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- W2066295910 abstract "Sensitivity to proteolytic degradation was used to monitor folding of polypeptides in vivo. A correlation between competence for export and lack of stable tertiary structure was established by comparing the kinetics of folding of mutated precursor maltose-binding protein that carries a defective leader peptide with the kinetics of folding of wild-type precursor that is competent for export. It is proposed that during export a kinetic competition exists between productive translocation and folding of precursor intracellularly into a stable conformation that is not compatible with transfer." @default.
- W2066295910 created "2016-06-24" @default.
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- W2066295910 date "1986-09-01" @default.
- W2066295910 modified "2023-09-30" @default.
- W2066295910 title "Correlation of competence for export with lack of tertiary structure of the mature species: A study in vivo of maltose-binding protein in E. coli" @default.
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- W2066295910 doi "https://doi.org/10.1016/0092-8674(86)90074-7" @default.
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