Matches in SemOpenAlex for { <https://semopenalex.org/work/W2066270160> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2066270160 endingPage "2240" @default.
- W2066270160 startingPage "2235" @default.
- W2066270160 abstract "Amsacrine (AMSA) and cyclocytidine were studied as retrieval therapy in 122 pediatric patients with acute nonlymphoblastic leukemia (ANLL). Patients either failed to achieve sustained initial remissions or were in relapse. Induction therapy consisted of intravenous (IV) AMSA (75 mg/m2) from days 1 to 5 and subcutaneous cyclocytidine (600 mg/m2) from days 1 to 7. Maintenance therapy consisted of IV etoposide (VP-16) (100 mg/m2) for 5 days and IV AMSA (100 mg/m2) on day 1. Of 122 patients, 109 were evaluable. There were 13 early deaths. Ninety-six patients received adequate therapy defined as completion of two courses of therapy. Of these 96 patients, 52 achieved complete remission. Fifteen of 33 patients who failed initial induction achieved complete remission. Eighteen of 39 patients who were resistant to anthracyclines had complete responses. There was no direct evidence of AMSA-induced cardiotoxicity. Remission duration was 28 days to 3 or more years (median, 98 days). AMSA and cyclocytidine were effective retrieval therapy for patients who were in relapse or unresponsive to frontline therapy. Duration of remission was short (median, 98 days)." @default.
- W2066270160 created "2016-06-24" @default.
- W2066270160 creator A5006221398 @default.
- W2066270160 creator A5010503749 @default.
- W2066270160 creator A5012145891 @default.
- W2066270160 creator A5015594143 @default.
- W2066270160 creator A5020855674 @default.
- W2066270160 creator A5026088642 @default.
- W2066270160 creator A5028334828 @default.
- W2066270160 creator A5069315847 @default.
- W2066270160 date "1991-05-01" @default.
- W2066270160 modified "2023-10-16" @default.
- W2066270160 title "Successful reinduction therapy with amsacrine and cyclocytidine in acute nonlymphoblastic leukemia in children. A report from the childrens cancer study group" @default.
- W2066270160 cites W175276807 @default.
- W2066270160 cites W1934064433 @default.
- W2066270160 cites W1993402909 @default.
- W2066270160 cites W2040785900 @default.
- W2066270160 cites W2042973065 @default.
- W2066270160 cites W2077099625 @default.
- W2066270160 cites W2094311764 @default.
- W2066270160 cites W2167805334 @default.
- W2066270160 cites W2263355311 @default.
- W2066270160 cites W2338217525 @default.
- W2066270160 cites W2403113009 @default.
- W2066270160 cites W2406249232 @default.
- W2066270160 doi "https://doi.org/10.1002/1097-0142(19910501)67:9<2235::aid-cncr2820670904>3.0.co;2-2" @default.
- W2066270160 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1707336" @default.
- W2066270160 hasPublicationYear "1991" @default.
- W2066270160 type Work @default.
- W2066270160 sameAs 2066270160 @default.
- W2066270160 citedByCount "19" @default.
- W2066270160 countsByYear W20662701602016 @default.
- W2066270160 crossrefType "journal-article" @default.
- W2066270160 hasAuthorship W2066270160A5006221398 @default.
- W2066270160 hasAuthorship W2066270160A5010503749 @default.
- W2066270160 hasAuthorship W2066270160A5012145891 @default.
- W2066270160 hasAuthorship W2066270160A5015594143 @default.
- W2066270160 hasAuthorship W2066270160A5020855674 @default.
- W2066270160 hasAuthorship W2066270160A5026088642 @default.
- W2066270160 hasAuthorship W2066270160A5028334828 @default.
- W2066270160 hasAuthorship W2066270160A5069315847 @default.
- W2066270160 hasBestOaLocation W20662701601 @default.
- W2066270160 hasConcept C121608353 @default.
- W2066270160 hasConcept C126322002 @default.
- W2066270160 hasConcept C141071460 @default.
- W2066270160 hasConcept C2776694085 @default.
- W2066270160 hasConcept C2778119113 @default.
- W2066270160 hasConcept C2780500152 @default.
- W2066270160 hasConcept C3018657049 @default.
- W2066270160 hasConcept C71924100 @default.
- W2066270160 hasConcept C90924648 @default.
- W2066270160 hasConceptScore W2066270160C121608353 @default.
- W2066270160 hasConceptScore W2066270160C126322002 @default.
- W2066270160 hasConceptScore W2066270160C141071460 @default.
- W2066270160 hasConceptScore W2066270160C2776694085 @default.
- W2066270160 hasConceptScore W2066270160C2778119113 @default.
- W2066270160 hasConceptScore W2066270160C2780500152 @default.
- W2066270160 hasConceptScore W2066270160C3018657049 @default.
- W2066270160 hasConceptScore W2066270160C71924100 @default.
- W2066270160 hasConceptScore W2066270160C90924648 @default.
- W2066270160 hasIssue "9" @default.
- W2066270160 hasLocation W20662701601 @default.
- W2066270160 hasLocation W20662701602 @default.
- W2066270160 hasOpenAccess W2066270160 @default.
- W2066270160 hasPrimaryLocation W20662701601 @default.
- W2066270160 hasRelatedWork W2064930805 @default.
- W2066270160 hasRelatedWork W2066270160 @default.
- W2066270160 hasRelatedWork W2068844189 @default.
- W2066270160 hasRelatedWork W2072897419 @default.
- W2066270160 hasRelatedWork W2094373011 @default.
- W2066270160 hasRelatedWork W2403834487 @default.
- W2066270160 hasRelatedWork W2409422591 @default.
- W2066270160 hasRelatedWork W2416306481 @default.
- W2066270160 hasRelatedWork W2416808696 @default.
- W2066270160 hasRelatedWork W2188248547 @default.
- W2066270160 hasVolume "67" @default.
- W2066270160 isParatext "false" @default.
- W2066270160 isRetracted "false" @default.
- W2066270160 magId "2066270160" @default.
- W2066270160 workType "article" @default.