Matches in SemOpenAlex for { <https://semopenalex.org/work/W2066280715> ?p ?o ?g. }
- W2066280715 endingPage "609" @default.
- W2066280715 startingPage "601" @default.
- W2066280715 abstract "We report the serendipitous discovery of a human plasma phosphate binding protein (HPBP). This 38 kDa protein is copurified with the enzyme paraoxonase. Its X-ray structure is similar to the prokaryotic phosphate solute binding proteins (SBPs) associated with ATP binding cassette transmembrane transporters, though phosphate-SBPs have never been characterized or predicted from nucleic acid databases in eukaryotes. However, HPBP belongs to the family of ubiquitous eukaryotic proteins named DING, meaning that phosphate-SBPs are also widespread in eukaryotes. The systematic absence of complete genes for eukaryotic phosphate-SBP from databases is intriguing, but the astonishing 90% sequence conservation between genes belonging to evolutionary distant species suggests that the corresponding proteins play an important function. HPBP is the only known transporter capable of binding phosphate ions in human plasma and may become a new predictor of or a potential therapeutic agent for phosphate-related diseases such as atherosclerosis." @default.
- W2066280715 created "2016-06-24" @default.
- W2066280715 creator A5003144687 @default.
- W2066280715 creator A5012751862 @default.
- W2066280715 creator A5015709474 @default.
- W2066280715 creator A5015990767 @default.
- W2066280715 creator A5029338783 @default.
- W2066280715 creator A5036781360 @default.
- W2066280715 creator A5037524436 @default.
- W2066280715 creator A5046983684 @default.
- W2066280715 creator A5047979165 @default.
- W2066280715 creator A5050037997 @default.
- W2066280715 creator A5061880388 @default.
- W2066280715 creator A5085208614 @default.
- W2066280715 creator A5087373372 @default.
- W2066280715 creator A5089589427 @default.
- W2066280715 creator A5089636420 @default.
- W2066280715 creator A5091354648 @default.
- W2066280715 date "2006-03-01" @default.
- W2066280715 modified "2023-10-17" @default.
- W2066280715 title "Serendipitous Discovery and X-Ray Structure of a Human Phosphate Binding Apolipoprotein" @default.
- W2066280715 cites W1482516139 @default.
- W2066280715 cites W1587136965 @default.
- W2066280715 cites W1591680814 @default.
- W2066280715 cites W1648289207 @default.
- W2066280715 cites W1671050155 @default.
- W2066280715 cites W1860908381 @default.
- W2066280715 cites W1902666753 @default.
- W2066280715 cites W1987202977 @default.
- W2066280715 cites W1987933268 @default.
- W2066280715 cites W1995017064 @default.
- W2066280715 cites W1999521309 @default.
- W2066280715 cites W2000840258 @default.
- W2066280715 cites W2001641653 @default.
- W2066280715 cites W2006304581 @default.
- W2066280715 cites W2007315168 @default.
- W2066280715 cites W2019455412 @default.
- W2066280715 cites W2019642817 @default.
- W2066280715 cites W2023926358 @default.
- W2066280715 cites W2032831735 @default.
- W2066280715 cites W2033465115 @default.
- W2066280715 cites W2039752223 @default.
- W2066280715 cites W2046482376 @default.
- W2066280715 cites W2054448964 @default.
- W2066280715 cites W2058550654 @default.
- W2066280715 cites W2066139224 @default.
- W2066280715 cites W2067605416 @default.
- W2066280715 cites W2069097757 @default.
- W2066280715 cites W2083221094 @default.
- W2066280715 cites W2084627135 @default.
- W2066280715 cites W2090529688 @default.
- W2066280715 cites W2094303590 @default.
- W2066280715 cites W2096943217 @default.
- W2066280715 cites W2101446086 @default.
- W2066280715 cites W2112315506 @default.
- W2066280715 cites W2113147520 @default.
- W2066280715 cites W2113743966 @default.
- W2066280715 cites W2114197469 @default.
- W2066280715 cites W2115840790 @default.
- W2066280715 cites W2116128404 @default.
- W2066280715 cites W2118455767 @default.
- W2066280715 cites W2119674873 @default.
- W2066280715 cites W2123094796 @default.
- W2066280715 cites W2129078368 @default.
- W2066280715 cites W2150545098 @default.
- W2066280715 cites W2162097287 @default.
- W2066280715 cites W2164259487 @default.
- W2066280715 cites W2339616051 @default.
- W2066280715 cites W77392274 @default.
- W2066280715 doi "https://doi.org/10.1016/j.str.2005.12.012" @default.
- W2066280715 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16531243" @default.
- W2066280715 hasPublicationYear "2006" @default.
- W2066280715 type Work @default.
- W2066280715 sameAs 2066280715 @default.
- W2066280715 citedByCount "82" @default.
- W2066280715 countsByYear W20662807152012 @default.
- W2066280715 countsByYear W20662807152013 @default.
- W2066280715 countsByYear W20662807152014 @default.
- W2066280715 countsByYear W20662807152015 @default.
- W2066280715 countsByYear W20662807152016 @default.
- W2066280715 countsByYear W20662807152017 @default.
- W2066280715 countsByYear W20662807152018 @default.
- W2066280715 countsByYear W20662807152020 @default.
- W2066280715 countsByYear W20662807152021 @default.
- W2066280715 countsByYear W20662807152022 @default.
- W2066280715 crossrefType "journal-article" @default.
- W2066280715 hasAuthorship W2066280715A5003144687 @default.
- W2066280715 hasAuthorship W2066280715A5012751862 @default.
- W2066280715 hasAuthorship W2066280715A5015709474 @default.
- W2066280715 hasAuthorship W2066280715A5015990767 @default.
- W2066280715 hasAuthorship W2066280715A5029338783 @default.
- W2066280715 hasAuthorship W2066280715A5036781360 @default.
- W2066280715 hasAuthorship W2066280715A5037524436 @default.
- W2066280715 hasAuthorship W2066280715A5046983684 @default.
- W2066280715 hasAuthorship W2066280715A5047979165 @default.
- W2066280715 hasAuthorship W2066280715A5050037997 @default.
- W2066280715 hasAuthorship W2066280715A5061880388 @default.
- W2066280715 hasAuthorship W2066280715A5085208614 @default.