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• W2066356670 abstract "Several investigators have observed, under conditions of little or no gas exchange, that large differences in PCO2 can occur between mixed venous blood and alveolar gas ( Jones et al., 1969 Jones NL Campbell EJM Edwards RHT et al. Alveolar to blood PCO2 differences during rebreathing in exercise. J Appl Physiol. 1969; 27: 356-360 Crossref PubMed Scopus (5) Google Scholar ; Gurtner et al., 1969 Gurtner GH Song SH Farhi LE Alveolar to mixed venous PCO2 differences under conditions of no gas exchange. Resp Physiol. 1969; 71: 173-187 Crossref Scopus (25) Google Scholar ; Dennison et al., 1969 Dennison D Edwards RH Jones G et al. Direct and rebreathing estimates of the O2 and CO2 pressures in mixed venous blood. Resp Physiol. 1969; 7: 326-334 Crossref PubMed Scopus (19) Google Scholar , Guyatt, 2015 Guyatt AR, Yu CJ, Lutherer B, et al: Studies of alveolar-mixed venous CO2 and O2 gradients in the rebreathing dog lung. Resp Physiol (in press) Google Scholar ). Gurtner et al., 1969 Gurtner GH Song SH Farhi LE Alveolar to mixed venous PCO2 differences under conditions of no gas exchange. Resp Physiol. 1969; 71: 173-187 Crossref Scopus (25) Google Scholar have found that ΔPCO2 was related to both [H+] and [HCO3-] activity by the mixed venous blood. They developed a model explaining their results which involves a coupling of bulk flow, diffusion and chemical reaction near a negatively charged capillary wall. This model was considered in their article which appeared in Resp Physiol and will be considered only briefly at the present time. The model postulates an intracapillary H+ difference due to a negatively charged capillary wall. There is a large amount of evidence that walls of blood vessels carry fixed negative charges. This evidence is reviewed in the 1969 paper." @default.
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• W2066356670 title "Steady State Differences in PCO2 [HCO3-] and [H+] between Blood and Extravascular Tissue Results for Lung, CSF and Brain" @default.
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