.
• W2066257706 hasRelatedWork W2382285893 @default.
• W2066257706 hasRelatedWork W2391011999 @default.
• W2066257706 hasRelatedWork W2397957036 @default.
• W2066257706 hasRelatedWork W2947808196 @default.
• W2066257706 hasRelatedWork W3141522254 @default.
• W2066257706 hasRelatedWork W69327081 @default.
• W2066257706 hasRelatedWork W2186999306 @default.
• W2066257706 hasRelatedWork W3139723578 @default.
• W2066257706 isParatext "false" @default.
• W2066257706 isRetracted "false" @default.

• next